Genomic Location: NC_064037.1:11132790...11155445
NR annotation: XP_032242257.2, small G protein signaling modulator 2 isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5516531 |
| Transcript |
| rna-XM_032386366.2 |
| Protein |
| XP_032242257.2 |
| UniProt accession | Description |
|---|---|
| O43147 | Small G protein signaling modulator 2 OS=Homo sapiens OX=9606 GN=SGSM2 PE=1 SV=4 |
| Q8BPQ7 | Small G protein signaling modulator 1 OS=Mus musculus OX=10090 GN=Sgsm1 PE=1 SV=2 |
| Q80U12 | Small G protein signaling modulator 2 OS=Mus musculus OX=10090 GN=Sgsm2 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003723 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02759 all species → | RUN | RUN domain | Family | Interproscan |
| PF00566 all species → | RabGAP-TBC | Rab-GTPase-TBC domain | Family | Interproscan |
| PF12068 all species → | PH_RBD | Rab-binding domain (RBD) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004012 all species → | Domain | RUN domain | Interproscan |
| IPR000195 all species → | Domain | Rab-GAP-TBC domain | Interproscan |
| IPR035969 all species → | Homologous_superfamily | Rab-GAP-TBC domain superfamily | Interproscan |
| IPR037213 all species → | Homologous_superfamily | RUN domain superfamily | Interproscan |
| IPR037745 all species → | Domain | Small G protein signalling modulator 1/2, PH domain | Interproscan |
| IPR021935 all species → | Domain | Small G protein signalling modulator 1/2, Rab-binding domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR22957 all species → | TBC1 DOMAIN FAMILY MEMBER GTPASE-ACTIVATING PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005096 all species → | Molecular Function | GTPase activator activity | Interproscan |
| GO:0090630 all species → | Biological Process | activation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K21847 | SGSM1, RUTBC2; small G protein signaling modulator 1 | - | Membrane trafficking | ko04131 | deepkoala |
Transcript abundance of XP_032242257.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 34.77 | 41.69 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 27.49 | 34.52 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 25.13 | 28.60 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 27.71 | 32.77 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 26.10 | 29.60 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 3 | 30.75 | 34.16 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 34.47 | 39.89 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 36.02 | 39.10 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 3 | 35.06 | 41.91 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 38.95 | 40.51 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 36.10 | 42.19 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 33.02 | 36.53 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 31.88 | 35.69 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 3 | 39.67 | 48.18 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 34.34 | 41.28 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 3 | 37.16 | 41.61 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.