Genomic Location: NC_088924.1:14236596...14327149
NR annotation: XP_047124993.1, leucine-rich repeat serine/threonine-protein kinase 2 isoform X1 [Hydra vulgaris]
| CDS | |||||
| LOC136080602 | |||||
| Transcript |
| rna-XM_065797456.1 |
| Protein |
| XP_065653528.1 |
| Uniprot term | Description |
|---|---|
| Q5S006 | Leucine-rich repeat serine/threonine-protein kinase 2 OS=Mus musculus OX=10090 GN=Lrrk2 PE=1 SV=2 |
| Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 OS=Homo sapiens OX=9606 GN=LRRK2 PE=1 SV=2 |
| Q38SD2 | Leucine-rich repeat serine/threonine-protein kinase 1 OS=Homo sapiens OX=9606 GN=LRRK1 PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08477 | Roc | Ras of Complex, Roc, domain of DAPkinase | Domain | Interproscan |
| PF13855 | LRR_8 | Leucine rich repeat | Repeat | Interproscan |
| PF16095 | COR | C-terminal of Roc, COR, domain | Family | Interproscan |
| PF12796 | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR011989 | Homologous_superfamily | Armadillo-like helical | Interproscan |
| IPR001611 | Repeat | Leucine-rich repeat | Interproscan |
| IPR032675 | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR036770 | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR032171 | Domain | C-terminal of Roc (COR) domain | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR016024 | Homologous_superfamily | Armadillo-type fold | Interproscan |
| IPR036322 | Homologous_superfamily | WD40-repeat-containing domain superfamily | Interproscan |
| IPR020859 | Domain | Roc domain | Interproscan |
| IPR002110 | Repeat | Ankyrin repeat | Interproscan |
| IPR050715 | Family | Leucine-rich repeat and signaling effector domain-containing protein | Interproscan |
| IPR003591 | Repeat | Leucine-rich repeat, typical subtype | Interproscan |
| IPR015943 | Homologous_superfamily | WD40/YVTN repeat-like-containing domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45752 | LEUCINE-RICH REPEAT-CONTAINING | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K08844 | LRRK2; leucine-rich repeat kinase 2 | EC:2.7.11.1 | Exosome | ko04147 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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