Genomic Location: NC_064036.1:1267252...1302612
NR annotation: XP_032242989.2, xanthine dehydrogenase/oxidase-like [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5517059 |
| Transcript |
| rna-XM_032387098.2 |
| Protein |
| XP_032242989.2 |
| UniProt accession | Description |
|---|---|
| P47989 | Xanthine dehydrogenase/oxidase OS=Homo sapiens OX=9606 GN=XDH PE=1 SV=4 |
| P47990 | Xanthine dehydrogenase/oxidase OS=Gallus gallus OX=9031 GN=XDH PE=1 SV=1 |
| P22985 | Xanthine dehydrogenase/oxidase OS=Rattus norvegicus OX=10116 GN=Xdh PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001251 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF20256 all species → | MoCoBD_2 | Molybdopterin cofactor-binding domain | Domain | Interproscan |
| PF00111 all species → | Fer2 | 2Fe-2S iron-sulfur cluster binding domain | Domain | Interproscan |
| PF01315 all species → | Ald_Xan_dh_C | Aldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domain | Domain | Interproscan |
| PF00941 all species → | FAD_binding_5 | FAD binding domain in molybdopterin dehydrogenase | Family | Interproscan |
| PF02738 all species → | MoCoBD_1 | Molybdopterin cofactor-binding domain | Domain | Interproscan |
| PF03450 all species → | CO_deh_flav_C | CO dehydrogenase flavoprotein C-terminal domain | Domain | Interproscan |
| PF01799 all species → | Fer2_2 | [2Fe-2S] binding domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR046867 all species → | Domain | Aldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domain | Interproscan |
| IPR036683 all species → | Homologous_superfamily | CO dehydrogenase flavoprotein, C-terminal domain superfamily | Interproscan |
| IPR016167 all species → | Homologous_superfamily | FAD-binding, type PCMH, subdomain 1 | Interproscan |
| IPR001041 all species → | Domain | 2Fe-2S ferredoxin-type iron-sulfur binding domain | Interproscan |
| IPR036856 all species → | Homologous_superfamily | Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamily | Interproscan |
| IPR000674 all species → | Domain | Aldehyde oxidase/xanthine dehydrogenase, a/b hammerhead | Interproscan |
| IPR002346 all species → | Domain | Molybdopterin dehydrogenase, FAD-binding | Interproscan |
| IPR008274 all species → | Domain | Aldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domain | Interproscan |
| IPR037165 all species → | Homologous_superfamily | Aldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamily | Interproscan |
| IPR016169 all species → | Homologous_superfamily | FAD-binding, type PCMH, subdomain 2 | Interproscan |
| IPR016166 all species → | Domain | FAD-binding domain, PCMH-type | Interproscan |
| IPR005107 all species → | Domain | CO dehydrogenase flavoprotein, C-terminal | Interproscan |
| IPR016208 all species → | Family | Aldehyde oxidase/xanthine dehydrogenase-like | Interproscan |
| IPR002888 all species → | Domain | [2Fe-2S]-binding | Interproscan |
| IPR036010 all species → | Homologous_superfamily | 2Fe-2S ferredoxin-like superfamily | Interproscan |
| IPR036318 all species → | Homologous_superfamily | FAD-binding, type PCMH-like superfamily | Interproscan |
| IPR012675 all species → | Homologous_superfamily | Beta-grasp domain superfamily | Interproscan |
| IPR036884 all species → | Homologous_superfamily | [2Fe-2S]-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11908 all species → | XANTHINE DEHYDROGENASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0051536 all species → | Molecular Function | iron-sulfur cluster binding | Interproscan |
| GO:0016491 all species → | Molecular Function | oxidoreductase activity | Interproscan |
| GO:0071949 all species → | Molecular Function | FAD binding | Interproscan |
| GO:0005506 all species → | Molecular Function | iron ion binding | Interproscan |
| GO:0046872 all species → | Molecular Function | metal ion binding | Interproscan |
| GO:0050660 all species → | Molecular Function | flavin adenine dinucleotide binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00106 | XDH; xanthine dehydrogenase/oxidase | EC:1.17.1.4 EC:1.17.3.2 | Exosome | ko04147 | deepkoala |
Transcript abundance of XP_032242989.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 12.09 | 15.40 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 8.09 | 11.34 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 9.22 | 10.30 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 8.71 | 10.33 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 8.33 | 9.87 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 2 | 6.49 | 9.93 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 2 | 7.69 | 12.64 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 7.17 | 7.94 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 3 | 6.71 | 7.29 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 6.56 | 7.57 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 7.35 | 8.92 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 9.57 | 10.36 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 9.03 | 9.94 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 1 | 3.46 | 10.37 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 12.10 | 13.58 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 3.08 | 9.24 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.