Gene detail

Detailed information of XP_032242684.2 in Nematostella vectensis

Genomic Location: NC_064045.1:3877182...3887653
NR annotation: XP_032242684.2, GATOR complex protein NPRL3 isoform X2 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_032386793.2

GTTGTCTTATTTGTATACTTGTAGGAATGCTGTGGTTTTATGACTAGGCCCATTCTCCCCTgatttcaagatggcggggATGGTAACTCAAGTACGTGAAGAAAATGTGTAGTGTTTTGATTACAAGAGGATGGATTATTCATCCCGCTGCAGTCCCGTGAGTGTCATTTTGGTAACCGCCGGTAGCCGAGGCCAGAGAGTGCTGTTTCGATATCCTTATCAGTCCAACTCCGACGAAGGCGAAAGAGAGTCCAGCAAAAGTCATTATGCATTACCTCACAGTAATGAGGGATGCAGTGCAAGGTTCTCGGACAGCACTCTTGCAAATATCCTCACACCTAAACCCATGCTATGTGGACAGAGGTTTGAGCTCAAAATTGACAACATGTTATTTGTTGGCCATCCTATGCTGTTGAATGAATCAAATAGGGGAGATGGAAGAAAAGAGGAAGTCATGATGAAGCTGTTTAACATCGTCTTTATATTGAAGGCTGAGGCTGATCCAACATTAATAAGTAGCTACCATGATCTGTCTAAGAGACTTGCAATTGCCTTGAAACATGAGGAAAGAAGGTGTCGTTATTTGACCAAGGAAAGAGAAACAATGCTTGCTGTCCATGATGAGGTCTGTTCTATGCCTGAGGACTGCGCAGAATCACCATTTCTTCATATGCTACCCAAAAGTAAACTTGCTGTTGATTTGAAGGACTCATTTGAAAGTTTGTGTACCACTGGTGTTGTCCAAATTAGGATCAACGGATGGGTGAATGTCAGTTTTTGCCTCCCGCAGAAGGTCCATAATCTTCATCAGGGAATGCTAACCATTACGCCAAAAGCCATCGAAACATCCCTTGCCTCCATGAGGCCGTACCACACTCTTCTGTTTCTTGTGGATGAGGTATCACTTCTTGGGTTACTCCCGGGTGACTGTTCCCCTGCTGTGACTAGGCTTATTCGCATGGCAACCCCTCTCAAGAGCTTCACAGCTCTATCACAAGACACAGACATTCCATTGTCCCAGCTGTTTGCGATAGCGGCGCATCTTGTGCACTGGGGAAAAGCTTCAATCATCTATCCTCTCTGTGAGAGCAATCTTTATGTCGTGGCACAAAGCCTTAATATGAACACGCTCTCTCCTCTGGCGGAGGGATATGCTGCAAGTTTTCCGGGAAAGTCCCTGCATGCAACGCTGGCCGATTTTTCGTTACCAAGCCCCCTGGCGGAGCACTATAATCCCCTGGCCTCCCCCCAACAGCAGGCAGAGCAAGTTCAGATGGTGGTGTGGATGTTACAACACAGGCTGCTGATACAGCTCCATACCTACATATTCCTGGTACCGTCGGCTCAGCTTGAGCAGCAGTCAGACACCCAAGGGCGCATGCGCGACTGTCGTCGCATTCGCTGGATATTCGGCGGAAGCTTCACCGACGAGCTTCCTGTGTACCAAGACGAGGAGCCTCTAGGGGGGCCTGGTACCAGCTCAAGTCCAGAGTTTGGAGTTTTGAACAGTGTACCTAGTCTGACTTACTCTGAGATGCGGAGCATTCACCGCGTTCCTGCCGCCAAAAACGAGGAAGATCTAAAATTATTTGCCCGACTCGCGCCGTACTTCCGGGGTCGCCACCACTTGGAGGAAATCATGTACTATGAGAACTTGAGGCGATCACAATTGCTCACACTCATGGACAAGTTCCGAGATGTGCTGTATCTATGCCAGCACGAGGACCCTTCCACGGCATGCTTCCATAACCGATGATCGCCATGGTAGTGATGacaatggtggtgatgatgatggtggtgatgatgatggtgatgatgatgataatggtgatattgatggtgatgatgataacggtgatggtgattatgatctCAGCTACTGAAACTCATGGACAATTTCCGAGATGTGCTATATCTGTTCCAGCACGAGGATCCTACCACGgcatgctgatgatgatgatgcaatggtgatgatgataataataattgtttATTAATTATGACGACAACGAAATGCTTAAAAAATGCTAGTGTCTACATTTTTACTTTAATCCGAcctgaaataaatataaactgtTAACCGAGCATCTGAGCTTAAtaagttatttattatatggctttttttaatatctacACGAGAAGGACAACTTAAGCTGCTGAAGTGAATGAAGAAACCCTTTCTGGATTTACAAACCACGAGTGCTCACCTCCAAATCTCGAAATAATGAGTcgatttgtaaaatgaccatcgaagaaaaaataaatatgtaagcttatgtaataaaacaaccttttgttgttga

