Detailed information of XP_032242989.2 in Nematostella vectensis

Genomic Location: NC_064036.1:1267252...1302612
NR annotation: XP_032242989.2, xanthine dehydrogenase/oxidase-like [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P47989Xanthine dehydrogenase/oxidase OS=Homo sapiens OX=9606 GN=XDH PE=1 SV=4
P47990Xanthine dehydrogenase/oxidase OS=Gallus gallus OX=9031 GN=XDH PE=1 SV=1
P22985Xanthine dehydrogenase/oxidase OS=Rattus norvegicus OX=10116 GN=Xdh PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001251 (this species only)

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF20256
all species →
MoCoBD_2Molybdopterin cofactor-binding domainDomainInterproscan
PF00111
all species →
Fer22Fe-2S iron-sulfur cluster binding domainDomainInterproscan
PF01315
all species →
Ald_Xan_dh_CAldehyde oxidase and xanthine dehydrogenase, a/b hammerhead domainDomainInterproscan
PF00941
all species →
FAD_binding_5FAD binding domain in molybdopterin dehydrogenaseFamilyInterproscan
PF02738
all species →
MoCoBD_1Molybdopterin cofactor-binding domainDomainInterproscan
PF03450
all species →
CO_deh_flav_CCO dehydrogenase flavoprotein C-terminal domainDomainInterproscan
PF01799
all species →
Fer2_2[2Fe-2S] binding domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR046867
all species →
DomainAldehyde oxidase/xanthine dehydrogenase, second molybdopterin binding domainInterproscan
IPR036683
all species →
Homologous_superfamilyCO dehydrogenase flavoprotein, C-terminal domain superfamilyInterproscan
IPR016167
all species →
Homologous_superfamilyFAD-binding, type PCMH, subdomain 1Interproscan
IPR001041
all species →
Domain2Fe-2S ferredoxin-type iron-sulfur binding domainInterproscan
IPR036856
all species →
Homologous_superfamilyAldehyde oxidase/xanthine dehydrogenase, a/b hammerhead superfamilyInterproscan
IPR000674
all species →
DomainAldehyde oxidase/xanthine dehydrogenase, a/b hammerheadInterproscan
IPR002346
all species →
DomainMolybdopterin dehydrogenase, FAD-bindingInterproscan
IPR008274
all species →
DomainAldehyde oxidase/xanthine dehydrogenase, first molybdopterin binding domainInterproscan
IPR037165
all species →
Homologous_superfamilyAldehyde oxidase/xanthine dehydrogenase, molybdopterin binding domain superfamilyInterproscan
IPR016169
all species →
Homologous_superfamilyFAD-binding, type PCMH, subdomain 2Interproscan
IPR016166
all species →
DomainFAD-binding domain, PCMH-typeInterproscan
IPR005107
all species →
DomainCO dehydrogenase flavoprotein, C-terminalInterproscan
IPR016208
all species →
FamilyAldehyde oxidase/xanthine dehydrogenase-likeInterproscan
IPR002888
all species →
Domain[2Fe-2S]-bindingInterproscan
IPR036010
all species →
Homologous_superfamily2Fe-2S ferredoxin-like superfamilyInterproscan
IPR036318
all species →
Homologous_superfamilyFAD-binding, type PCMH-like superfamilyInterproscan
IPR012675
all species →
Homologous_superfamilyBeta-grasp domain superfamilyInterproscan
IPR036884
all species →
Homologous_superfamily[2Fe-2S]-binding domain superfamilyInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11908
all species →
XANTHINE DEHYDROGENASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0051536
all species →
Molecular Functioniron-sulfur cluster bindingInterproscan
GO:0016491
all species →
Molecular Functionoxidoreductase activityInterproscan
GO:0071949
all species →
Molecular FunctionFAD bindingInterproscan
GO:0005506
all species →
Molecular Functioniron ion bindingInterproscan
GO:0046872
all species →
Molecular Functionmetal ion bindingInterproscan
GO:0050660
all species →
Molecular Functionflavin adenine dinucleotide bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K00106XDH; xanthine dehydrogenase/oxidaseEC:1.17.1.4
EC:1.17.3.2
Exosomeko04147deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032242989.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
42TPM > 0
16Conditions
15.4Max TPM
7.9Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole 6 week old aboral regenerate · regenerate 96hpa 3 3 12.09 15.40
whole 6 week old aboral regenerate · regenerate 144hpa 3 3 8.09 11.34
whole 6 week old aboral regenerate · regenerate 0hpa 3 3 9.22 10.30
whole 6 week old aboral regenerate · regenerate 2hpa 3 3 8.71 10.33
whole 6 week old aboral regenerate · regenerate uncut 3 3 8.33 9.87
whole 6 week old aboral regenerate · regenerate 4hpa 3 2 6.49 9.93
whole 6 week old aboral regenerate · regenerate 120hpa 3 2 7.69 12.64
whole 6 week old aboral regenerate · regenerate 36hpa 3 3 7.17 7.94
whole 6 week old aboral regenerate · regenerate 24hpa 3 3 6.71 7.29
whole 6 week old aboral regenerate · regenerate 20hpa 3 3 6.56 7.57
whole 6 week old aboral regenerate · regenerate 16hpa 3 3 7.35 8.92
whole 6 week old aboral regenerate · regenerate 72hpa 3 3 9.57 10.36
whole 6 week old aboral regenerate · regenerate 60hpa 3 3 9.03 9.94
whole 6 week old aboral regenerate · regenerate 48hpa 3 1 3.46 10.37
whole 6 week old aboral regenerate · regenerate 8hpa 3 3 12.10 13.58
whole 6 week old aboral regenerate · regenerate 12hpa 3 1 3.08 9.24

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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