Gene detail

Detailed information of XP_066929261.1 in Clytia hemisphaerica

Genomic Location: NW_027104275.1:289325...299149
NR annotation: XP_012557554.1, glutamate--cysteine ligase regulatory subunit [Hydra vulgaris]

Gene Structure

More details in Jbrowse

Sequence

CDS

Transcript

Protein

Uniprot

Uniprot term	Description
P48507	Glutamate--cysteine ligase regulatory subunit OS=Homo sapiens OX=9606 GN=GCLM PE=1 SV=1
P48508	Glutamate--cysteine ligase regulatory subunit OS=Rattus norvegicus OX=10116 GN=Gclm PE=1 SV=1
O09172	Glutamate--cysteine ligase regulatory subunit OS=Mus musculus OX=10090 GN=Gclm PE=1 SV=1

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00248	Aldo_ket_red	Aldo/keto reductase family	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR032963	Family	Glutamate--cysteine ligase regulatory subunit	Interproscan
IPR036812	Homologous_superfamily	NADP-dependent oxidoreductase domain superfamily	Interproscan
IPR023210	Domain	NADP-dependent oxidoreductase domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13295	GLUTAMATE CYSTEINE LIGASE REGULATORY SUBUNIT	Interproscan

Gene Ontology

GO terms	Category	Description	Source
GO:0006750	Biological Process	glutathione biosynthetic process	Interproscan
GO:0017109	Cellular Component	glutamate-cysteine ligase complex	Interproscan
GO:0030234	Molecular Function	enzyme regulator activity	Interproscan
GO:0035226	Molecular Function	glutamate-cysteine ligase catalytic subunit binding	Interproscan
GO:0035229	Biological Process	positive regulation of glutamate-cysteine ligase activity	Interproscan

KEGG pathway

KO	Enzyme	Enzyme ID	pathway	mapID	Source
K11205	GCLM; glutamate--cysteine ligase regulatory subunit	-	Ferroptosis	ko04216	deepkoala