Genomic Location: NC_088925.1:7890510...7966498
NR annotation: XP_047139260.1, eIF-2-alpha kinase GCN2 isoform X1 [Hydra vulgaris]
| CDS | |||||
| LOC136081622 | |||||
| Transcript |
| rna-XM_065799124.1 |
| Protein |
| XP_065655196.1 |
| Uniprot term | Description |
|---|---|
| D4A7V9 | eIF-2-alpha kinase GCN2 OS=Rattus norvegicus OX=10116 GN=Eif2ak4 PE=3 SV=2 |
| Q9P2K8 | eIF-2-alpha kinase GCN2 OS=Homo sapiens OX=9606 GN=EIF2AK4 PE=1 SV=3 |
| Q9QZ05 | eIF-2-alpha kinase GCN2 OS=Mus musculus OX=10090 GN=Eif2ak4 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13393 | tRNA-synt_His | Histidyl-tRNA synthetase | Domain | Interproscan |
| PF05773 | RWD | RWD domain | Domain | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR006575 | Domain | RWD domain | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR041715 | Domain | Class II Histidinyl-tRNA synthetase (HisRS)-like catalytic core domain | Interproscan |
| IPR016135 | Homologous_superfamily | Ubiquitin-conjugating enzyme/RWD-like | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR050339 | Family | Cell Cycle and Stress Response Kinase | Interproscan |
| IPR045864 | Homologous_superfamily | Class II Aminoacyl-tRNA synthetase/Biotinyl protein ligase (BPL) and lipoyl protein ligase (LPL) | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR11042 | EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0005634 | Cellular Component | nucleus | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K16196 | EIF2AK4; eukaryotic translation initiation factor 2-alpha kinase 4 | EC:2.7.11.1 | Protein kinases | ko01001 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
© 2026 All Rights Reserved.
