Genomic Location: NW_027104383.1:167404...195566
NR annotation: XP_047132289.1, talin-2 isoform X2 [Hydra vulgaris]
Species Clytia hemisphaerica · all data for this species · gene families
| CDS |
| XP_066931569.1 |
| Protein |
| XP_066931569.1 |
| UniProt accession | Description |
|---|---|
| Q9Y4G6 | Talin-2 OS=Homo sapiens OX=9606 GN=TLN2 PE=1 SV=4 |
| P54939 | Talin-1 OS=Gallus gallus OX=9031 GN=TLN1 PE=1 SV=2 |
| A0A3G2LGI8 | Talin OS=Oscarella pearsei OX=1940113 GN=TLN PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001942 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF09141 all species → | Talin_middle | Talin, middle domain | Domain | Interproscan |
| PF21692 all species → | Talin_R4 | Talin, R4 domain | Domain | Interproscan |
| PF01608 all species → | I_LWEQ | I/LWEQ domain | Family | Interproscan |
| PF00373 all species → | FERM_M | FERM central domain | Domain | Interproscan |
| PF16511 all species → | FERM_f0 | N-terminal or F0 domain of Talin-head FERM | Domain | Interproscan |
| PF08913 all species → | VBS | Vinculin Binding Site | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR019748 all species → | Domain | FERM central domain | Interproscan |
| IPR036476 all species → | Homologous_superfamily | Talin, central domain superfamily | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR035964 all species → | Homologous_superfamily | I/LWEQ domain superfamily | Interproscan |
| IPR000299 all species → | Domain | FERM domain | Interproscan |
| IPR015224 all species → | Domain | Talin, central | Interproscan |
| IPR036723 all species → | Homologous_superfamily | Alpha-catenin/vinculin-like superfamily | Interproscan |
| IPR049108 all species → | Domain | Talin, R4 domain | Interproscan |
| IPR019747 all species → | Conserved_site | FERM conserved site | Interproscan |
| IPR037438 all species → | Domain | Talin-1/2, rod-segment | Interproscan |
| IPR002558 all species → | Domain | I/LWEQ domain | Interproscan |
| IPR035963 all species → | Homologous_superfamily | FERM superfamily, second domain | Interproscan |
| IPR019749 all species → | Domain | Band 4.1 domain | Interproscan |
| IPR032425 all species → | Domain | Talin, N-terminal F0 domain | Interproscan |
| IPR015009 all species → | Domain | Vinculin-binding site-containing domain | Interproscan |
| IPR014352 all species → | Homologous_superfamily | FERM/acyl-CoA-binding protein superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR19981 all species → | TALIN | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003779 all species → | Molecular Function | actin binding | Interproscan |
| GO:0005856 all species → | Cellular Component | cytoskeleton | Interproscan |
| GO:0001726 all species → | Cellular Component | ruffle | Interproscan |
| GO:0005200 all species → | Molecular Function | structural constituent of cytoskeleton | Interproscan |
| GO:0005925 all species → | Cellular Component | focal adhesion | Interproscan |
| GO:0007155 all species → | Biological Process | cell adhesion | Interproscan |
| GO:0051015 all species → | Molecular Function | actin filament binding | Interproscan |
| GO:0005178 all species → | Molecular Function | integrin binding | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0098609 all species → | Biological Process | cell-cell adhesion | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K06271 | TLN; talin | - | Exosome | ko04147 | deepkoala |
Transcript abundance of XP_066931569.1 across 40 RNA-seq samples of Clytia hemisphaerica. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Mature medusa | 5 | 0 | 0.00 | 0.00 | |
| medusa · Experiment Condition A1 | 4 | 0 | 0.00 | 0.00 | |
| medusa · Experiment Condition A2 | 4 | 0 | 0.00 | 0.00 | |
| medusa · Experiment Condition A3 | 4 | 0 | 0.00 | 0.00 | |
| Early gastrula | 2 | 0 | 0.00 | 0.00 | |
| Planula 24hpf | 2 | 0 | 0.00 | 0.00 | |
| Planula 48hpf | 2 | 0 | 0.00 | 0.00 | |
| Planula 72hpf | 2 | 0 | 0.00 | 0.00 | |
| Primary polyp | 2 | 0 | 0.00 | 0.00 | |
| Gastrozooid | 2 | 0 | 0.00 | 0.00 | |
| Gonozooid | 2 | 0 | 0.00 | 0.00 | |
| Stolon | 2 | 0 | 0.00 | 0.00 | |
| Baby medusa | 2 | 0 | 0.00 | 0.00 | |
| medusa · Experiment Condition B1 | 2 | 0 | 0.00 | 0.00 | |
| medusa · Experiment Condition B2 | 2 | 0 | 0.00 | 0.00 | |
| Mixed | 1 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| ERR2816248 | Mature medusa | not recorded | Mature medusa | not recorded | ERP110164 | 0.00 |
