Gene detail

Detailed information of XP_048579988.1 in Nematostella vectensis

Genomic Location: NC_064035.1:1846518...1850894
NR annotation: XP_048579988.1, serine/threonine-protein kinase Nek8 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

LOC116601992

ATGCAGAACTACGAGAAAGTCCGGATCGTCGGCCGTGGCGCCTACGGGACGGTGTACTTGTGCCGACGATTAGTCGATAACTTTCTCGTCATTATCAAGCAAATTCCAGTTGAAGAAATGACAAAAGAAGAGCGTCAATCTGCCTTAAATGAAGTTAAGGTGCTCTCGATGTTCCAACACCCAAATATAATTCGTTATTACGACAGTTTCGTACAGGAAAAAGCACTGATGATCGTAATGGAGTACGCCCAAGGGGGGACTATCTACGACTATCTTCAACAGCGAGGAGGGAAATTGATGGACGAAGACGAAATACTGCGACTTTTTGTGCAAATCCTGTTAGCCCTTCGACATGTTCACAAGGGTCAAATCCTACACAGGGACCTTAAAACACAAAATATCCTACTAAATAAGAAACGAAAGGTTGTGAAAATAGGGGACTTTGGTATTTCTAAGATTCTCAGCAGTAAGAGCAAAGCAAATACGGTAATTGGGTCTCCGTGTTATATCTCCCCTGAGTTATGTGAGGGAAAGCCATACAACCAGAAAAGTGATGTTTGGTCACTCGGTTGTGTCCTTTATGAGCTTACCACCTTAAAGCGAGCGTTCGAGGCATCTAACCTCCCAGCACTAGTGTTAAAGATAATGCGAGGGTACTTCTCACCAATACCTGAGAGGTACAGTGAGGAGTTGCGTAAACTAATCCTGGACATGCTGGTACTGGATCCAACCAAAAGACCAGGTATCAAGGAAATTATGGCCCAACCTGTTATTGTCAATGCATTGTTTGACTTGCCAACAGATGTTGGCCGAGTGCCATGTACACGGTTCCCTAGGACTGGAGCTGGTATTGCCGCCGCCATTCCACCATCACGCTCTAGACCATCCATTTCAACTCAGTGTAGGAGCAAGCAATTTCCAAGAACATCTTCCACAAGCTCAGCAAGCACTATACTGGAAGGGCTGCCTGAGAACCTCGGAGTATTCGCTATGAAGCCACAAGAGCCCCAGCACATGGTATACCACTGGGGCGGAGGGATAACCTACCCAAACCCTCTGCCGCTTCCCCAGCACGATTCTGGTGTTGTCCAAGTGTCATGTGGTAGGACATTGATGACGGGTGTGACCGCAAATGGTCGAATGATACTCTGGGAGGGCAGTAAGTCCAGCGGTCTGATGTCTTCTGGTGGGAAAAATGAGAAAACTGTGTGGGTACCACGTTTCCTGGAAGGCCAGTCTGGCATCACTATAACAAAGGTGTCATGCGGTGACCTCTTTACAGCTTGCCTGACAGACCGAGGAATCTTGATGACCTTCGGGAGTGGCACGTACGGGTGTCTTGGTCATGGCACAACTAACTACGTGAGCCAAGCCAAGATTGTGGAAGATCTGCTGGGCTTCGAGGTGGAGGACATCTCATGCGGATCATCGCACATCATGGCTGTAACTGCTGACCACGAGGTGTTTGCATGGGGCCGTGGCGATAACGGTCGCCTGGGGACTGGGTCGCAGCAAGAGTATTGGTCCCCCAAGGCAATTAGCCTCCCTGAAGGCATGCGCGCGCGCTCGGTCCATTGCGGCGTGGACTGCTCGTTTGCCATCACCTTAGAAAACAAGCTTCTCGCGTGTGGCAGTAACAGATGTAACAAGCTTGCCCTGGATAACGAAGATGGGCCTGTGGAAGAGGTTGCCGTGCTGCGTCAGGTTTCTGTTCCGGACTTTAATAGCGTGGGAACGTCATCTGTTGCTATGGGCACATCACATACGCTCGTGCTATTACAGAATGGCAAGTTGTACTCGTTCGGATCAAACTCTTTCGGTCAGCTAGGGTACGTACGGGAGGGCGTGTCCCGCTTCCCCCAGCTCATCGAGTCATTGAATGATGTATCATACGTCGCTTGTGGAGACACGTTTTCTGTCGCTGTTTCTTCTGACAGTGAGGTGTTTGTCTGGGGAAAGGGGGCCAGGGGTCGCCTAGGTAACAAAGCAGACGAGGACGTCAGAGAACCCGTCTGCTTGTCGCTCCCGGCGGCGGTCCAAGTGTTATCGGTCTCTTGCAGCAACAGCGGCACGCTACTTTGTGGAAAGAAACTGTGA

