Genomic Location: NC_064041.1:15092718...15111849
NR annotation: XP_048587374.1, pappalysin-1 [Nematostella vectensis]
| CDS | |||||
| LOC5506035 | |||||
| Transcript |
| rna-XM_048731430.1 |
| Protein |
| XP_048587387.1 |
| Uniprot term | Description |
|---|---|
| Q13219 | Pappalysin-1 OS=Homo sapiens OX=9606 GN=PAPPA PE=1 SV=3 |
| Q8R4K8 | Pappalysin-1 OS=Mus musculus OX=10090 GN=Pappa PE=2 SV=2 |
| Q9BXP8 | Pappalysin-2 OS=Homo sapiens OX=9606 GN=PAPPA2 PE=1 SV=4 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00084 | Sushi | Sushi repeat (SCR repeat) | Domain | Interproscan |
| PF13385 | Laminin_G_3 | Concanavalin A-like lectin/glucanases superfamily | Domain | Interproscan |
| PF05572 | Peptidase_M43 | Pregnancy-associated plasma protein-A | Family | Interproscan |
| PF00066 | Notch | LNR domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR043543 | Family | Pappalysin-1/2 | Interproscan |
| IPR000800 | Domain | Notch domain | Interproscan |
| IPR035976 | Homologous_superfamily | Sushi/SCR/CCP superfamily | Interproscan |
| IPR000436 | Domain | Sushi/SCR/CCP domain | Interproscan |
| IPR011936 | Repeat | Myxococcus cysteine-rich repeat | Interproscan |
| IPR003961 | Domain | Fibronectin type III | Interproscan |
| IPR006558 | Domain | LamG-like jellyroll fold | Interproscan |
| IPR036116 | Homologous_superfamily | Fibronectin type III superfamily | Interproscan |
| IPR008754 | Domain | Peptidase M43, pregnancy-associated plasma-A | Interproscan |
| IPR013320 | Homologous_superfamily | Concanavalin A-like lectin/glucanase domain superfamily | Interproscan |
| IPR024079 | Homologous_superfamily | Metallopeptidase, catalytic domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46130 | LAMGL DOMAIN-CONTAINING PROTEIN | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0004222 | Molecular Function | metalloendopeptidase activity | Interproscan |
| GO:0005615 | Cellular Component | extracellular space | Interproscan |
| GO:0006508 | Biological Process | proteolysis | Interproscan |
| GO:0007166 | Biological Process | cell surface receptor signaling pathway | Interproscan |
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0008237 | Molecular Function | metallopeptidase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K07762 | PAPPA; pappalysin-1 | EC:3.4.24.79 | Peptidases and inhibitors | ko01002 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
© 2026 All Rights Reserved.
