Genomic Location: NC_064047.1:8708561...8733601
NR annotation: XP_048577331.1, cytochrome b5 reductase 4-like isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC116617145 |
| Transcript |
| rna-XM_048721374.1 |
| Protein |
| XP_048577331.1 |
| UniProt accession | Description |
|---|---|
| Q28CZ9 | Cytochrome b5 reductase 4 OS=Xenopus tropicalis OX=8364 GN=cyb5r4 PE=2 SV=1 |
| Q68EJ0 | Cytochrome b5 reductase 4 OS=Rattus norvegicus OX=10116 GN=Cyb5r4 PE=1 SV=2 |
| Q7L1T6 | Cytochrome b5 reductase 4 OS=Homo sapiens OX=9606 GN=CYB5R4 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004279 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00175 all species → | NAD_binding_1 | Oxidoreductase NAD-binding domain | Domain | Interproscan |
| PF00173 all species → | Cyt-b5 | Cytochrome b5-like Heme/Steroid binding domain | Domain | Interproscan |
| PF00970 all species → | FAD_binding_6 | Oxidoreductase FAD-binding domain | Domain | Interproscan |
| PF04969 all species → | CS | CS domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001199 all species → | Domain | Cytochrome b5-like heme/steroid binding domain | Interproscan |
| IPR018506 all species → | Binding_site | Cytochrome b5, heme-binding site | Interproscan |
| IPR037908 all species → | Domain | Cytochrome b5 reductase 4, p23 domain | Interproscan |
| IPR001433 all species → | Domain | Oxidoreductase FAD/NAD(P)-binding | Interproscan |
| IPR008978 all species → | Homologous_superfamily | HSP20-like chaperone | Interproscan |
| IPR001834 all species → | Family | NADH:cytochrome b5 reductase-like | Interproscan |
| IPR008333 all species → | Domain | Flavoprotein pyridine nucleotide cytochrome reductase-like, FAD-binding domain | Interproscan |
| IPR017938 all species → | Homologous_superfamily | Riboflavin synthase-like beta-barrel | Interproscan |
| IPR036400 all species → | Homologous_superfamily | Cytochrome b5-like heme/steroid binding domain superfamily | Interproscan |
| IPR039261 all species → | Homologous_superfamily | Ferredoxin-NADP reductase (FNR), nucleotide-binding domain | Interproscan |
| IPR017927 all species → | Domain | FAD-binding domain, ferredoxin reductase-type | Interproscan |
| IPR007052 all species → | Domain | CS domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR19370 all species → | NADH-CYTOCHROME B5 REDUCTASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0020037 all species → | Molecular Function | heme binding | Interproscan |
| GO:0016491 all species → | Molecular Function | oxidoreductase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00326 | CYB5R; cytochrome-b5 reductase | EC:1.6.2.2 | Amino sugar and nucleotide sugar metabolism | ko00520 | deepkoala |
Transcript abundance of XP_048577331.1 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 7.27 | 9.85 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 8.29 | 12.66 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 8.81 | 10.92 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 10.43 | 12.28 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 9.66 | 12.40 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 1 | 3.70 | 11.11 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 2 | 7.28 | 12.39 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 8.02 | 9.08 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 6.27 | 11.59 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 10.94 | 12.74 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 8.28 | 9.26 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 11.87 | 18.40 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 9.87 | 11.09 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 1 | 3.30 | 9.91 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 2 | 6.83 | 10.99 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 3.24 | 9.73 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
