Genomic Location: NC_064040.1:6000537...6010341
NR annotation: XP_048586480.1, NAD-dependent protein deacetylase sirtuin-2 isoform X2 [Nematostella vectensis]
| CDS | |||||
| LOC5520709 | |||||
| Transcript |
| rna-XM_048730523.1 |
| Protein |
| XP_048586480.1 |
| Uniprot term | Description |
|---|---|
| Q7ZVK3 | NAD-dependent protein deacetylase sirtuin-2 OS=Danio rerio OX=7955 GN=sirt2 PE=1 SV=1 |
| Q8VDQ8 | NAD-dependent protein deacetylase sirtuin-2 OS=Mus musculus OX=10090 GN=Sirt2 PE=1 SV=2 |
| Q5RJQ4 | NAD-dependent protein deacetylase sirtuin-2 OS=Rattus norvegicus OX=10116 GN=Sirt2 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF02146 | SIR2 | Sir2 family | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR017328 | Family | Sirtuin, class I | Interproscan |
| IPR050134 | Family | NAD-dependent sirtuin protein deacylases | Interproscan |
| IPR026591 | Homologous_superfamily | Sirtuin, catalytic core small domain superfamily | Interproscan |
| IPR026590 | Domain | Sirtuin family, catalytic core domain | Interproscan |
| IPR029035 | Homologous_superfamily | DHS-like NAD/FAD-binding domain superfamily | Interproscan |
| IPR003000 | Family | Sirtuin family | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11085 | NAD-DEPENDENT PROTEIN DEACYLASE SIRTUIN-5, MITOCHONDRIAL-RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0017136 | Molecular Function | histone deacetylase activity, NAD-dependent | Interproscan |
| GO:0051287 | Molecular Function | NAD binding | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0070403 | Molecular Function | NAD+ binding | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11412 | SIRT2, SIR2L2; NAD-dependent protein deacetylase sirtuin 2 | EC:2.3.1.286 | Chromosome and associated proteins | ko03036 | deepkoala |