Detailed information of XP_032243302.2 in Nematostella vectensis

Genomic Location: NC_064034.1:11737891...11754900
NR annotation: XP_032243301.2, histone-lysine N-methyltransferase, H3 lysine-79 specific isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q8TEK3Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Homo sapiens OX=9606 GN=DOT1L PE=1 SV=3
Q8INR6Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Drosophila melanogaster OX=7227 GN=gpp PE=1 SV=2
Q6AW06Histone-lysine N-methyltransferase, H3 lysine-79 specific OS=Caenorhabditis elegans OX=6239 GN=dot-1.1 PE=1 SV=2
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0005416 (this species only)

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF08123
all species →
DOT1Histone methylation protein DOT1 DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR029063
all species →
Homologous_superfamilyS-adenosyl-L-methionine-dependent methyltransferase superfamilyInterproscan
IPR025789
all species →
DomainHistone-lysine N-methyltransferase DOT1 domainInterproscan
IPR030445
all species →
FamilyHistone H3-K79 methyltransferaseInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR21451
all species →
HISTONE H3 METHYLTRANSFERASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0031151
all species →
Molecular Functionhistone H3K79 methyltransferase activityInterproscan
GO:0000077
all species →
Biological ProcessDNA damage checkpoint signalingInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0006281
all species →
Biological ProcessDNA repairInterproscan
GO:0051726
all species →
Biological Processregulation of cell cycleInterproscan
GO:2000677
all species →
Biological Processregulation of transcription regulatory region DNA bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K11427DOT1L, DOT1; [histone H3]-lysine79 N-trimethyltransferaseEC:2.1.1.360
Chromosome and associated proteinsko03036deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032243302.2 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples
45TPM > 0
16Conditions
23.9Max TPM
16.2Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
whole 6 week old aboral regenerate · regenerate 96hpa 3 3 20.57 23.81
whole 6 week old aboral regenerate · regenerate 144hpa 3 3 15.42 21.27
whole 6 week old aboral regenerate · regenerate 0hpa 3 3 17.46 19.64
whole 6 week old aboral regenerate · regenerate 2hpa 3 3 21.31 23.56
whole 6 week old aboral regenerate · regenerate uncut 3 3 15.36 16.91
whole 6 week old aboral regenerate · regenerate 4hpa 3 2 11.47 17.65
whole 6 week old aboral regenerate · regenerate 120hpa 3 3 21.14 23.92
whole 6 week old aboral regenerate · regenerate 36hpa 3 3 16.41 18.97
whole 6 week old aboral regenerate · regenerate 24hpa 3 3 14.96 19.98
whole 6 week old aboral regenerate · regenerate 20hpa 3 3 15.45 18.74
whole 6 week old aboral regenerate · regenerate 16hpa 3 3 14.94 16.79
whole 6 week old aboral regenerate · regenerate 72hpa 3 3 18.63 22.00
whole 6 week old aboral regenerate · regenerate 60hpa 3 3 18.74 21.54
whole 6 week old aboral regenerate · regenerate 48hpa 3 2 13.05 22.48
whole 6 week old aboral regenerate · regenerate 8hpa 3 3 15.23 19.23
whole 6 week old aboral regenerate · regenerate 12hpa 3 2 8.84 17.53

Per sample · hover a bar for the full sample record · show / hide the sample table

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

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