Transcript

rna-XM_048724031.1

TAAGTGTTTTTACCCTGCAATAATGGCATTTTATCCACTTTTGTGTGACGTCTCTCCCCTCCCATAGTATagttttggtaaaaaaaaaggggTTGAATGTTGCTCGGAATAACAGTACCCGATAACAGTGCCTCAATGTAATTTCTAAAATCGCCACATTGACTTGAGAGTAAAGCTCGCCGGATCTGTGATGCAGAACTACGAGAAAGTCCGGATCGTCGGCCGTGGCGCCTACGGGACGGTGTACTTGTGCCGACGATTAGTCGATAACTTTCTCGTCATTATCAAGCAAATTCCAGTTGAAGAAATGACAAAAGAAGAGCGTCAATCTGCCTTAAATGAAGTTAAGGTGCTCTCGATGTTCCAACACCCAAATATAATTCGTTATTACGACAGTTTCGTACAGGAAAAAGCACTGATGATCGTAATGGAGTACGCCCAAGGGGGGACTATCTACGACTATCTTCAACAGCGAGGAGGGAAATTGATGGACGAAGACGAAATACTGCGACTTTTTGTGCAAATCCTGTTAGCCCTTCGACATGTTCACAAGGGTCAAATCCTACACAGGGACCTTAAAACACAAAATATCCTACTAAATAAGAAACGAAAGGTTGTGAAAATAGGGGACTTTGGTATTTCTAAGATTCTCAGCAGTAAGAGCAAAGCAAATACGGTAATTGGGTCTCCGTGTTATATCTCCCCTGAGTTATGTGAGGGAAAGCCATACAACCAGAAAAGTGATGTTTGGTCACTCGGTTGTGTCCTTTATGAGCTTACCACCTTAAAGCGAGCGTTCGAGGCATCTAACCTCCCAGCACTAGTGTTAAAGATAATGCGAGGGTACTTCTCACCAATACCTGAGAGGTACAGTGAGGAGTTGCGTAAACTAATCCTGGACATGCTGGTACTGGATCCAACCAAAAGACCAGGTATCAAGGAAATTATGGCCCAACCTGTTATTGTCAATGCATTGTTTGACTTGCCAACAGATGTTGGCCGAGTGCCATGTACACGGTTCCCTAGGACTGGAGCTGGTATTGCCGCCGCCATTCCACCATCACGCTCTAGACCATCCATTTCAACTCAGTGTAGGAGCAAGCAATTTCCAAGAACATCTTCCACAAGCTCAGCAAGCACTATACTGGAAGGGCTGCCTGAGAACCTCGGAGTATTCGCTATGAAGCCACAAGAGCCCCAGCACATGGTATACCACTGGGGCGGAGGGATAACCTACCCAAACCCTCTGCCGCTTCCCCAGCACGATTCTGGTGTTGTCCAAGTGTCATGTGGTAGGACATTGATGACGGGTGTGACCGCAAATGGTCGAATGATACTCTGGGAGGGCAGTAAGTCCAGCGGTCTGATGTCTTCTGGTGGGAAAAATGAGAAAACTGTGTGGGTACCACGTTTCCTGGAAGGCCAGTCTGGCATCACTATAACAAAGGTGTCATGCGGTGACCTCTTTACAGCTTGCCTGACAGACCGAGGAATCTTGATGACCTTCGGGAGTGGCACGTACGGGTGTCTTGGTCATGGCACAACTAACTACGTGAGCCAAGCCAAGATTGTGGAAGATCTGCTGGGCTTCGAGGTGGAGGACATCTCATGCGGATCATCGCACATCATGGCTGTAACTGCTGACCACGAGGTGTTTGCATGGGGCCGTGGCGATAACGGTCGCCTGGGGACTGGGTCGCAGCAAGAGTATTGGTCCCCCAAGGCAATTAGCCTCCCTGAAGGCATGCGCGCGCGCTCGGTCCATTGCGGCGTGGACTGCTCGTTTGCCATCACCTTAGAAAACAAGCTTCTCGCGTGTGGCAGTAACAGATGTAACAAGCTTGCCCTGGATAACGAAGATGGGCCTGTGGAAGAGGTTGCCGTGCTGCGTCAGGTTTCTGTTCCGGACTTTAATAGCGTGGGAACGTCATCTGTTGCTATGGGCACATCACATACGCTCGTGCTATTACAGAATGGCAAGTTGTACTCGTTCGGATCAAACTCTTTCGGTCAGCTAGGGTACGTACGGGAGGGCGTGTCCCGCTTCCCCCAGCTCATCGAGTCATTGAATGATGTATCATACGTCGCTTGTGGAGACACGTTTTCTGTCGCTGTTTCTTCTGACAGTGAGGTGTTTGTCTGGGGAAAGGGGGCCAGGGGTCGCCTAGGTAACAAAGCAGACGAGGACGTCAGAGAACCCGTCTGCTTGTCGCTCCCGGCGGCGGTCCAAGTGTTATCGGTCTCTTGCAGCAACAGCGGCACGCTACTTTGTGGAAAGAAACTGTgaagtaacgagtattgcagcacgctactttgtggagagaaactgtgaagtaacgagtattgcggcacg

