Detailed information of XP_066920621.1 in Clytia hemisphaerica

Genomic Location: NW_027103852.1:247656...279690
NR annotation: XP_047133065.1, cysteine desulfurase, mitochondrial [Hydra vulgaris]
Species Clytia hemisphaerica · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9Y697Cysteine desulfurase OS=Homo sapiens OX=9606 GN=NFS1 PE=1 SV=3
Q5RDE7Cysteine desulfurase OS=Pongo abelii OX=9601 GN=NFS1 PE=2 SV=1
Q9Z1J3Cysteine desulfurase OS=Mus musculus OX=10090 GN=Nfs1 PE=1 SV=3
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001536 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00266
all species →		Aminotran_5Aminotransferase class-VDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR015422
all species →		Homologous_superfamilyPyridoxal phosphate-dependent transferase, small domainInterproscan
IPR015421
all species →		Homologous_superfamilyPyridoxal phosphate-dependent transferase, major domainInterproscan
IPR010240
all species →		FamilyCysteine desulfurase IscSInterproscan
IPR020578
all species →		Binding_siteAminotransferase class-V, pyridoxal-phosphate binding siteInterproscan
IPR016454
all species →		FamilyCysteine desulfuraseInterproscan
IPR000192
all species →		DomainAminotransferase class V domainInterproscan
IPR015424
all species →		Homologous_superfamilyPyridoxal phosphate-dependent transferaseInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR11601
all species →		CYSTEINE DESULFURYLASE FAMILY MEMBERInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0030170
all species →		Molecular Functionpyridoxal phosphate bindingInterproscan
GO:0031071
all species →		Molecular Functioncysteine desulfurase activityInterproscan
GO:0044571
all species →		Biological Process[2Fe-2S] cluster assemblyInterproscan
GO:0005634
all species →		Cellular ComponentnucleusInterproscan
GO:0005739
all species →		Cellular ComponentmitochondrionInterproscan
GO:0005829
all species →		Cellular ComponentcytosolInterproscan
GO:0016226
all species →		Biological Processiron-sulfur cluster assemblyInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K04487iscS, NFS1; cysteine desulfuraseEC:2.8.1.7
Prokaryotic defense systemko02048deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_066920621.1 across 40 RNA-seq samples of Clytia hemisphaerica. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

40Samples
40TPM > 0
16Conditions
109.6Max TPM
73.0Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Mature medusa 5 5 101.63 109.11
medusa · Experiment Condition A1 4 4 52.95 58.97
medusa · Experiment Condition A2 4 4 47.96 50.34
medusa · Experiment Condition A3 4 4 82.23 83.45
Early gastrula 2 2 50.28 52.36
Planula 24hpf 2 2 64.80 67.54
Planula 48hpf 2 2 66.13 67.81
Planula 72hpf 2 2 83.71 93.68
Primary polyp 2 2 57.34 59.59
Gastrozooid 2 2 38.97 39.02
Gonozooid 2 2 106.67 109.25
Stolon 2 2 66.78 75.32
Baby medusa 2 2 106.10 109.60
medusa · Experiment Condition B1 2 2 95.59 96.39
medusa · Experiment Condition B2 2 2 58.36 58.52
Mixed 1 1 89.01 89.01

