Gene detail

Detailed information of XP_032243341.1 in Nematostella vectensis

Genomic Location: NC_064034.1:11132789...11138443
NR annotation: XP_032243341.1, serine/threonine-protein kinase STK11 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_032387450.2

TGACGTCATAGCAGCGGTGTGACGTAAACCAAGATGGTGGCTGTTATTGAGTCGAGAGAGAGGGGAGCTTTGCCTCATCCCACTAGCTGAAAAATCTAATCTTGGATGGTTCCTGCCTCTTTCCCTACGTCCCCAAATGGTGGACAGTATGGTAGCTGGCAATGGAGGTCAGCCGCAGTTCATTATGGGTGGATCGAGCCCCGATGAAAACGACTTGGACGTGAACCCCTTAGCTCATTTCTCTTCTCCTCCGTGGCTCGAGAACGATGACCCTACGATTATATTCCATCGCGTTAATTCCGACCAAATAATTTATTCTCCGCGTGCAAAGCGAGCTAAACTTGTCGGAAAATATTTGATGGGAGACATGCTTGGAGAAGGCTCCTATGGAAAGGTCAAGGAAATGTTAGATTGTGAGAACCTTCGGAGGTGTGCTgtcaaaattttgaaaaagcgACGGTTAAGACGAATACCTAACGGCGAGCAAAATGTAAAAAGGGAAATTCGTTTACTTAAGCGTTTGAATCATAAAAATGTTATACAGCTTTATGATGTTATTTACGAcgaagtaaaacaaaaaatGTATATGATATTTGAGTATTGTGTGGGTGAGTTACAAGAGATGCTGGAAAGTGTTGATGACCGCAAGTTTCCAATATCTCAAGCACATGGGTACTTTTGCCAGTTGATGGATGGCCTAAAGTATCTTCATTGTCAAGGCGTTGTACATAAAGATATCAAGCCAAGTAACCTACTCTTGTCTACAGATGGCACTCTGAAGATTTCTGATCTAGGCGTTGCAGAGAGACTCAGTCCATTCAGTGCAGATGACACTTGTCGCACTAGTCAAGGATCACCAGCCTTTCAACCTCCTGAGATAGCTAATGGGCTTGAGACCTTCTCAGGGTTTAAAGTGGATATATGGGCTGCAGGGGTTACACTATACAATATAACAACAGGGAAATACCCTTTCGAAGGTGACAATATATACAGGCTATTTGAGAATATTGGCAAAGGGGAATTCTCAATCCCTGATGAAGTAGATGATTCTTTATCCGACTTATTAAAAGGTATGCTGAATCCAGATCCTGAGAAAAGACTCACTATCGAGCAAATACGAAACCACAGATGGGTGATAAAGACCCACCCTCTACCTCGTGATCCTGTGGCTATCCCTCCTCTCGGTGGGGATGAGGTGCGGGGGATGACAGTCATTCCATATCTAGAGGACCTGCATAGCTCTTCGGAGCACCTCAACCAAGAGGGTGAATCGACTGATGACCTAAAATTAACTGTTTCTGAATCAAGCAAGAAAAAGTCCAAGCTCAAAAGGCCAAGCTTTGGTTCTTGTCGGACGCAATGACATCTTTCACTTCAATTTATACAGTCAGTGGCTATATGGCTAGAAATATGGGCATGTCGTTCAGTCAAGAAAATGTttcataaaaatcatttccATGCTTGTAATACTGCACTTATATATACTATTTTCACTACTCAAATGAAGCTGTAAGATAATTTATCCAAATAATACATTTTGGTGTCAAAACTTCTTCTTAGTGTCAGACGTTCCCTCCCTACAAGATGAGTGTGACAGTAAGAGCAATAATAAGCAGACACTATGTTTGCCAAGGCTCTGATAAAATTTGAAACatgttcttgttattttttaaagtgaaactttaaatttattttaatatttgatGTTCAATTATTGTATGAAGGCATTGTAACCTTCTGTCTGGATAACGCGAATTTCAGCTTTTGGAGGTGGAAGTTACTTGGAAAATGTTACAATAAAACCATACTTTTCCTTCAGCCACAACATGTTACCCTTGGATCCTACATCGGGTAGGTACGTTATATATGATACATAGTAATGAACCGACAACAGAATgtcaaaagaacaaagaaagtATGGATAAACGAAAGTctaaagaacaatagaattaCATTTCAGAACAATATATAATATCATATATAATGTACCTACCCTAAATCAAGACCAGAGACCCCTTTGGATTTTTTGCAGCTTTTGTTCATAATACTTCTCTACCAACTTTCTTAATACTTTTAAATACACATCTTATTCAAATCATGATCACTCAAGAAACAATGTAAAATACAGTATCCACATTTTGAGGGGAATCAAGTTGTTTCGACACAGTAACGTTTGAAGAAACATATGAATGAACTACTTTTAAATGTAGGGAAAAGAAATTTTTTCTCAGGAAatttatttgtaaatataaaaaaaaattatatgacATTATATGTTTCTTTCAGTTGAAAGCTGTAGCCTGTTACAGGTTGCATAATGTAAGGTCCATCTAatatacaatttttttatgaGCTCCATATGcaaatgttattttatttggagTGGGTCTTTAAGTTCTGATGACTAGATGAACATATATAATACTTTCTTTGCTTTTATTGTGTAACAATACAAAGAATAGGGAAAAGCCTTTTTATCTAATAGTAGTGTTGAATTTTCTTCCTCTATTCCCTACTCTTACtccaataaagtatttttttgttga

