Detailed information of XP_044183458.1 in Acropora millepora

Genomic Location: NC_058076.1:5046814...5078446
NR annotation: XP_044183458.1, C-1-tetrahydrofolate synthase, cytoplasmic-like [Acropora millepora]


 Gene Structure
More details in Jbrowse  Sequence
CDS
Transcript
Protein
 Uniprot
Uniprot termDescription
P11586C-1-tetrahydrofolate synthase, cytoplasmic OS=Homo sapiens OX=9606 GN=MTHFD1 PE=1 SV=4
Q922D8C-1-tetrahydrofolate synthase, cytoplasmic OS=Mus musculus OX=10090 GN=Mthfd1 PE=1 SV=4
P27653C-1-tetrahydrofolate synthase, cytoplasmic OS=Rattus norvegicus OX=10116 GN=Mthfd1 PE=1 SV=3

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF02882THF_DHG_CYH_CTetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domainDomainInterproscan
PF00763THF_DHG_CYHTetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domainDomainInterproscan
PF01268FTHFSFormate--tetrahydrofolate ligaseFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR020631DomainTetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domainInterproscan
IPR027417Homologous_superfamilyP-loop containing nucleoside triphosphate hydrolaseInterproscan
IPR020628Conserved_siteFormate-tetrahydrofolate ligase, FTHFS, conserved siteInterproscan
IPR020867Conserved_siteTetrahydrofolate dehydrogenase/cyclohydrolase, conserved siteInterproscan
IPR000672FamilyTetrahydrofolate dehydrogenase/cyclohydrolaseInterproscan
IPR020630DomainTetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domainInterproscan
IPR036291Homologous_superfamilyNAD(P)-binding domain superfamilyInterproscan
IPR046346Homologous_superfamilyAminoacid dehydrogenase-like, N-terminal domain superfamilyInterproscan
IPR000559FamilyFormate-tetrahydrofolate ligase, FTHFSInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR48099C-1-TETRAHYDROFOLATE SYNTHASE, CYTOPLASMIC-RELATEDInterproscan

 Gene Ontology
GO termsCategoryDescriptionSource
GO:0004488Molecular Functionmethylenetetrahydrofolate dehydrogenase (NADP+) activityInterproscan
GO:0004477Molecular Functionmethenyltetrahydrofolate cyclohydrolase activityInterproscan
GO:0005829Cellular ComponentcytosolInterproscan
GO:0035999Biological Processtetrahydrofolate interconversionInterproscan
GO:0005524Molecular FunctionATP bindingInterproscan
GO:0003824Molecular Functioncatalytic activityInterproscan
GO:0004329Molecular Functionformate-tetrahydrofolate ligase activityInterproscan

 KEGG pathway
KOEnzymeEnzyme IDpathwaymapIDSource
K00288MTHFD; methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetaseEC:1.5.1.5
EC:3.5.4.9
EC:6.3.4.3
Exosomeko04147deepkoala

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