Genomic Location: NC_088926.1:10486236...10611145
NR annotation: XP_047123611.1, phosphatidylinositol 3-kinase regulatory subunit alpha [Hydra vulgaris]
| CDS | |||||
| LOC100210096 | |||||
| Transcript |
| rna-XM_065801009.1 |
| Protein |
| XP_065657081.1 |
| Uniprot term | Description |
|---|---|
| Q45FX5 | Protein vav-1 OS=Caenorhabditis elegans OX=6239 GN=vav-1 PE=1 SV=1 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF07647 | SAM_2 | SAM domain (Sterile alpha motif) | Domain | Interproscan |
| PF00017 | SH2 | SH2 domain | Domain | Interproscan |
| PF00620 | RhoGAP | RhoGAP domain | Domain | Interproscan |
| PF00130 | C1_1 | Phorbol esters/diacylglycerol binding domain (C1 domain) | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002219 | Domain | Protein kinase C-like, phorbol ester/diacylglycerol-binding domain | Interproscan |
| IPR001660 | Domain | Sterile alpha motif domain | Interproscan |
| IPR008936 | Homologous_superfamily | Rho GTPase activation protein | Interproscan |
| IPR000198 | Domain | Rho GTPase-activating protein domain | Interproscan |
| IPR046349 | Homologous_superfamily | C1-like domain superfamily | Interproscan |
| IPR036860 | Homologous_superfamily | SH2 domain superfamily | Interproscan |
| IPR000980 | Domain | SH2 domain | Interproscan |
| IPR001452 | Domain | SH3 domain | Interproscan |
| IPR013761 | Homologous_superfamily | Sterile alpha motif/pointed domain superfamily | Interproscan |
| IPR036028 | Homologous_superfamily | SH3-like domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45818 | PROTEIN VAV | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0007165 | Biological Process | signal transduction | Interproscan |
| GO:0005085 | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0016477 | Biological Process | cell migration | Interproscan |
| GO:0043087 | Biological Process | regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K02649 | PIK3R1_2_3; phosphoinositide-3-kinase regulatory subunit alpha/beta/delta | - | Membrane trafficking | ko04131 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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