Genomic Location: NC_064046.1:1124580...1167117
NR annotation: XP_048577151.1, F-actin-uncapping protein LRRC16A isoform X5 [Nematostella vectensis]
| CDS | |||||
| LOC5521508 | |||||
| Transcript |
| rna-XM_048721194.1 |
| Protein |
| XP_048577151.1 |
| Uniprot term | Description |
|---|---|
| Q5VZK9 | F-actin-uncapping protein LRRC16A OS=Homo sapiens OX=9606 GN=CARMIL1 PE=1 SV=1 |
| Q6EDY6 | F-actin-uncapping protein LRRC16A OS=Mus musculus OX=10090 GN=Carmil1 PE=1 SV=2 |
| Q5XHY1 | Capping protein, Arp2/3 and myosin-I linker protein 3 OS=Rattus norvegicus OX=10116 GN=Carmil3 PE=2 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13516 | LRR_6 | Leucine Rich repeat | Repeat | Interproscan |
| PF16000 | CARMIL_C | CARMIL C-terminus | Family | Interproscan |
| PF17888 | Carm_PH | Carmil pleckstrin homology domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001611 | Repeat | Leucine-rich repeat | Interproscan |
| IPR031943 | Domain | CARMIL, C-terminal domain | Interproscan |
| IPR041245 | Domain | CARMIL, pleckstrin homology domain | Interproscan |
| IPR032675 | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR051279 | Family | Protein Phosphatase 1 Regulatory and Actin Interaction Protein | Interproscan |
| IPR011993 | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR24112 | LEUCINE-RICH REPEAT, ISOFORM F-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0005886 | Cellular Component | plasma membrane | Interproscan |
| GO:0016477 | Biological Process | cell migration | Interproscan |
| GO:0030027 | Cellular Component | lamellipodium | Interproscan |
| GO:0034315 | Biological Process | regulation of Arp2/3 complex-mediated actin nucleation | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K20493 | LRRC16, CARMIL; leucine-rich repeat-containing protein 16 | - | Membrane trafficking | ko04131 | deepkoala |