Per sample · hover a bar for the full sample record

Show the sample table (40 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
ERR2816251 Mature medusa not recorded Mature medusa not recorded ERP110164 109.11
ERR2816250 Mature medusa not recorded Mature medusa not recorded ERP110164 108.95
ERR2816248 Mature medusa not recorded Mature medusa not recorded ERP110164 99.39
ERR2816249 Mature medusa not recorded Mature medusa not recorded ERP110164 95.57
ERR2862245 Mature medusa not recorded Mature medusa not recorded ERP110164 95.12
ERR3299475 medusa · Experiment Condition A1 not recorded medusa Experiment Condition A1 ERP115020 58.97
ERR3299476 medusa · Experiment Condition A1 not recorded medusa Experiment Condition A1 ERP115020 56.61
ERR3299478 medusa · Experiment Condition A1 not recorded medusa Experiment Condition A1 ERP115020 48.19
ERR3299477 medusa · Experiment Condition A1 not recorded medusa Experiment Condition A1 ERP115020 48.01
ERR3299480 medusa · Experiment Condition A2 not recorded medusa Experiment Condition A2 ERP115020 50.34
ERR3299482 medusa · Experiment Condition A2 not recorded medusa Experiment Condition A2 ERP115020 48.84
ERR3299479 medusa · Experiment Condition A2 not recorded medusa Experiment Condition A2 ERP115020 47.14
ERR3299481 medusa · Experiment Condition A2 not recorded medusa Experiment Condition A2 ERP115020 45.51
ERR3299485 medusa · Experiment Condition A3 not recorded medusa Experiment Condition A3 ERP115020 83.45
ERR3299484 medusa · Experiment Condition A3 not recorded medusa Experiment Condition A3 ERP115020 82.45
ERR3299486 medusa · Experiment Condition A3 not recorded medusa Experiment Condition A3 ERP115020 82.40
ERR3299483 medusa · Experiment Condition A3 not recorded medusa Experiment Condition A3 ERP115020 80.61
ERR2816230 Early gastrula not recorded Early gastrula not recorded ERP110164 52.36
ERR2816231 Early gastrula not recorded Early gastrula not recorded ERP110164 48.20
ERR2816233 Planula 24hpf not recorded Planula 24hpf not recorded ERP110164 67.54
ERR2816232 Planula 24hpf not recorded Planula 24hpf not recorded ERP110164 62.07
ERR2816235 Planula 48hpf not recorded Planula 48hpf not recorded ERP110164 67.81
ERR2816234 Planula 48hpf not recorded Planula 48hpf not recorded ERP110164 64.44
ERR2816236 Planula 72hpf not recorded Planula 72hpf not recorded ERP110164 93.68
ERR2816237 Planula 72hpf not recorded Planula 72hpf not recorded ERP110164 73.75
ERR2816238 Primary polyp not recorded Primary polyp not recorded ERP110164 59.59
ERR2816239 Primary polyp not recorded Primary polyp not recorded ERP110164 55.09
ERR2816241 Gastrozooid not recorded Gastrozooid not recorded ERP110164 39.02
ERR2816240 Gastrozooid not recorded Gastrozooid not recorded ERP110164 38.92
ERR2816243 Gonozooid not recorded Gonozooid not recorded ERP110164 109.25
ERR2816242 Gonozooid not recorded Gonozooid not recorded ERP110164 104.09
ERR2816245 Stolon not recorded Stolon not recorded ERP110164 75.32
ERR2816244 Stolon not recorded Stolon not recorded ERP110164 58.24
ERR2816247 Baby medusa not recorded Baby medusa not recorded ERP110164 109.60
ERR2816246 Baby medusa not recorded Baby medusa not recorded ERP110164 102.60
ERR3299472 medusa · Experiment Condition B1 not recorded medusa Experiment Condition B1 ERP115020 96.39
ERR3299471 medusa · Experiment Condition B1 not recorded medusa Experiment Condition B1 ERP115020 94.79
ERR3299473 medusa · Experiment Condition B2 not recorded medusa Experiment Condition B2 ERP115020 58.52
ERR3299474 medusa · Experiment Condition B2 not recorded medusa Experiment Condition B2 ERP115020 58.21
ERR2862244 Mixed not recorded Mixed not recorded ERP110164 89.01

Source: CnidoSite RNA-seq expression matrices (CHEMI_TPM, StringTie quantification over 40 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Clytia hemisphaerica tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated15XP_066927676.10.857194001783077
Negatively correlated9XP_066933507.1-0.704510080448547

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Clytia hemisphaerica, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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