Genomic Location: NC_064045.1:3206421...3214998
NR annotation: XP_032242729.2, crossover junction endonuclease EME1 isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5516851 |
| Transcript |
| rna-XM_032386838.2 |
| Protein |
| XP_032242729.2 |
| UniProt accession | Description |
|---|---|
| Q96AY2 | Structure-specific endonuclease subunit EME1 OS=Homo sapiens OX=9606 GN=EME1 PE=1 SV=2 |
| Q5NVA9 | Structure-specific endonuclease subunit EME1 OS=Pongo abelii OX=9601 GN=EME1 PE=3 SV=1 |
| Q8BJW7 | Structure-specific endonuclease subunit EME1 OS=Mus musculus OX=10090 GN=Eme1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004929 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21292 all species → | EME1-MUS81_C | EME1/MUS81, C-terminal | Domain | Interproscan |
| PF02732 all species → | ERCC4 | ERCC4 domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR033310 all species → | Family | Mms4/EME1/EME2 | Interproscan |
| IPR043087 all species → | Homologous_superfamily | EME1, nuclease domain, subdomain 2 | Interproscan |
| IPR043086 all species → | Homologous_superfamily | EME1, nuclease domain, subdomain 1 | Interproscan |
| IPR042530 all species → | Homologous_superfamily | EME1/EME2, C-terminal domain | Interproscan |
| IPR006166 all species → | Domain | ERCC4 domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR21077 all species → | EME1 PROTEIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000712 all species → | Biological Process | resolution of meiotic recombination intermediates | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0006281 all species → | Biological Process | DNA repair | Interproscan |
| GO:0006302 all species → | Biological Process | double-strand break repair | Interproscan |
| GO:0008821 all species → | Molecular Function | crossover junction DNA endonuclease activity | Interproscan |
| GO:0031297 all species → | Biological Process | replication fork processing | Interproscan |
| GO:0031573 all species → | Biological Process | mitotic intra-S DNA damage checkpoint signaling | Interproscan |
| GO:0048476 all species → | Cellular Component | Holliday junction resolvase complex | Interproscan |
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0004518 all species → | Molecular Function | nuclease activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K10882 | EME1, MMS4; crossover junction endonuclease EME1 | EC:3.1.22.- | DNA repair and recombination proteins | ko03400 | deepkoala |
Transcript abundance of XP_032242729.2 across 48 RNA-seq samples of Nematostella vectensis. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 0 | 0.00 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
