Gene detail

Detailed information of XP_066915498.1 in Clytia hemisphaerica

Genomic Location: NW_027103633.1:702484...703379
NR annotation: XP_002157214.1, dihydrofolate reductase [Hydra vulgaris]

Gene Structure

Sequence

Uniprot

Uniprot term	Description
P09503	Viral dihydrofolate reductase OS=Saimiriine herpesvirus 2 (strain 11) OX=10383 GN=DHFR PE=3 SV=1
P00374	Dihydrofolate reductase OS=Homo sapiens OX=9606 GN=DHFR PE=1 SV=2
P00377	Dihydrofolate reductase OS=Sus scrofa OX=9823 GN=DHFR PE=1 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00186	DHFR_1	Dihydrofolate reductase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR001796	Domain	Dihydrofolate reductase domain	Interproscan
IPR017925	Conserved_site	Dihydrofolate reductase conserved site	Interproscan
IPR024072	Homologous_superfamily	Dihydrofolate reductase-like domain superfamily	Interproscan
IPR012259	Family	Dihydrofolate reductase	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR48069	DIHYDROFOLATE REDUCTASE	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0004146	Molecular Function	dihydrofolate reductase activity	Interproscan
GO:0046654	Biological Process	tetrahydrofolate biosynthetic process	Interproscan
GO:0005739	Cellular Component	mitochondrion	Interproscan
GO:0046452	Biological Process	dihydrofolate metabolic process	Interproscan
GO:0046655	Biological Process	folic acid metabolic process	Interproscan
GO:0050661	Molecular Function	NADP binding	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K00287	DHFR, folA; dihydrofolate reductase	EC:1.5.1.3	Antifolate resistance	ko01523	deepkoala