Genomic Location: NC_064035.1:6899232...6925982
NR annotation: XP_048579848.1, 1-phosphatidylinositol 3-phosphate 5-kinase isoform X1 [Nematostella vectensis]
| CDS | |||||
| LOC5517971 | |||||
| Transcript |
| rna-XM_048723891.1 |
| Protein |
| XP_048579848.1 |
| Uniprot term | Description |
|---|---|
| Q9Z1T6 | 1-phosphatidylinositol 3-phosphate 5-kinase OS=Mus musculus OX=10090 GN=Pikfyve PE=1 SV=3 |
| Q9Y2I7 | 1-phosphatidylinositol 3-phosphate 5-kinase OS=Homo sapiens OX=9606 GN=PIKFYVE PE=1 SV=3 |
| O96838 | Putative 1-phosphatidylinositol 3-phosphate 5-kinase OS=Drosophila melanogaster OX=7227 GN=fab1 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01363 | FYVE | FYVE zinc finger | Domain | Interproscan |
| PF00610 | DEP | Domain found in Dishevelled, Egl-10, and Pleckstrin (DEP) | Domain | Interproscan |
| PF00118 | Cpn60_TCP1 | TCP-1/cpn60 chaperonin family | Family | Interproscan |
| PF01504 | PIP5K | Phosphatidylinositol-4-phosphate 5-Kinase | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR000591 | Domain | DEP domain | Interproscan |
| IPR002498 | Domain | Phosphatidylinositol-4-phosphate 4/5-kinase, core | Interproscan |
| IPR027484 | Homologous_superfamily | Phosphatidylinositol-4-phosphate 5-kinase, N-terminal | Interproscan |
| IPR044769 | Domain | 1-phosphatidylinositol-3-phosphate 5-kinase, PIPK catalytic domain | Interproscan |
| IPR017455 | Domain | Zinc finger, FYVE-related | Interproscan |
| IPR027409 | Homologous_superfamily | GroEL-like apical domain superfamily | Interproscan |
| IPR000306 | Domain | FYVE zinc finger | Interproscan |
| IPR027483 | Homologous_superfamily | Phosphatidylinositol-4-phosphate 4/5-kinase, C-terminal domain superfamily | Interproscan |
| IPR036390 | Homologous_superfamily | Winged helix DNA-binding domain superfamily | Interproscan |
| IPR013083 | Homologous_superfamily | Zinc finger, RING/FYVE/PHD-type | Interproscan |
| IPR002423 | Family | Chaperonin Cpn60/GroEL/TCP-1 family | Interproscan |
| IPR011011 | Homologous_superfamily | Zinc finger, FYVE/PHD-type | Interproscan |
| IPR036388 | Homologous_superfamily | Winged helix-like DNA-binding domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45748 | 1-PHOSPHATIDYLINOSITOL 3-PHOSPHATE 5-KINASE-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0035556 | Biological Process | intracellular signal transduction | Interproscan |
| GO:0046488 | Biological Process | phosphatidylinositol metabolic process | Interproscan |
| GO:0052742 | Molecular Function | phosphatidylinositol kinase activity | Interproscan |
| GO:0000285 | Molecular Function | 1-phosphatidylinositol-3-phosphate 5-kinase activity | Interproscan |
| GO:0046872 | Molecular Function | metal ion binding | Interproscan |
| GO:0010008 | Cellular Component | endosome membrane | Interproscan |
| GO:0046854 | Biological Process | phosphatidylinositol phosphate biosynthetic process | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K00921 | PIKFYVE, FAB1; 1-phosphatidylinositol-3-phosphate 5-kinase | EC:2.7.1.150 | Membrane trafficking | ko04131 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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