Genomic Location: NC_064036.1:17998792...18017194
NR annotation: XP_048581002.1, DNA-binding protein SMUBP-2 isoform X1 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5509393 |
| Transcript |
| rna-XM_048725045.1 |
| Protein |
| XP_048581002.1 |
| UniProt accession | Description |
|---|---|
| P38935 | DNA-binding protein SMUBP-2 OS=Homo sapiens OX=9606 GN=IGHMBP2 PE=1 SV=3 |
| Q9EQN5 | DNA-binding protein SMUBP-2 OS=Rattus norvegicus OX=10116 GN=Ighmbp2 PE=1 SV=1 |
| Q60560 | DNA-binding protein SMUBP-2 OS=Mesocricetus auratus OX=10036 GN=IGHMBP2 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004138 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13087 all species → | AAA_12 | AAA domain | Domain | Interproscan |
| PF01428 all species → | zf-AN1 | AN1-like Zinc finger | Family | Interproscan |
| PF21138 all species → | SMUBP-2_HCS1_1B | Helicase SMUBP-2/HCS1, 1B domain | Domain | Interproscan |
| PF13086 all species → | AAA_11 | AAA domain | Domain | Interproscan |
| PF01424 all species → | R3H | R3H domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036867 all species → | Homologous_superfamily | R3H domain superfamily | Interproscan |
| IPR027417 all species → | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR035896 all species → | Homologous_superfamily | AN1-like Zinc finger | Interproscan |
| IPR004483 all species → | Family | Helicase SMUBP-2/Hcs1-like | Interproscan |
| IPR041679 all species → | Domain | DNA2/NAM7 helicase-like, C-terminal | Interproscan |
| IPR047187 all species → | Domain | Upf1-like, C-terminal helicase domain | Interproscan |
| IPR000058 all species → | Domain | Zinc finger, AN1-type | Interproscan |
| IPR048761 all species → | Domain | Helicase SMUBP-2/HCS1, 1B domain | Interproscan |
| IPR050534 all species → | Family | Coronaviruses polyprotein 1ab | Interproscan |
| IPR041677 all species → | Domain | DNA2/NAM7 helicase, helicase domain | Interproscan |
| IPR001374 all species → | Domain | R3H domain | Interproscan |
| IPR003593 all species → | Domain | AAA+ ATPase domain | Interproscan |
| IPR014001 all species → | Domain | Helicase superfamily 1/2, ATP-binding domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR43788 all species → | DNA2/NAM7 HELICASE FAMILY MEMBER | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003676 all species → | Molecular Function | nucleic acid binding | Interproscan |
| GO:0003677 all species → | Molecular Function | DNA binding | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| GO:0008270 all species → | Molecular Function | zinc ion binding | Interproscan |
| GO:0003723 all species → | Molecular Function | RNA binding | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0043139 all species → | Molecular Function | 5'-3' DNA helicase activity | Interproscan |
| GO:0004386 all species → | Molecular Function | helicase activity | Interproscan |
| GO:0016887 all species → | Molecular Function | ATP hydrolysis activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K19036 | IGHMBP2; ATP-dependent RNA/DNA helicase IGHMBP2 | EC:5.6.2.5 EC:5.6.2.3 | Translation factors | ko03012 | deepkoala |
Transcript abundance of XP_048581002.1 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 1 | 0.81 | 2.43 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 1.92 | 2.53 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 1.56 | 1.84 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 2.26 | 2.84 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 1.63 | 2.15 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 1 | 0.93 | 2.78 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 2 | 1.62 | 2.81 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 2.45 | 2.81 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 2 | 1.54 | 2.50 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 2.38 | 2.81 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 1.46 | 1.87 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 2 | 1.81 | 2.98 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 2 | 1.61 | 2.45 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 1 | 0.88 | 2.65 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 2 | 1.80 | 2.98 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 1 | 0.55 | 1.64 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.