Detailed information of XP_032242778.2 in Nematostella vectensis

Genomic Location: NC_064045.1:3780016...3790622
NR annotation: XP_032242778.2, hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O14964Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens OX=9606 GN=HGS PE=1 SV=1
Q0V8S0Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Bos taurus OX=9913 GN=HGS PE=2 SV=1
Q9JJ50Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Rattus norvegicus OX=10116 GN=Hgs PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003104 (this species only)
Ubiquitin familyUBD|Alpha-Helix|VHS · all ubiquitin genes in this species

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF01363
all species →
FYVEFYVE zinc fingerDomainInterproscan
PF12210
all species →
Hrs_helicalHepatocyte growth factor-regulated tyrosine kinase substrateDomainInterproscan
PF00790
all species →
VHSVHS domainRepeatInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR017455
all species →
DomainZinc finger, FYVE-relatedInterproscan
IPR011011
all species →
Homologous_superfamilyZinc finger, FYVE/PHD-typeInterproscan
IPR017073
all species →
FamilyHepatocyte growth factor-regulated tyrosine kinase substrate/VPS27Interproscan
IPR008942
all species →
Homologous_superfamilyENTH/VHSInterproscan
IPR000306
all species →
DomainFYVE zinc fingerInterproscan
IPR002014
all species →
DomainVHS domainInterproscan
IPR024641
all species →
DomainHepatocyte growth factor-regulated tyrosine kinase substrate, helical domainInterproscan
IPR013083
all species →
Homologous_superfamilyZinc finger, RING/FYVE/PHD-typeInterproscan
IPR003903
all species →
Conserved_siteUbiquitin interacting motifInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46275
all species →
HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005769
all species →
Cellular Componentearly endosomeInterproscan
GO:0031623
all species →
Biological Processreceptor internalizationInterproscan
GO:0032456
all species →
Biological Processendocytic recyclingInterproscan
GO:0043130
all species →
Molecular Functionubiquitin bindingInterproscan
GO:0046872
all species →
Molecular Functionmetal ion bindingInterproscan
GO:0035091
all species →
Molecular Functionphosphatidylinositol bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K12182HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate-Membrane traffickingko04131deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032242778.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
43TPM > 0
16Conditions
29.6Max TPM
17.3Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole 6 week old aboral regenerate · regenerate 96hpa 3 3 17.40 19.09
whole 6 week old aboral regenerate · regenerate 144hpa 3 3 13.30 18.02
whole 6 week old aboral regenerate · regenerate 0hpa 3 3 15.40 17.95
whole 6 week old aboral regenerate · regenerate 2hpa 3 3 27.82 29.58
whole 6 week old aboral regenerate · regenerate uncut 3 3 15.77 17.09
whole 6 week old aboral regenerate · regenerate 4hpa 3 2 17.92 29.49
whole 6 week old aboral regenerate · regenerate 120hpa 3 3 17.37 18.93
whole 6 week old aboral regenerate · regenerate 36hpa 3 3 16.76 21.15
whole 6 week old aboral regenerate · regenerate 24hpa 3 2 15.43 25.67
whole 6 week old aboral regenerate · regenerate 20hpa 3 3 24.59 26.85
whole 6 week old aboral regenerate · regenerate 16hpa 3 3 21.19 23.49
whole 6 week old aboral regenerate · regenerate 72hpa 3 2 13.13 20.34
whole 6 week old aboral regenerate · regenerate 60hpa 3 3 16.51 19.03
whole 6 week old aboral regenerate · regenerate 48hpa 3 2 12.44 18.93
whole 6 week old aboral regenerate · regenerate 8hpa 3 3 15.88 17.37
whole 6 week old aboral regenerate · regenerate 12hpa 3 2 16.08 25.92

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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