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q15831	Serine/threonine-protein kinase STK11 OS=Homo sapiens OX=9606 GN=STK11 PE=1 SV=1
Q91604	Serine/threonine-protein kinase stk11 OS=Xenopus laevis OX=8355 GN=stk11 PE=1 SV=1
Q0GGW5	Serine/threonine-protein kinase STK11 OS=Gallus gallus OX=9031 GN=STK11 PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0003513 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR039154 all species →	Domain	Serine/Threonine kinase LKB1, catalytic domain	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24346 all species →	MAP/MICROTUBULE AFFINITY-REGULATING KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0004674 all species →	Molecular Function	protein serine/threonine kinase activity	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0035556 all species →	Biological Process	intracellular signal transduction	Interproscan
GO:0001558 all species →	Biological Process	regulation of cell growth	Interproscan
GO:0030010 all species →	Biological Process	establishment of cell polarity	Interproscan
GO:0030295 all species →	Molecular Function	protein kinase activator activity	Interproscan
GO:0042593 all species →	Biological Process	glucose homeostasis	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K07298	STK11, LKB1; serine/threonine-protein kinase 11	EC:2.7.11.1	Protein kinases	ko01001	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_032243341.1 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

48Samples

41TPM > 0

16Conditions

25.0Max TPM

13.2Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM
whole 6 week old aboral regenerate · regenerate 96hpa	3	3	14.68	17.63
whole 6 week old aboral regenerate · regenerate 144hpa	3	3	10.03	12.81
whole 6 week old aboral regenerate · regenerate 0hpa	3	3	11.24	12.87
whole 6 week old aboral regenerate · regenerate 2hpa	3	3	23.04	25.01
whole 6 week old aboral regenerate · regenerate uncut	3	3	12.33	17.33
whole 6 week old aboral regenerate · regenerate 4hpa	3	2	12.72	20.02
whole 6 week old aboral regenerate · regenerate 120hpa	3	2	8.73	13.67
whole 6 week old aboral regenerate · regenerate 36hpa	3	3	16.56	22.29
whole 6 week old aboral regenerate · regenerate 24hpa	3	3	18.81	21.13
whole 6 week old aboral regenerate · regenerate 20hpa	3	3	16.88	17.53
whole 6 week old aboral regenerate · regenerate 16hpa	3	3	17.03	21.75
whole 6 week old aboral regenerate · regenerate 72hpa	3	2	8.94	15.37
whole 6 week old aboral regenerate · regenerate 60hpa	3	3	13.44	14.27
whole 6 week old aboral regenerate · regenerate 48hpa	3	2	10.27	18.40
whole 6 week old aboral regenerate · regenerate 8hpa	3	2	8.94	14.31
whole 6 week old aboral regenerate · regenerate 12hpa	3	1	6.95	20.85

