Genomic Location: NC_088920.1:62619884...62662962
NR annotation: XP_047129983.1, lysine-specific demethylase 6A isoform X2 [Hydra vulgaris]
| CDS | |||||
| LOC100197335 | |||||
| Transcript |
| rna-XM_065788881.1 |
| Protein |
| XP_065644953.1 |
| Uniprot term | Description |
|---|---|
| P79457 | Histone demethylase UTY OS=Mus musculus OX=10090 GN=Uty PE=1 SV=2 |
| O70546 | Lysine-specific demethylase 6A OS=Mus musculus OX=10090 GN=Kdm6a PE=1 SV=2 |
| O15550 | Lysine-specific demethylase 6A OS=Homo sapiens OX=9606 GN=KDM6A PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21326 | KDM6_GATAL | KDM6, GATA-like | Domain | Interproscan |
| PF21322 | KDM6_C-hel | Lysine-specific demethylase 6/UTY, C-terminal helical domain | Domain | Interproscan |
| PF13432 | TPR_16 | Tetratricopeptide repeat | Repeat | Interproscan |
| PF02373 | JmjC | JmjC domain, hydroxylase | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011990 | Homologous_superfamily | Tetratricopeptide-like helical domain superfamily | Interproscan |
| IPR003347 | Domain | JmjC domain | Interproscan |
| IPR046941 | Homologous_superfamily | Lysine-specific demethylase 6, GATA-like domain superfamily | Interproscan |
| IPR019734 | Repeat | Tetratricopeptide repeat | Interproscan |
| IPR048560 | Domain | Lysine-specific demethylase 6A/B-like, GATA-like | Interproscan |
| IPR051630 | Family | Transcriptional Corepressor and Histone Demethylase | Interproscan |
| IPR048562 | Domain | Lysine-specific demethylase 6A/B-like, C-terminal helical domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR14017 | LYSINE-SPECIFIC DEMETHYLASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0000978 | Molecular Function | RNA polymerase II cis-regulatory region sequence-specific DNA binding | Interproscan |
| GO:0010468 | Biological Process | regulation of gene expression | Interproscan |
| GO:0031490 | Molecular Function | chromatin DNA binding | Interproscan |
| GO:0044666 | Cellular Component | MLL3/4 complex | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K11447 | UTX, KDM6A; lysine-specific demethylase 6A | EC:1.14.11.68 | Chromosome and associated proteins | ko03036 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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