Genomic Location: NW_027103768.1:418258...440998
NR annotation: XP_047126178.1, DNA replication ATP-dependent helicase/nuclease DNA2 [Hydra vulgaris]
| CDS | |||||
| XP_066918351.1 | |||||
| Transcript |
| - |
| Protein |
| XP_066918351.1 |
| Uniprot term | Description |
|---|---|
| Q8QHA5 | DNA replication ATP-dependent helicase/nuclease DNA2 OS=Xenopus laevis OX=8355 GN=dna2 PE=1 SV=1 |
| E1BMP7 | DNA replication ATP-dependent helicase/nuclease DNA2 OS=Bos taurus OX=9913 GN=DNA2 PE=3 SV=3 |
| P51530 | DNA replication ATP-dependent helicase/nuclease DNA2 OS=Homo sapiens OX=9606 GN=DNA2 PE=1 SV=3 |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21123 | Dna2_Rift | Dna2 Rift barrel domain | Domain | Interproscan |
| PF13086 | AAA_11 | AAA domain | Domain | Interproscan |
| PF13087 | AAA_12 | AAA domain | Domain | Interproscan |
| PF08696 | Dna2 | DNA replication factor Dna2 | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR047187 | Domain | Upf1-like, C-terminal helicase domain | Interproscan |
| IPR045055 | Family | DNA2/NAM7-like helicase | Interproscan |
| IPR027417 | Homologous_superfamily | P-loop containing nucleoside triphosphate hydrolase | Interproscan |
| IPR048459 | Domain | DNA2, rift barrel domain | Interproscan |
| IPR026851 | Domain | DNA replication ATP-dependent helicase/nuclease Dna2/JHS1, DEXXQ-box helicase domain | Interproscan |
| IPR041677 | Domain | DNA2/NAM7 helicase, helicase domain | Interproscan |
| IPR041679 | Domain | DNA2/NAM7 helicase-like, C-terminal | Interproscan |
| IPR011604 | Homologous_superfamily | PD-(D/E)XK endonuclease-like domain superfamily | Interproscan |
| IPR014808 | Domain | DNA replication factor Dna2, N-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10887 | DNA2/NAM7 HELICASE FAMILY | Interproscan |
| GO terms | Category | Description | Source |
|---|---|---|---|
| GO:0005737 | Cellular Component | cytoplasm | Interproscan |
| GO:0017108 | Molecular Function | 5'-flap endonuclease activity | Interproscan |
| GO:0071932 | Biological Process | replication fork reversal | Interproscan |
| GO:0017116 | Molecular Function | single-stranded DNA helicase activity | Interproscan |
| GO:0004386 | Molecular Function | helicase activity | Interproscan |
| KO | Enzyme | Enzyme ID | pathway | mapID | Source |
|---|---|---|---|---|---|
| K10742 | DNA2; DNA replication ATP-dependent helicase/nuclease Dna2 | EC:5.6.2.3 EC:3.1.-.- | DNA replication proteins | ko03032 | deepkoala |
Maintained by Dr. Jiajie She from Prof. Longjun Wu's Lab & Prof. Pei-yuan Qian's Lab
Hong Kong Branch of the Southern Marine Science and Engineering Guangdong Laboratory (Guangzhou)
Hong Kong University of Science and Technology
Clear Water Bay, Kowloon, Hong Kong
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