Genomic Location: NW_027104558.1:390788...445044
NR annotation: XP_047122575.1, adhesion G protein-coupled receptor L2-like isoform X2 [Hydra vulgaris]
Species Clytia hemisphaerica · all data for this species · gene families
| CDS |
| XP_066935399.1 |
| Protein |
| XP_066935399.1 |
| UniProt accession | Description |
|---|---|
| Q9HAR2 | Adhesion G protein-coupled receptor L3 OS=Homo sapiens OX=9606 GN=ADGRL3 PE=1 SV=2 |
| Q9Z173 | Adhesion G protein-coupled receptor L3 OS=Rattus norvegicus OX=10116 GN=Adgrl3 PE=1 SV=1 |
| O97827 | Adhesion G protein-coupled receptor L3 OS=Bos taurus OX=9913 GN=ADGRL3 PE=2 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0000036 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00002 all species → | 7tm_2 | 7 transmembrane receptor (Secretin family) | Family | Interproscan |
| PF07645 all species → | EGF_CA | Calcium-binding EGF domain | Domain | Interproscan |
| PF02793 all species → | HRM | Hormone receptor domain | Family | Interproscan |
| PF16489 all species → | GAIN | GPCR-Autoproteolysis INducing (GAIN) domain | Domain | Interproscan |
| PF01825 all species → | GPS | GPCR proteolysis site, GPS, motif | Motif | Interproscan |
| PF13385 all species → | Laminin_G_3 | Concanavalin A-like lectin/glucanases superfamily | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR001879 all species → | Domain | GPCR, family 2, extracellular hormone receptor domain | Interproscan |
| IPR000832 all species → | Family | GPCR, family 2, secretin-like | Interproscan |
| IPR013783 all species → | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR049883 all species → | Domain | NOTCH1 EGF-like calcium-binding domain | Interproscan |
| IPR000742 all species → | Domain | EGF-like domain | Interproscan |
| IPR001881 all species → | Domain | EGF-like calcium-binding domain | Interproscan |
| IPR003961 all species → | Domain | Fibronectin type III | Interproscan |
| IPR018097 all species → | Conserved_site | EGF-like calcium-binding, conserved site | Interproscan |
| IPR036445 all species → | Homologous_superfamily | GPCR family 2, extracellular hormone receptor domain superfamily | Interproscan |
| IPR000203 all species → | Conserved_site | GPS motif | Interproscan |
| IPR032471 all species → | Domain | GAIN domain, N-terminal | Interproscan |
| IPR036116 all species → | Homologous_superfamily | Fibronectin type III superfamily | Interproscan |
| IPR046338 all species → | Homologous_superfamily | GAIN domain superfamily | Interproscan |
| IPR000152 all species → | PTM | EGF-type aspartate/asparagine hydroxylation site | Interproscan |
| IPR013320 all species → | Homologous_superfamily | Concanavalin A-like lectin/glucanase domain superfamily | Interproscan |
| IPR009030 all species → | Homologous_superfamily | Growth factor receptor cysteine-rich domain superfamily | Interproscan |
| IPR017981 all species → | Domain | GPCR, family 2-like, 7TM | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR12011 all species → | ADHESION G-PROTEIN COUPLED RECEPTOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004930 all species → | Molecular Function | G protein-coupled receptor activity | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0007186 all species → | Biological Process | G protein-coupled receptor signaling pathway | Interproscan |
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005887 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007189 all species → | Biological Process | adenylate cyclase-activating G protein-coupled receptor signaling pathway | Interproscan |
