Genomic Location: NC_064043.1:14664206...14679143
NR annotation: XP_048589167.1, NAD(P) transhydrogenase, mitochondrial [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5500559 |
| Transcript |
| rna-XM_048733210.1 |
| Protein |
| XP_048589167.1 |
| UniProt accession | Description |
|---|---|
| W5PFI3 | NAD(P) transhydrogenase, mitochondrial OS=Ovis aries OX=9940 GN=NNT PE=1 SV=2 |
| Q13423 | NAD(P) transhydrogenase, mitochondrial OS=Homo sapiens OX=9606 GN=NNT PE=1 SV=3 |
| P11024 | NAD(P) transhydrogenase, mitochondrial OS=Bos taurus OX=9913 GN=NNT PE=1 SV=3 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003192 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF12769 all species → | PNTB_4TM | 4TM region of pyridine nucleotide transhydrogenase, mitoch | Family | Interproscan |
| PF05222 all species → | AlaDh_PNT_N | Alanine dehydrogenase/PNT, N-terminal domain | Domain | Interproscan |
| PF01262 all species → | AlaDh_PNT_C | Alanine dehydrogenase/PNT, C-terminal domain | Domain | Interproscan |
| PF02233 all species → | PNTB | NAD(P) transhydrogenase beta subunit | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR026255 all species → | Family | NAD(P) transhydrogenase, alpha subunit | Interproscan |
| IPR024605 all species → | Domain | NAD(P) transhydrogenase, alpha subunit, C-terminal | Interproscan |
| IPR007886 all species → | Domain | Alanine dehydrogenase/pyridine nucleotide transhydrogenase, N-terminal | Interproscan |
| IPR007698 all species → | Domain | Alanine dehydrogenase/pyridine nucleotide transhydrogenase, NAD(H)-binding domain | Interproscan |
| IPR029035 all species → | Homologous_superfamily | DHS-like NAD/FAD-binding domain superfamily | Interproscan |
| IPR036291 all species → | Homologous_superfamily | NAD(P)-binding domain superfamily | Interproscan |
| IPR034300 all species → | Domain | NADP transhydrogenase beta-like domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10160 all species → | NAD(P) TRANSHYDROGENASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0008746 all species → | Molecular Function | obsolete NAD(P)+ transhydrogenase activity | Interproscan |
| GO:1902600 all species → | Biological Process | proton transmembrane transport | Interproscan |
| GO:0005743 all species → | Cellular Component | mitochondrial inner membrane | Interproscan |
| GO:0006740 all species → | Biological Process | NADPH regeneration | Interproscan |
| GO:0050661 all species → | Molecular Function | NADP binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K00323 | NNT; proton-translocating NAD(P)+ transhydrogenase | EC:7.1.1.1 | Nicotinate and nicotinamide metabolism | ko00760 | deepkoala |
Transcript abundance of XP_048589167.1 across 48 RNA-seq samples of Nematostella vectensis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 3 | 65.76 | 70.15 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 3 | 47.01 | 60.75 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 3 | 42.22 | 44.47 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 3 | 47.68 | 53.38 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 3 | 38.27 | 40.08 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 3 | 57.32 | 66.07 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 3 | 65.91 | 78.44 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 3 | 72.92 | 85.56 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 3 | 63.88 | 68.63 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 3 | 60.24 | 61.68 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 3 | 55.94 | 63.85 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 3 | 67.17 | 70.71 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 3 | 63.12 | 71.36 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 2 | 50.13 | 78.96 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 3 | 64.25 | 65.99 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 3 | 64.00 | 64.59 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.