Genomic Location: NC_064047.1:13198368...13239987
NR annotation: XP_048578065.1, inositol polyphosphate 5-phosphatase OCRL isoform X1 [Nematostella vectensis]
| CDS | |||||
| LOC5503077 | |||||
| Transcript |
| rna-XM_048722109.1 |
| Protein |
| XP_048578066.1 |
| Uniprot term | Description |
|---|---|
| D3ZGS3 | Inositol polyphosphate 5-phosphatase OCRL OS=Rattus norvegicus OX=10116 GN=Ocrl PE=1 SV=1 |
| Q01968 | Inositol polyphosphate 5-phosphatase OCRL OS=Homo sapiens OX=9606 GN=OCRL PE=1 SV=3 |
| Q6NVF0 | Inositol polyphosphate 5-phosphatase OCRL OS=Mus musculus OX=10090 GN=Ocrl PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21310 | OCRL-like_ASH | Inositol polyphosphate 5-phosphatase OCRL-like, ASH domain | Domain | Interproscan |
| PF16776 | INPP5B_PH | Type II inositol 1,4,5-trisphosphate 5-phosphatase PH domain | Domain | Interproscan |
| PF00620 | RhoGAP | RhoGAP domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036691 | Homologous_superfamily | Endonuclease/exonuclease/phosphatase superfamily | Interproscan |
| IPR048869 | Domain | OCRL-1/2, ASH domain | Interproscan |
| IPR037793 | Domain | OCRL1/INPP5B, INPP5c domain | Interproscan |
| IPR000300 | Domain | Inositol polyphosphate-related phosphatase | Interproscan |
| IPR000198 | Domain | Rho GTPase-activating protein domain | Interproscan |
| IPR031896 | Domain | INPP5B, PH domain | Interproscan |
| IPR008936 | Homologous_superfamily | Rho GTPase activation protein | Interproscan |
| IPR013783 | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR047078 | Domain | Inositol polyphosphate 5-phosphatase OCRL, RhoGAP | Interproscan |
| IPR046985 | Family | Inositol 5-phosphatase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11200 | INOSITOL 5-PHOSPHATASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0052745 | Molecular Function | inositol phosphate phosphatase activity | Interproscan |
| GO:0016791 | Molecular Function | phosphatase activity | Interproscan |
| GO:0046856 | Biological Process | phosphatidylinositol dephosphorylation | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0004439 | Molecular Function | phosphatidylinositol-4,5-bisphosphate 5-phosphatase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K01099 | INPP5B_F; inositol polyphosphate 5-phosphatase INPP5B/F | EC:3.1.3.36 | Membrane trafficking | ko04131 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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