Genomic Location: NC_064037.1:15778039...15808328
NR annotation: XP_032241813.2, ARF GTPase-activating protein GIT2 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5516103 |
| Transcript |
| rna-XM_032385922.2 |
| Protein |
| XP_032241813.2 |
| UniProt accession | Description |
|---|---|
| Q14161 | ARF GTPase-activating protein GIT2 OS=Homo sapiens OX=9606 GN=GIT2 PE=1 SV=2 |
| Q68FF6 | ARF GTPase-activating protein GIT1 OS=Mus musculus OX=10090 GN=Git1 PE=1 SV=1 |
| Q9Z272 | ARF GTPase-activating protein GIT1 OS=Rattus norvegicus OX=10116 GN=Git1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004494 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01412 all species → | ArfGap | Putative GTPase activating protein for Arf | Domain | Interproscan |
| PF12796 all species → | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| PF08518 all species → | GIT_SHD | Spa2 homology domain (SHD) of GIT | Family | Interproscan |
| PF16559 all species → | GIT_CC | GIT coiled-coil Rho guanine nucleotide exchange factor | Coiled-coil | Interproscan |
| PF12205 all species → | GIT1_C | G protein-coupled receptor kinase-interacting protein 1 C term | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR038508 all species → | Homologous_superfamily | ArfGAP domain superfamily | Interproscan |
| IPR013724 all species → | Domain | GIT, Spa2 homology (SHD) domain | Interproscan |
| IPR036770 all species → | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR037278 all species → | Homologous_superfamily | ARFGAP/RecO-like zinc finger | Interproscan |
| IPR047161 all species → | Family | ARF GTPase-activating protein Git-like | Interproscan |
| IPR001164 all species → | Domain | Arf GTPase activating protein | Interproscan |
| IPR002110 all species → | Repeat | Ankyrin repeat | Interproscan |
| IPR032352 all species → | Domain | Arf GTPase-activating protein GIT1/2, coiled-coil domain | Interproscan |
| IPR022018 all species → | Domain | ARF GTPase-activating protein GIT1, C-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46097 all species → | G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAP | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005096 all species → | Molecular Function | GTPase activator activity | Interproscan |
| GO:0007420 all species → | Biological Process | brain development | Interproscan |
| GO:0008277 all species → | Biological Process | regulation of G protein-coupled receptor signaling pathway | Interproscan |
| GO:0031267 all species → | Molecular Function | small GTPase binding | Interproscan |
| GO:0032012 all species → | Biological Process | regulation of ARF protein signal transduction | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K12487 | GIT2; G protein-coupled receptor kinase interactor 2 | - | Membrane trafficking | ko04131 | deepkoala |
Transcript abundance of XP_032241813.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 28.34 | 28.75 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 19.30 | 26.67 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 16.53 | 18.71 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 19.32 | 24.28 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 15.67 | 17.04 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 2 | 19.02 | 33.61 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 27.72 | 29.33 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 31.93 | 35.10 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 22.28 | 34.71 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 33.10 | 34.36 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 28.03 | 31.12 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 28.24 | 30.61 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 29.72 | 31.37 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 21.33 | 35.67 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 23.30 | 27.93 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 2 | 14.01 | 27.95 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.