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
D3ZGQ5	Serine/threonine-protein kinase Nek8 OS=Rattus norvegicus OX=10116 GN=Nek8 PE=1 SV=1
Q86SG6	Serine/threonine-protein kinase Nek8 OS=Homo sapiens OX=9606 GN=NEK8 PE=1 SV=1
Q91ZR4	Serine/threonine-protein kinase Nek8 OS=Mus musculus OX=10090 GN=Nek8 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0004216 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00069 all species →	Pkinase	Protein kinase domain	Domain	Interproscan
PF00415 all species →	RCC1	Regulator of chromosome condensation (RCC1) repeat	Repeat	Interproscan
PF12330 all species →	Haspin_kinase	Haspin like kinase domain	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000719 all species →	Domain	Protein kinase domain	Interproscan
IPR000408 all species →	Repeat	Regulator of chromosome condensation, RCC1	Interproscan
IPR009091 all species →	Homologous_superfamily	Regulator of chromosome condensation 1/beta-lactamase-inhibitor protein II	Interproscan
IPR044120 all species →	Domain	Nek8, catalytic domain	Interproscan
IPR008271 all species →	Active_site	Serine/threonine-protein kinase, active site	Interproscan
IPR051997 all species →	Family	Serine/threonine-protein kinase NEK	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR44535 all species →	PROTEIN CBG16200	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K20877	NEK8; serine/threonine-protein kinase Nek8	EC:2.7.11.1	Cilium and associated proteins	ko03037	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.