Genomic Location: NC_064041.1:4779334...4788765
NR annotation: XP_048587301.1, disintegrin and metalloproteinase domain-containing protein 10 [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5501630 |
| Transcript |
| rna-XM_048731344.1 |
| Protein |
| XP_048587301.1 |
| UniProt accession | Description |
|---|---|
| O77633 | Disintegrin and metalloproteinase domain-containing protein 10 OS=Sus scrofa OX=9823 GN=ADAM10 PE=2 SV=2 |
| Q10741 | Disintegrin and metalloproteinase domain-containing protein 10 OS=Bos taurus OX=9913 GN=ADAM10 PE=1 SV=1 |
| O35598 | Disintegrin and metalloproteinase domain-containing protein 10 OS=Mus musculus OX=10090 GN=Adam10 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000651 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13688 all species → | Reprolysin_5 | Metallo-peptidase family M12 | Family | Interproscan |
| PF21299 all species → | ADAM10_Cys-rich | ADAM10, cysteine-rich domain | Domain | Interproscan |
| PF00200 all species → | Disintegrin | Disintegrin | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036436 all species → | Homologous_superfamily | Disintegrin domain superfamily | Interproscan |
| IPR051489 all species → | Family | Disintegrin and Metalloproteinase Domain-Containing | Interproscan |
| IPR024079 all species → | Homologous_superfamily | Metallopeptidase, catalytic domain superfamily | Interproscan |
| IPR049038 all species → | Domain | ADAM10, cysteine-rich domain | Interproscan |
| IPR001762 all species → | Domain | Disintegrin domain | Interproscan |
| IPR001590 all species → | Domain | Peptidase M12B, ADAM/reprolysin | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45702 all species → | ADAM10/ADAM17 METALLOPEPTIDASE FAMILY MEMBER | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004222 all species → | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0006509 all species → | Biological Process | membrane protein ectodomain proteolysis | Interproscan |
| GO:0007219 all species → | Biological Process | Notch signaling pathway | Interproscan |
| GO:0008237 all species → | Molecular Function | metallopeptidase activity | Interproscan |
| GO:0006508 all species → | Biological Process | proteolysis | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06704 | ADAM10, CD156c; disintegrin and metalloproteinase domain-containing protein 10 | EC:3.4.24.81 | CD molecules | ko04090 | deepkoala |
Transcript abundance of XP_048587301.1 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 66.09 | 76.45 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 53.68 | 68.37 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 61.06 | 68.19 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 77.77 | 86.69 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 59.24 | 73.40 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 3 | 82.40 | 95.18 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 68.95 | 72.54 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 61.44 | 65.49 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 3 | 59.24 | 66.53 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 64.13 | 66.02 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 67.76 | 73.06 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 79.63 | 104.72 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 69.46 | 81.97 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 47.91 | 72.96 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 69.18 | 79.50 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 3 | 73.21 | 87.16 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