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8VIJ8	GATOR1 complex protein NPRL3 OS=Mus musculus OX=10090 GN=Nprl3 PE=1 SV=1
Q12980	GATOR1 complex protein NPRL3 OS=Homo sapiens OX=9606 GN=NPRL3 PE=1 SV=1
Q9VUB4	GATOR complex protein NPRL3 OS=Drosophila melanogaster OX=7227 GN=Nprl3 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004337 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF03666 all species →	NPR3	Nitrogen Permease regulator of amino acid transport activity 3	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR005365 all species →	Family	Nitrogen permease regulator 3	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13153 all species →	CGTHBA PROTEIN -14 GENE PROTEIN	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0010508 all species →	Biological Process	positive regulation of autophagy	Interproscan
GO:0032007 all species →	Biological Process	negative regulation of TOR signaling	Interproscan
GO:0034198 all species →	Biological Process	cellular response to amino acid starvation	Interproscan
GO:0038202 all species →	Biological Process	TORC1 signaling	Interproscan
GO:1904262 all species →	Biological Process	negative regulation of TORC1 signaling	Interproscan
GO:1990130 all species →	Cellular Component	GATOR1 complex	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K20406	NPRL3, NPR3; nitrogen permease regulator 3	-	Membrane trafficking	ko04131	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032242684.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

40TPM > 0

16Conditions

32.0Max TPM

10.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole 6 week old aboral regenerate · regenerate 96hpa	3	3	11.33	13.94
whole 6 week old aboral regenerate · regenerate 144hpa	3	3	10.92	12.77
whole 6 week old aboral regenerate · regenerate 0hpa	3	3	10.94	11.09
whole 6 week old aboral regenerate · regenerate 2hpa	3	3	8.59	9.82
whole 6 week old aboral regenerate · regenerate uncut	3	3	10.40	10.76
whole 6 week old aboral regenerate · regenerate 4hpa	3	2	6.30	9.66
whole 6 week old aboral regenerate · regenerate 120hpa	3	2	7.34	11.09
whole 6 week old aboral regenerate · regenerate 36hpa	3	3	12.28	14.64
whole 6 week old aboral regenerate · regenerate 24hpa	3	2	8.49	13.38
whole 6 week old aboral regenerate · regenerate 20hpa	3	3	12.20	12.77
whole 6 week old aboral regenerate · regenerate 16hpa	3	3	12.65	13.29
whole 6 week old aboral regenerate · regenerate 72hpa	3	2	8.30	13.84
whole 6 week old aboral regenerate · regenerate 60hpa	3	3	12.86	14.56
whole 6 week old aboral regenerate · regenerate 48hpa	3	2	15.20	32.01
whole 6 week old aboral regenerate · regenerate 8hpa	3	2	9.36	14.85
whole 6 week old aboral regenerate · regenerate 12hpa	3	1	3.87	11.62

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6320837	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	13.94
SRR6320836	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	12.64
SRR6320863	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	7.41
SRR6320847	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	12.77
SRR6320838	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	10.59
SRR6320841	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	9.38
SRR6320839	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	11.09
SRR6320846	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	10.97
SRR6320840	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	10.77
SRR6320861	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	9.82
SRR6320842	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	8.25
SRR6320848	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	7.70
SRR6320845	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	10.76
SRR6320844	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	10.37
SRR6320843	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	10.09
SRR6320872	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	9.66
SRR6320849	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	9.25
SRR6320873	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	0.00
SRR6320883	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	11.09
SRR6320882	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	10.94
SRR6320850	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	0.00
SRR6320851	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	14.64
SRR6320855	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	12.11
SRR6320852	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	10.08
SRR6320854	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	13.38
SRR6320853	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	12.10
SRR6320856	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	0.00
SRR6320860	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	12.77
SRR6320859	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	12.70
SRR6320857	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	11.12
SRR6320880	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	13.29
SRR6320858	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	12.73
SRR6320881	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	11.94
SRR6320862	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	13.84
SRR6320865	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	11.08
SRR6320864	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	0.00
SRR6320869	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	14.56
SRR6320866	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	13.12
SRR6320867	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	10.89
SRR6320868	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	32.01
SRR6320870	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	13.60
SRR6320871	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	0.00
SRR6320874	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	14.85
SRR6320875	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	13.23
SRR6320876	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	0.00
SRR6320877	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	11.62
SRR6320878	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00
SRR6320879	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.