Genomic Location: NC_064045.1:3780016...3790622
NR annotation: XP_032242778.2, hepatocyte growth factor-regulated tyrosine kinase substrate isoform X1 [Nematostella vectensis]
| CDS | |||||
| LOC5516931 | |||||
| Transcript |
| rna-XM_032386887.2 |
| Protein |
| XP_032242778.2 |
| Uniprot term | Description | ||||
|---|---|---|---|---|---|
| O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens OX=9606 GN=HGS PE=1 SV=1 | ||||
| Q0V8S0 | Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Bos taurus OX=9913 GN=HGS PE=2 SV=1 | ||||
| Q9JJ50 | Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Rattus norvegicus OX=10116 GN=Hgs PE=1 SV=1 |
| Gene family | Subfamily |
|---|---|
| Ubiquitin Family | UBD|Alpha-Helix|VHS |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01363 | FYVE | FYVE zinc finger | Domain | Interproscan |
| PF12210 | Hrs_helical | Hepatocyte growth factor-regulated tyrosine kinase substrate | Domain | Interproscan |
| PF00790 | VHS | VHS domain | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR017455 | Domain | Zinc finger, FYVE-related | Interproscan |
| IPR011011 | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR017073 | Family | Hepatocyte growth factor-regulated tyrosine kinase substrate/VPS27 | Interproscan |
| IPR008942 | Homologous_superfamily | ENTH/VHS | Interproscan |
| IPR000306 | Domain | FYVE zinc finger | Interproscan |
| IPR002014 | Domain | VHS domain | Interproscan |
| IPR024641 | Domain | Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain | Interproscan |
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR003903 | Conserved_site | Ubiquitin interacting motif | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46275 | HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005769 | Cellular Component | early endosome | Interproscan |
| GO:0031623 | Biological Process | receptor internalization | Interproscan |
| GO:0032456 | Biological Process | endocytic recycling | Interproscan |
| GO:0043130 | Molecular Function | ubiquitin binding | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0035091 | Molecular Function | phosphatidylinositol binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K12182 | HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate | - | Membrane trafficking | ko04131 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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