Genomic Location: NC_064034.1:18855657...18932779
NR annotation: XP_048585850.1, nuclear pore complex protein Nup155 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC116618224 |
| Transcript |
| rna-XM_048729893.1 |
| Protein |
| XP_048585850.1 |
| UniProt accession | Description |
|---|---|
| O75694 | Nuclear pore complex protein Nup155 OS=Homo sapiens OX=9606 GN=NUP155 PE=1 SV=1 |
| Q99P88 | Nuclear pore complex protein Nup155 OS=Mus musculus OX=10090 GN=Nup155 PE=1 SV=1 |
| P37199 | Nuclear pore complex protein Nup155 OS=Rattus norvegicus OX=10116 GN=Nup155 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0004391 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03177 all species → | Nucleoporin_C | Non-repetitive/WGA-negative nucleoporin C-terminal | Family | Interproscan |
| PF08801 all species → | Nucleoporin_N | Nup133 N terminal like | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004870 all species → | Family | Nucleoporin, Nup155-like | Interproscan |
| IPR042537 all species → | Homologous_superfamily | Nucleoporin, Nup155-like, C-terminal, subdomain 2 | Interproscan |
| IPR007187 all species → | Domain | Nucleoporin, Nup133/Nup155-like, C-terminal | Interproscan |
| IPR042533 all species → | Homologous_superfamily | Nucleoporin, Nup155-like, C-terminal, subdomain 1 | Interproscan |
| IPR042538 all species → | Homologous_superfamily | Nucleoporin, Nup155-like, C-terminal, subdomain 3 | Interproscan |
| IPR014908 all species → | Domain | Nucleoporin, Nup133/Nup155-like, N-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10350 all species → | NUCLEAR PORE COMPLEX PROTEIN NUP155 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0000972 all species → | Biological Process | transcription-dependent tethering of RNA polymerase II gene DNA at nuclear periphery | Interproscan |
| GO:0005643 all species → | Cellular Component | nuclear pore | Interproscan |
| GO:0006405 all species → | Biological Process | RNA export from nucleus | Interproscan |
| GO:0006606 all species → | Biological Process | protein import into nucleus | Interproscan |
| GO:0006913 all species → | Biological Process | nucleocytoplasmic transport | Interproscan |
| GO:0017056 all species → | Molecular Function | structural constituent of nuclear pore | Interproscan |
| GO:0036228 all species → | Biological Process | protein localization to nuclear inner membrane | Interproscan |
| GO:0044611 all species → | Cellular Component | nuclear pore inner ring | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K14312 | NUP155, NUP170, NUP157; nuclear pore complex protein Nup155 | - | Messenger RNA biogenesis | ko03019 | deepkoala |
Transcript abundance of XP_048585850.1 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 12.65 | 15.41 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 9.47 | 14.10 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 8.26 | 9.43 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 10.30 | 13.74 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 6.08 | 6.49 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 2 | 9.14 | 13.73 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 2 | 8.09 | 13.72 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 18.93 | 24.39 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 3 | 17.66 | 24.25 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 20.92 | 22.24 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 16.70 | 19.74 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 18.29 | 24.46 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 15.49 | 16.88 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 11.44 | 21.83 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 13.29 | 15.66 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 2 | 9.33 | 14.72 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR6320836 | whole 6 week old aboral regenerate · regenerate 96hpa | whole 6 week old aboral regenerate | six weeks | regenerate 96hpa | SRP125570 | 15.41 |
