Genomic Location: NC_064044.1:7859402...7874820
NR annotation: XP_048590140.1, glutamate--cysteine ligase catalytic subunit [Nematostella vectensis]
Species Nematostella vectensis · all data for this species · gene families
| CDS |
| LOC5518386 |
| Transcript |
| rna-XM_048734184.1 |
| Protein |
| XP_048590141.1 |
| UniProt accession | Description |
|---|---|
| P97494 | Glutamate--cysteine ligase catalytic subunit OS=Mus musculus OX=10090 GN=Gclc PE=1 SV=4 |
| P19468 | Glutamate--cysteine ligase catalytic subunit OS=Rattus norvegicus OX=10116 GN=Gclc PE=1 SV=2 |
| P48506 | Glutamate--cysteine ligase catalytic subunit OS=Homo sapiens OX=9606 GN=GCLC PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001812 (this species only) |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF03074 all species → | GCS | Glutamate-cysteine ligase | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR004308 all species → | Family | Glutamate-cysteine ligase catalytic subunit | Interproscan |
| IPR014746 all species → | Homologous_superfamily | Glutamine synthetase/guanido kinase, catalytic domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11164 all species → | GLUTAMATE CYSTEINE LIGASE | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004357 all species → | Molecular Function | glutamate-cysteine ligase activity | Interproscan |
| GO:0006750 all species → | Biological Process | glutathione biosynthetic process | Interproscan |
| GO:0003824 all species → | Molecular Function | catalytic activity | Interproscan |
| GO:0017109 all species → | Cellular Component | glutamate-cysteine ligase complex | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11204 | GCLC; glutamate--cysteine ligase catalytic subunit | EC:6.3.2.2 | Longevity regulating pathway - worm | ko04212 | deepkoala |
Transcript abundance of XP_048590141.1 across 48 RNA-seq samples of Nematostella vectensis. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| whole 6 week old aboral regenerate · regenerate 96hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 144hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 0hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 2hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate uncut | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 4hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 120hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 36hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 24hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 20hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 16hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 72hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 60hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 48hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 8hpa | 3 | 0 | 0.00 | 0.00 | |
| whole 6 week old aboral regenerate · regenerate 12hpa | 3 | 0 | 0.00 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (NVECT_TPM,
StringTie quantification over 48 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