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR6320863	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	17.63
SRR6320836	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	14.04
SRR6320837	whole 6 week old aboral regenerate · regenerate 96hpa	whole 6 week old aboral regenerate	six weeks	regenerate 96hpa	SRP125570	12.36
SRR6320847	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	12.81
SRR6320838	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	9.02
SRR6320841	whole 6 week old aboral regenerate · regenerate 144hpa	whole 6 week old aboral regenerate	six weeks	regenerate 144hpa	SRP125570	8.26
SRR6320846	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	12.87
SRR6320840	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	11.47
SRR6320839	whole 6 week old aboral regenerate · regenerate 0hpa	whole 6 week old aboral regenerate	six weeks	regenerate 0hpa	SRP125570	9.38
SRR6320861	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	25.01
SRR6320842	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	22.59
SRR6320848	whole 6 week old aboral regenerate · regenerate 2hpa	whole 6 week old aboral regenerate	six weeks	regenerate 2hpa	SRP125570	21.52
SRR6320843	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	17.33
SRR6320844	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	10.76
SRR6320845	whole 6 week old aboral regenerate · regenerate uncut	whole 6 week old aboral regenerate	six weeks	regenerate uncut	SRP125570	8.89
SRR6320872	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	20.02
SRR6320849	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	18.14
SRR6320873	whole 6 week old aboral regenerate · regenerate 4hpa	whole 6 week old aboral regenerate	six weeks	regenerate 4hpa	SRP125570	0.00
SRR6320882	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	13.67
SRR6320883	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	12.53
SRR6320850	whole 6 week old aboral regenerate · regenerate 120hpa	whole 6 week old aboral regenerate	six weeks	regenerate 120hpa	SRP125570	0.00
SRR6320855	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	22.29
SRR6320851	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	15.66
SRR6320852	whole 6 week old aboral regenerate · regenerate 36hpa	whole 6 week old aboral regenerate	six weeks	regenerate 36hpa	SRP125570	11.74
SRR6320854	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	21.13
SRR6320856	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	20.76
SRR6320853	whole 6 week old aboral regenerate · regenerate 24hpa	whole 6 week old aboral regenerate	six weeks	regenerate 24hpa	SRP125570	14.55
SRR6320857	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	17.53
SRR6320859	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	16.63
SRR6320860	whole 6 week old aboral regenerate · regenerate 20hpa	whole 6 week old aboral regenerate	six weeks	regenerate 20hpa	SRP125570	16.49
SRR6320880	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	21.75
SRR6320881	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	15.28
SRR6320858	whole 6 week old aboral regenerate · regenerate 16hpa	whole 6 week old aboral regenerate	six weeks	regenerate 16hpa	SRP125570	14.05
SRR6320862	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	15.37
SRR6320865	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	11.44
SRR6320864	whole 6 week old aboral regenerate · regenerate 72hpa	whole 6 week old aboral regenerate	six weeks	regenerate 72hpa	SRP125570	0.00
SRR6320869	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	14.27
SRR6320867	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	13.16
SRR6320866	whole 6 week old aboral regenerate · regenerate 60hpa	whole 6 week old aboral regenerate	six weeks	regenerate 60hpa	SRP125570	12.90
SRR6320870	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	18.40
SRR6320871	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	12.41
SRR6320868	whole 6 week old aboral regenerate · regenerate 48hpa	whole 6 week old aboral regenerate	six weeks	regenerate 48hpa	SRP125570	0.00
SRR6320874	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	14.31
SRR6320875	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	12.51
SRR6320876	whole 6 week old aboral regenerate · regenerate 8hpa	whole 6 week old aboral regenerate	six weeks	regenerate 8hpa	SRP125570	0.00
SRR6320877	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	20.85
SRR6320878	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00
SRR6320879	whole 6 week old aboral regenerate · regenerate 12hpa	whole 6 week old aboral regenerate	six weeks	regenerate 12hpa	SRP125570	0.00

Source: CnidoSite RNA-seq expression matrices (NVECT_TPM, StringTie quantification over 48 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.