| SRR6320863 | whole 6 week old aboral regenerate · regenerate 96hpa | whole 6 week old aboral regenerate | six weeks | regenerate 96hpa | SRP125570 | 12.91 |
| SRR6320837 | whole 6 week old aboral regenerate · regenerate 96hpa | whole 6 week old aboral regenerate | six weeks | regenerate 96hpa | SRP125570 | 9.62 |
| SRR6320847 | whole 6 week old aboral regenerate · regenerate 144hpa | whole 6 week old aboral regenerate | six weeks | regenerate 144hpa | SRP125570 | 14.10 |
| SRR6320841 | whole 6 week old aboral regenerate · regenerate 144hpa | whole 6 week old aboral regenerate | six weeks | regenerate 144hpa | SRP125570 | 7.66 |
| SRR6320838 | whole 6 week old aboral regenerate · regenerate 144hpa | whole 6 week old aboral regenerate | six weeks | regenerate 144hpa | SRP125570 | 6.65 |
| SRR6320846 | whole 6 week old aboral regenerate · regenerate 0hpa | whole 6 week old aboral regenerate | six weeks | regenerate 0hpa | SRP125570 | 9.43 |
| SRR6320839 | whole 6 week old aboral regenerate · regenerate 0hpa | whole 6 week old aboral regenerate | six weeks | regenerate 0hpa | SRP125570 | 8.20 |
| SRR6320840 | whole 6 week old aboral regenerate · regenerate 0hpa | whole 6 week old aboral regenerate | six weeks | regenerate 0hpa | SRP125570 | 7.15 |
| SRR6320861 | whole 6 week old aboral regenerate · regenerate 2hpa | whole 6 week old aboral regenerate | six weeks | regenerate 2hpa | SRP125570 | 13.74 |
| SRR6320842 | whole 6 week old aboral regenerate · regenerate 2hpa | whole 6 week old aboral regenerate | six weeks | regenerate 2hpa | SRP125570 | 10.58 |
| SRR6320848 | whole 6 week old aboral regenerate · regenerate 2hpa | whole 6 week old aboral regenerate | six weeks | regenerate 2hpa | SRP125570 | 6.58 |
| SRR6320843 | whole 6 week old aboral regenerate · regenerate uncut | whole 6 week old aboral regenerate | six weeks | regenerate uncut | SRP125570 | 6.49 |
| SRR6320844 | whole 6 week old aboral regenerate · regenerate uncut | whole 6 week old aboral regenerate | six weeks | regenerate uncut | SRP125570 | 6.46 |
| SRR6320845 | whole 6 week old aboral regenerate · regenerate uncut | whole 6 week old aboral regenerate | six weeks | regenerate uncut | SRP125570 | 5.29 |
| SRR6320872 | whole 6 week old aboral regenerate · regenerate 4hpa | whole 6 week old aboral regenerate | six weeks | regenerate 4hpa | SRP125570 | 13.73 |
| SRR6320849 | whole 6 week old aboral regenerate · regenerate 4hpa | whole 6 week old aboral regenerate | six weeks | regenerate 4hpa | SRP125570 | 13.69 |
| SRR6320873 | whole 6 week old aboral regenerate · regenerate 4hpa | whole 6 week old aboral regenerate | six weeks | regenerate 4hpa | SRP125570 | 0.00 |
| SRR6320882 | whole 6 week old aboral regenerate · regenerate 120hpa | whole 6 week old aboral regenerate | six weeks | regenerate 120hpa | SRP125570 | 13.72 |
| SRR6320883 | whole 6 week old aboral regenerate · regenerate 120hpa | whole 6 week old aboral regenerate | six weeks | regenerate 120hpa | SRP125570 | 10.54 |
| SRR6320850 | whole 6 week old aboral regenerate · regenerate 120hpa | whole 6 week old aboral regenerate | six weeks | regenerate 120hpa | SRP125570 | 0.00 |
| SRR6320855 | whole 6 week old aboral regenerate · regenerate 36hpa | whole 6 week old aboral regenerate | six weeks | regenerate 36hpa | SRP125570 | 24.39 |
| SRR6320851 | whole 6 week old aboral regenerate · regenerate 36hpa | whole 6 week old aboral regenerate | six weeks | regenerate 36hpa | SRP125570 | 17.33 |
