Genomic Location: NC_064045.1:3780016...3790622
NR annotation: XP_032242778.2, hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5516931 |
| Transcript |
| rna-XM_032386887.2 |
| Protein |
| XP_032242778.2 |
| UniProt accession | Description |
|---|---|
| O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens OX=9606 GN=HGS PE=1 SV=1 |
| Q0V8S0 | Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Bos taurus OX=9913 GN=HGS PE=2 SV=1 |
| Q9JJ50 | Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Rattus norvegicus OX=10116 GN=Hgs PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003104 (this species only) |
| Ubiquitin family | UBD|Alpha-Helix|VHS · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01363 all species → | FYVE | FYVE zinc finger | Domain | Interproscan |
| PF12210 all species → | Hrs_helical | Hepatocyte growth factor-regulated tyrosine kinase substrate | Domain | Interproscan |
| PF00790 all species → | VHS | VHS domain | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR017455 all species → | Domain | Zinc finger, FYVE-related | Interproscan |
| IPR011011 all species → | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR017073 all species → | Family | Hepatocyte growth factor-regulated tyrosine kinase substrate/VPS27 | Interproscan |
| IPR008942 all species → | Homologous_superfamily | ENTH/VHS | Interproscan |
| IPR000306 all species → | Domain | FYVE zinc finger | Interproscan |
| IPR002014 all species → | Domain | VHS domain | Interproscan |
| IPR024641 all species → | Domain | Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR003903 all species → | Conserved_site | Ubiquitin interacting motif | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46275 all species → | HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005769 all species → | Cellular Component | early endosome | Interproscan |
| GO:0031623 all species → | Biological Process | receptor internalization | Interproscan |
| GO:0032456 all species → | Biological Process | endocytic recycling | Interproscan |
| GO:0043130 all species → | Molecular Function | ubiquitin binding | Interproscan |
| GO:0046872 all species → | Molecular Function | metal ion binding | Interproscan |
| GO:0035091 all species → | Molecular Function | phosphatidylinositol binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K12182 | HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate | - | Membrane trafficking | ko04131 | deepkoala |
Transcript abundance of XP_032242778.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 17.40 | 19.09 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 13.30 | 18.02 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 15.40 | 17.95 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 27.82 | 29.58 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 15.77 | 17.09 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 2 | 17.92 | 29.49 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 17.37 | 18.93 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 16.76 | 21.15 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 15.43 | 25.67 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 24.59 | 26.85 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 21.19 | 23.49 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 2 | 13.13 | 20.34 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 16.51 | 19.03 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 12.44 | 18.93 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 15.88 | 17.37 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 2 | 16.08 | 25.92 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.