Gene detail

Detailed information of XP_048585744.1 in Nematostella vectensis

Genomic Location: NC_064040.1:5231362...5234088
NR annotation: XP_001624978.3, probable 2-ketogluconate reductase [Nematostella vectensis]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
Q9C4M5	Glyoxylate reductase OS=Thermococcus litoralis (strain ATCC 51850 / DSM 5473 / JCM 8560 / NS-C) OX=523849 GN=gyaR PE=1 SV=1
Q8U3Y2	Glyoxylate reductase OS=Pyrococcus furiosus (strain ATCC 43587 / DSM 3638 / JCM 8422 / Vc1) OX=186497 GN=gyaR PE=1 SV=1
C5A1V0	Glyoxylate reductase OS=Thermococcus gammatolerans (strain DSM 15229 / JCM 11827 / EJ3) OX=593117 GN=gyaR PE=3 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF02826	2-Hacid_dh_C	D-isomer specific 2-hydroxyacid dehydrogenase, NAD binding domain	Domain	Interproscan
PF00389	2-Hacid_dh	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036291	Homologous_superfamily	NAD(P)-binding domain superfamily	Interproscan
IPR029752	Conserved_site	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain conserved site 1	Interproscan
IPR050223	Family	D-isomer specific 2-hydroxyacid dehydrogenase	Interproscan
IPR006140	Domain	D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain	Interproscan
IPR006139	Domain	D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10996	2-HYDROXYACID DEHYDROGENASE-RELATED	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0051287	Molecular Function	NAD binding	Interproscan
GO:0016616	Molecular Function	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K00090	ghrB; glyoxylate/hydroxypyruvate/2-ketogluconate reductase	EC:1.1.1.79 EC:1.1.1.81 EC:1.1.1.215	Glycine, serine and threonine metabolism	ko00260	deepkoala