| SRR6320852 | whole 6 week old aboral regenerate · regenerate 36hpa | whole 6 week old aboral regenerate | six weeks | regenerate 36hpa | SRP125570 | 15.07 |
| SRR6320854 | whole 6 week old aboral regenerate · regenerate 24hpa | whole 6 week old aboral regenerate | six weeks | regenerate 24hpa | SRP125570 | 24.25 |
| SRR6320853 | whole 6 week old aboral regenerate · regenerate 24hpa | whole 6 week old aboral regenerate | six weeks | regenerate 24hpa | SRP125570 | 18.56 |
| SRR6320856 | whole 6 week old aboral regenerate · regenerate 24hpa | whole 6 week old aboral regenerate | six weeks | regenerate 24hpa | SRP125570 | 10.18 |
| SRR6320860 | whole 6 week old aboral regenerate · regenerate 20hpa | whole 6 week old aboral regenerate | six weeks | regenerate 20hpa | SRP125570 | 22.24 |
| SRR6320857 | whole 6 week old aboral regenerate · regenerate 20hpa | whole 6 week old aboral regenerate | six weeks | regenerate 20hpa | SRP125570 | 21.86 |
| SRR6320859 | whole 6 week old aboral regenerate · regenerate 20hpa | whole 6 week old aboral regenerate | six weeks | regenerate 20hpa | SRP125570 | 18.66 |
| SRR6320880 | whole 6 week old aboral regenerate · regenerate 16hpa | whole 6 week old aboral regenerate | six weeks | regenerate 16hpa | SRP125570 | 19.74 |
| SRR6320858 | whole 6 week old aboral regenerate · regenerate 16hpa | whole 6 week old aboral regenerate | six weeks | regenerate 16hpa | SRP125570 | 16.18 |
| SRR6320881 | whole 6 week old aboral regenerate · regenerate 16hpa | whole 6 week old aboral regenerate | six weeks | regenerate 16hpa | SRP125570 | 14.18 |
| SRR6320864 | whole 6 week old aboral regenerate · regenerate 72hpa | whole 6 week old aboral regenerate | six weeks | regenerate 72hpa | SRP125570 | 24.46 |
| SRR6320862 | whole 6 week old aboral regenerate · regenerate 72hpa | whole 6 week old aboral regenerate | six weeks | regenerate 72hpa | SRP125570 | 15.63 |
| SRR6320865 | whole 6 week old aboral regenerate · regenerate 72hpa | whole 6 week old aboral regenerate | six weeks | regenerate 72hpa | SRP125570 | 14.76 |
| SRR6320869 | whole 6 week old aboral regenerate · regenerate 60hpa | whole 6 week old aboral regenerate | six weeks | regenerate 60hpa | SRP125570 | 16.88 |
| SRR6320866 | whole 6 week old aboral regenerate · regenerate 60hpa | whole 6 week old aboral regenerate | six weeks | regenerate 60hpa | SRP125570 | 15.72 |
| SRR6320867 | whole 6 week old aboral regenerate · regenerate 60hpa | whole 6 week old aboral regenerate | six weeks | regenerate 60hpa | SRP125570 | 13.87 |
| SRR6320870 | whole 6 week old aboral regenerate · regenerate 48hpa | whole 6 week old aboral regenerate | six weeks | regenerate 48hpa | SRP125570 | 21.83 |
| SRR6320871 | whole 6 week old aboral regenerate · regenerate 48hpa | whole 6 week old aboral regenerate | six weeks | regenerate 48hpa | SRP125570 | 12.49 |
| SRR6320868 | whole 6 week old aboral regenerate · regenerate 48hpa | whole 6 week old aboral regenerate | six weeks | regenerate 48hpa | SRP125570 | 0.00 |
| SRR6320875 | whole 6 week old aboral regenerate · regenerate 8hpa | whole 6 week old aboral regenerate | six weeks | regenerate 8hpa | SRP125570 | 15.66 |
| SRR6320874 | whole 6 week old aboral regenerate · regenerate 8hpa | whole 6 week old aboral regenerate | six weeks | regenerate 8hpa | SRP125570 | 13.45 |
| SRR6320876 | whole 6 week old aboral regenerate · regenerate 8hpa | whole 6 week old aboral regenerate | six weeks | regenerate 8hpa | SRP125570 | 10.77 |
| SRR6320877 | whole 6 week old aboral regenerate · regenerate 12hpa | whole 6 week old aboral regenerate | six weeks | regenerate 12hpa | SRP125570 | 14.72 |