| ERR2816249 | Mature medusa | not recorded | Mature medusa | not recorded | ERP110164 | 0.00 |
| ERR2816250 | Mature medusa | not recorded | Mature medusa | not recorded | ERP110164 | 0.00 |
| ERR2816251 | Mature medusa | not recorded | Mature medusa | not recorded | ERP110164 | 0.00 |
| ERR2862245 | Mature medusa | not recorded | Mature medusa | not recorded | ERP110164 | 0.00 |
| ERR3299475 | medusa · Experiment Condition A1 | not recorded | medusa | Experiment Condition A1 | ERP115020 | 0.00 |
| ERR3299476 | medusa · Experiment Condition A1 | not recorded | medusa | Experiment Condition A1 | ERP115020 | 0.00 |
| ERR3299477 | medusa · Experiment Condition A1 | not recorded | medusa | Experiment Condition A1 | ERP115020 | 0.00 |
| ERR3299478 | medusa · Experiment Condition A1 | not recorded | medusa | Experiment Condition A1 | ERP115020 | 0.00 |
| ERR3299479 | medusa · Experiment Condition A2 | not recorded | medusa | Experiment Condition A2 | ERP115020 | 0.00 |
| ERR3299480 | medusa · Experiment Condition A2 | not recorded | medusa | Experiment Condition A2 | ERP115020 | 0.00 |
| ERR3299481 | medusa · Experiment Condition A2 | not recorded | medusa | Experiment Condition A2 | ERP115020 | 0.00 |
| ERR3299482 | medusa · Experiment Condition A2 | not recorded | medusa | Experiment Condition A2 | ERP115020 | 0.00 |
| ERR3299483 | medusa · Experiment Condition A3 | not recorded | medusa | Experiment Condition A3 | ERP115020 | 0.00 |
| ERR3299484 | medusa · Experiment Condition A3 | not recorded | medusa | Experiment Condition A3 | ERP115020 | 0.00 |
| ERR3299485 | medusa · Experiment Condition A3 | not recorded | medusa | Experiment Condition A3 | ERP115020 | 0.00 |
| ERR3299486 | medusa · Experiment Condition A3 | not recorded | medusa | Experiment Condition A3 | ERP115020 | 0.00 |
| ERR2816230 | Early gastrula | not recorded | Early gastrula | not recorded | ERP110164 | 0.00 |
| ERR2816231 | Early gastrula | not recorded | Early gastrula | not recorded | ERP110164 | 0.00 |
| ERR2816232 | Planula 24hpf | not recorded | Planula 24hpf | not recorded | ERP110164 | 0.00 |
| ERR2816233 | Planula 24hpf | not recorded | Planula 24hpf | not recorded | ERP110164 | 0.00 |
| ERR2816234 | Planula 48hpf | not recorded | Planula 48hpf | not recorded | ERP110164 | 0.00 |
| ERR2816235 | Planula 48hpf | not recorded | Planula 48hpf | not recorded | ERP110164 | 0.00 |
| ERR2816236 | Planula 72hpf | not recorded | Planula 72hpf | not recorded | ERP110164 | 0.00 |
| ERR2816237 | Planula 72hpf | not recorded | Planula 72hpf | not recorded | ERP110164 | 0.00 |
| ERR2816238 | Primary polyp | not recorded | Primary polyp | not recorded | ERP110164 | 0.00 |
| ERR2816239 | Primary polyp | not recorded | Primary polyp | not recorded | ERP110164 | 0.00 |
| ERR2816240 | Gastrozooid | not recorded | Gastrozooid | not recorded | ERP110164 | 0.00 |
| ERR2816241 | Gastrozooid | not recorded | Gastrozooid | not recorded | ERP110164 | 0.00 |
| ERR2816242 | Gonozooid | not recorded | Gonozooid | not recorded | ERP110164 | 0.00 |
| ERR2816243 | Gonozooid | not recorded | Gonozooid | not recorded | ERP110164 | 0.00 |
| ERR2816244 | Stolon | not recorded | Stolon | not recorded | ERP110164 | 0.00 |
| ERR2816245 | Stolon | not recorded | Stolon | not recorded | ERP110164 | 0.00 |
| ERR2816246 | Baby medusa | not recorded | Baby medusa | not recorded | ERP110164 | 0.00 |
| ERR2816247 | Baby medusa | not recorded | Baby medusa | not recorded | ERP110164 | 0.00 |
| ERR3299471 | medusa · Experiment Condition B1 | not recorded | medusa | Experiment Condition B1 | ERP115020 | 0.00 |
| ERR3299472 | medusa · Experiment Condition B1 | not recorded | medusa | Experiment Condition B1 | ERP115020 | 0.00 |
| ERR3299473 | medusa · Experiment Condition B2 | not recorded | medusa | Experiment Condition B2 | ERP115020 | 0.00 |
| ERR3299474 | medusa · Experiment Condition B2 | not recorded | medusa | Experiment Condition B2 | ERP115020 | 0.00 |
| ERR2862244 | Mixed | not recorded | Mixed | not recorded | ERP110164 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (CHEMI_TPM,
StringTie quantification over 40 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Clytia hemisphaerica tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Clytia hemisphaerica network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Clytia hemisphaerica, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
