Genomic Location: NC_064045.1:3780017...3790622
NR annotation: XP_032242780.2, hepatocyte growth factor-regulated tyrosine kinase substrate isoform X3 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5516931 |
| Transcript |
| rna-XM_032386889.2 |
| Protein |
| XP_032242780.2 |
| UniProt accession | Description |
|---|---|
| Q99LI8 | Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Mus musculus OX=10090 GN=Hgs PE=1 SV=2 |
| O14964 | Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Homo sapiens OX=9606 GN=HGS PE=1 SV=1 |
| Q9JJ50 | Hepatocyte growth factor-regulated tyrosine kinase substrate OS=Rattus norvegicus OX=10116 GN=Hgs PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003104 (this species only) |
| Ubiquitin family | UBD|Alpha-Helix|VHS · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01363 all species → | FYVE | FYVE zinc finger | Domain | Interproscan |
| PF00790 all species → | VHS | VHS domain | Repeat | Interproscan |
| PF12210 all species → | Hrs_helical | Hepatocyte growth factor-regulated tyrosine kinase substrate | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR017455 all species → | Domain | Zinc finger, FYVE-related | Interproscan |
| IPR017073 all species → | Family | Hepatocyte growth factor-regulated tyrosine kinase substrate/VPS27 | Interproscan |
| IPR008942 all species → | Homologous_superfamily | ENTH/VHS | Interproscan |
| IPR000306 all species → | Domain | FYVE zinc finger | Interproscan |
| IPR002014 all species → | Domain | VHS domain | Interproscan |
| IPR011011 all species → | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR013083 all species → | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR024641 all species → | Domain | Hepatocyte growth factor-regulated tyrosine kinase substrate, helical domain | Interproscan |
| IPR003903 all species → | Conserved_site | Ubiquitin interacting motif | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46275 all species → | HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005769 all species → | Cellular Component | early endosome | Interproscan |
| GO:0031623 all species → | Biological Process | receptor internalization | Interproscan |
| GO:0032456 all species → | Biological Process | endocytic recycling | Interproscan |
| GO:0043130 all species → | Molecular Function | ubiquitin binding | Interproscan |
| GO:0046872 all species → | Molecular Function | metal ion binding | Interproscan |
| GO:0035091 all species → | Molecular Function | phosphatidylinositol binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K12182 | HGS, HRS, VPS27; hepatocyte growth factor-regulated tyrosine kinase substrate | - | Membrane trafficking | ko04131 | deepkoala |
Transcript abundance of XP_032242780.2 across 48 RNA-seq samples of Nematostella vectensis. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 0 | 0.00 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