| SRR6320879 | whole 6 week old aboral regenerate · regenerate 12hpa | whole 6 week old aboral regenerate | six weeks | regenerate 12hpa | SRP125570 | 13.26 |
| SRR6320878 | whole 6 week old aboral regenerate · regenerate 12hpa | whole 6 week old aboral regenerate | six weeks | regenerate 12hpa | SRP125570 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Nematostella vectensis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 31 | XP_048585615.1 | 0.886550387805637 |
| Negatively correlated | 5 | XP_032231043.1 | -0.726759127832258 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Nematostella vectensis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
| Dataset | Tissue / stage | Cells | Cell types | This gene | Marker of |
|---|---|---|---|---|---|
| NVECT_2month | 2 month animal · Adult tissues/organs | 1,614 | 23 | not in this dataset | – |
| NVECT_bodywall | body wall with mesenteries · 6-8 weeks adults | 11,742 | 13 | not in this dataset | – |
| NVECT_embryo | embryos · 8, 10 and 12 h after fertilisation (deposit labels 8h/10h/12h) | 9,711 | 17 | not in this dataset | – |
| NVECT_gastrula | Blastula-gastrula intermediate · Developmental stages | 49,166 | 27 | not in this dataset | – |
| NVECT_gastruloid | dissociated and reaggregated embryos · 4-48 hpa | 36,550 | 8 | not in this dataset | – |
| NVECT_neoplasm | neoplasm · Adult tissues/organs | 2,532 | 16 | not in this dataset | – |
| NVECT_nervous | Gastrula Cells · nervous system | 16,590 | 27 | unmapped | – |
| NVECT_notch48h | embryos treated 24-48 hpf (DMSO vs LY411575) · 48 hpf | 19,044 | 7 | not in this dataset | – |
| NVECT_tentacle | tentacle · Adult tissues/organs | 7,977 | 19 | not in this dataset | – |
A gene is in viewer when the dataset ships a per-cell expression vector for it; marker only means it is in the dataset’s ranked marker table but no vector was exported, so the atlas cannot draw it; not in this dataset means the dataset’s own gene-ID table does not list it, so no expression claim can be made for that dataset. unmapped is deliberately weaker still: the dataset has no gene-ID table on CnidoSite yet, so nothing is claimed in either direction. Where markers are listed, the numbers are log2 fold change and the percentage of cells of that type in which the gene was detected.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
| Assay | Sample | Peaks | Region |
|---|---|---|---|
| ChIP-seq | H3K27ac_gastrulae_24h | 1 | Promoter (<=1kb) 1 |
| H3K27ac_planulae_4days | 1 | Promoter (<=1kb) 1 | |
| H3K4me2_gastrulae_24h | 1 | Promoter (<=1kb) 1 | |
| H3K4me2_planulae_4days | 1 | Promoter (<=1kb) 1 | |
| H3K4me2_polyps | 1 | Promoter (<=1kb) 1 | |
| H3K4me3_gastrulae_24h | 1 | Promoter (<=1kb) 1 | |
| H3K4me3_planulae_4days | 1 | Promoter (<=1kb) 1 | |
| H3K4me3_polyps | 1 | Promoter (<=1kb) 1 | |
| H3K27ac_Ncol3_negative | 1 | Promoter (<=1kb) 1 | |
| H3K27ac_Ncol3_positive | 1 | Promoter (<=1kb) 1 | |
| H3K27ac_Nep3_negative | 1 | Promoter (<=1kb) 1 | |
| H3K27ac_Nep3_positive | 1 | Promoter (<=1kb) 1 | |
| H3K36me3_gastrulae_24h | 2 | Promoter (<=1kb) 1 · Promoter (2-3kb) 1 | |
| H3K36me3_planulae_4days | 1 | Promoter (<=1kb) 1 | |
| H3K36me3_polyps | 1 | Promoter (<=1kb) 1 |
4 further sample(s) also have peaks at this gene; open the assay page below to see them all.
Browse the full epigenomic landscape of this species: ChIP-seq · ATAC-seq.
| Sample | Methylation profile |
|---|---|
| Whole_adults | open |
The DNA Methylation page locates this gene by scanning the bisulphite table, which holds one row per cytosine. For the largest datasets that scan takes a while to return; it does not mean the link is broken.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
