Genomic Location: NC_088927.1:13483215...13589774
NR annotation: XP_047143282.1, leucine-rich repeat serine/threonine-protein kinase 2-like isoform X2 [Hydra vulgaris]
| CDS | ||||
| LOC136083640 | ||||
| Transcript |
| rna-XM_065803118.1 |
| Protein |
| XP_065659190.1 |
| Uniprot term | Description |
|---|---|
| Q5S006 | Leucine-rich repeat serine/threonine-protein kinase 2 OS=Mus musculus OX=10090 GN=Lrrk2 PE=1 SV=2 |
| Q55E58 | Probable serine/threonine-protein kinase pats1 OS=Dictyostelium discoideum OX=44689 GN=pats1 PE=3 SV=1 |
| Q5S007 | Leucine-rich repeat serine/threonine-protein kinase 2 OS=Homo sapiens OX=9606 GN=LRRK2 PE=1 SV=2 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF13855 | LRR_8 | Leucine rich repeat | Repeat | Interproscan |
| PF12796 | Ank_2 | Ankyrin repeats (3 copies) | Repeat | Interproscan |
| PF16095 | COR | C-terminal of Roc, COR, domain | Family | Interproscan |
| PF08477 | Roc | Ras of Complex, Roc, domain of DAPkinase | Domain | Interproscan |
| PF00069 | Pkinase | Protein kinase domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036770 | Homologous_superfamily | Ankyrin repeat-containing domain superfamily | Interproscan |
| IPR002110 | Repeat | Ankyrin repeat | Interproscan |
| IPR003591 | Repeat | Leucine-rich repeat, typical subtype | Interproscan |
| IPR032675 | Homologous_superfamily | Leucine-rich repeat domain superfamily | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR001611 | Repeat | Leucine-rich repeat | Interproscan |
| IPR008271 | Active_site | Serine/threonine-protein kinase, active site | Interproscan |
| IPR011009 | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR011044 | Homologous_superfamily | Quinoprotein amine dehydrogenase, beta chain-like | Interproscan |
| IPR020859 | Domain | Roc domain | Interproscan |
| IPR032171 | Domain | C-terminal of Roc (COR) domain | Interproscan |
| IPR000719 | Domain | Protein kinase domain | Interproscan |
| IPR005225 | Domain | Small GTP-binding protein domain | Interproscan |
| IPR017441 | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR053215 | Family | TKL Ser/Thr protein kinase | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45756 | PALMITOYLTRANSFERASE | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005515 | Molecular Function | protein binding | Interproscan |
| GO:0004672 | Molecular Function | protein kinase activity | Interproscan |
| GO:0006468 | Biological Process | protein phosphorylation | Interproscan |
| GO:0005524 | Molecular Function | ATP binding | Interproscan |
| GO:0005525 | Molecular Function | GTP binding | Interproscan |