Detailed information of XP_032241813.2 in Nematostella vectensis

Genomic Location: NC_064037.1:15778039...15808328
NR annotation: XP_032241813.2, ARF GTPase-activating protein GIT2 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q14161ARF GTPase-activating protein GIT2 OS=Homo sapiens OX=9606 GN=GIT2 PE=1 SV=2
Q68FF6ARF GTPase-activating protein GIT1 OS=Mus musculus OX=10090 GN=Git1 PE=1 SV=1
Q9Z272ARF GTPase-activating protein GIT1 OS=Rattus norvegicus OX=10116 GN=Git1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0004494 (this species only)

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01412
all species →
ArfGapPutative GTPase activating protein for ArfDomainInterproscan
PF12796
all species →
Ank_2Ankyrin repeats (3 copies)RepeatInterproscan
PF08518
all species →
GIT_SHDSpa2 homology domain (SHD) of GITFamilyInterproscan
PF16559
all species →
GIT_CCGIT coiled-coil Rho guanine nucleotide exchange factorCoiled-coilInterproscan
PF12205
all species →
GIT1_CG protein-coupled receptor kinase-interacting protein 1 C termDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR038508
all species →
Homologous_superfamilyArfGAP domain superfamilyInterproscan
IPR013724
all species →
DomainGIT, Spa2 homology (SHD) domainInterproscan
IPR036770
all species →
Homologous_superfamilyAnkyrin repeat-containing domain superfamilyInterproscan
IPR037278
all species →
Homologous_superfamilyARFGAP/RecO-like zinc fingerInterproscan
IPR047161
all species →
FamilyARF GTPase-activating protein Git-likeInterproscan
IPR001164
all species →
DomainArf GTPase activating proteinInterproscan
IPR002110
all species →
RepeatAnkyrin repeatInterproscan
IPR032352
all species →
DomainArf GTPase-activating protein GIT1/2, coiled-coil domainInterproscan
IPR022018
all species →
DomainARF GTPase-activating protein GIT1, C-terminalInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46097
all species →
G PROTEIN-COUPLED RECEPTOR KINASE INTERACTING ARFGAPInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005096
all species →
Molecular FunctionGTPase activator activityInterproscan
GO:0007420
all species →
Biological Processbrain developmentInterproscan
GO:0008277
all species →
Biological Processregulation of G protein-coupled receptor signaling pathwayInterproscan
GO:0031267
all species →
Molecular Functionsmall GTPase bindingInterproscan
GO:0032012
all species →
Biological Processregulation of ARF protein signal transductionInterproscan
GO:0005515
all species →
Molecular Functionprotein bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K12487GIT2; G protein-coupled receptor kinase interactor 2-Membrane traffickingko04131deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032241813.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
44TPM > 0
16Conditions
35.7Max TPM
23.6Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole 6 week old aboral regenerate · regenerate 96hpa 3 3 28.34 28.75
whole 6 week old aboral regenerate · regenerate 144hpa 3 3 19.30 26.67
whole 6 week old aboral regenerate · regenerate 0hpa 3 3 16.53 18.71
whole 6 week old aboral regenerate · regenerate 2hpa 3 3 19.32 24.28
whole 6 week old aboral regenerate · regenerate uncut 3 3 15.67 17.04
whole 6 week old aboral regenerate · regenerate 4hpa 3 2 19.02 33.61
whole 6 week old aboral regenerate · regenerate 120hpa 3 3 27.72 29.33
whole 6 week old aboral regenerate · regenerate 36hpa 3 3 31.93 35.10
whole 6 week old aboral regenerate · regenerate 24hpa 3 2 22.28 34.71
whole 6 week old aboral regenerate · regenerate 20hpa 3 3 33.10 34.36
whole 6 week old aboral regenerate · regenerate 16hpa 3 3 28.03 31.12
whole 6 week old aboral regenerate · regenerate 72hpa 3 3 28.24 30.61
whole 6 week old aboral regenerate · regenerate 60hpa 3 3 29.72 31.37
whole 6 week old aboral regenerate · regenerate 48hpa 3 2 21.33 35.67
whole 6 week old aboral regenerate · regenerate 8hpa 3 3 23.30 27.93
whole 6 week old aboral regenerate · regenerate 12hpa 3 2 14.01 27.95

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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