| GO:0004888 all species → | Molecular Function | transmembrane signaling receptor activity | Interproscan |
| GO:0007166 all species → | Biological Process | cell surface receptor signaling pathway | Interproscan |
XP_066935399.1.Transcript abundance of XP_066935399.1 across 40 RNA-seq samples of Clytia hemisphaerica. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Mature medusa | 5 | 0 | 0.00 | 0.00 | |
| medusa · Experiment Condition A1 | 4 | 0 | 0.00 | 0.00 | |
| medusa · Experiment Condition A2 | 4 | 0 | 0.00 | 0.00 | |
| medusa · Experiment Condition A3 | 4 | 0 | 0.00 | 0.00 | |
| Early gastrula | 2 | 0 | 0.00 | 0.00 | |
| Planula 24hpf | 2 | 0 | 0.00 | 0.00 | |
| Planula 48hpf | 2 | 0 | 0.00 | 0.00 | |
| Planula 72hpf | 2 | 0 | 0.00 | 0.00 | |
| Primary polyp | 2 | 0 | 0.00 | 0.00 | |
| Gastrozooid | 2 | 0 | 0.00 | 0.00 | |
| Gonozooid | 2 | 0 | 0.00 | 0.00 | |
| Stolon | 2 | 0 | 0.00 | 0.00 | |
| Baby medusa | 2 | 0 | 0.00 | 0.00 | |
| medusa · Experiment Condition B1 | 2 | 0 | 0.00 | 0.00 | |
| medusa · Experiment Condition B2 | 2 | 0 | 0.00 | 0.00 | |
| Mixed | 1 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| ERR2816248 | Mature medusa | not recorded | Mature medusa | not recorded | ERP110164 | 0.00 |
| ERR2816249 | Mature medusa | not recorded | Mature medusa | not recorded | ERP110164 | 0.00 |
| ERR2816250 | Mature medusa | not recorded | Mature medusa | not recorded | ERP110164 | 0.00 |
| ERR2816251 | Mature medusa | not recorded | Mature medusa | not recorded | ERP110164 | 0.00 |
| ERR2862245 | Mature medusa | not recorded | Mature medusa | not recorded | ERP110164 | 0.00 |
| ERR3299475 | medusa · Experiment Condition A1 | not recorded | medusa | Experiment Condition A1 | ERP115020 | 0.00 |
| ERR3299476 | medusa · Experiment Condition A1 | not recorded | medusa | Experiment Condition A1 | ERP115020 | 0.00 |
| ERR3299477 | medusa · Experiment Condition A1 | not recorded | medusa | Experiment Condition A1 | ERP115020 | 0.00 |
| ERR3299478 | medusa · Experiment Condition A1 | not recorded | medusa | Experiment Condition A1 | ERP115020 | 0.00 |
| ERR3299479 | medusa · Experiment Condition A2 | not recorded | medusa | Experiment Condition A2 | ERP115020 | 0.00 |
| ERR3299480 | medusa · Experiment Condition A2 | not recorded | medusa | Experiment Condition A2 | ERP115020 | 0.00 |
| ERR3299481 | medusa · Experiment Condition A2 | not recorded | medusa | Experiment Condition A2 | ERP115020 | 0.00 |
| ERR3299482 | medusa · Experiment Condition A2 | not recorded | medusa | Experiment Condition A2 | ERP115020 | 0.00 |
| ERR3299483 | medusa · Experiment Condition A3 | not recorded | medusa | Experiment Condition A3 | ERP115020 | 0.00 |
| ERR3299484 | medusa · Experiment Condition A3 | not recorded | medusa | Experiment Condition A3 | ERP115020 | 0.00 |
| ERR3299485 | medusa · Experiment Condition A3 | not recorded | medusa | Experiment Condition A3 | ERP115020 | 0.00 |
| ERR3299486 | medusa · Experiment Condition A3 | not recorded | medusa | Experiment Condition A3 | ERP115020 | 0.00 |
| ERR2816230 | Early gastrula | not recorded | Early gastrula | not recorded | ERP110164 | 0.00 |
| ERR2816231 | Early gastrula | not recorded | Early gastrula | not recorded | ERP110164 | 0.00 |
| ERR2816232 | Planula 24hpf | not recorded | Planula 24hpf | not recorded | ERP110164 | 0.00 |
| ERR2816233 | Planula 24hpf | not recorded | Planula 24hpf | not recorded | ERP110164 | 0.00 |
| ERR2816234 | Planula 48hpf | not recorded | Planula 48hpf | not recorded | ERP110164 | 0.00 |
| ERR2816235 | Planula 48hpf | not recorded | Planula 48hpf | not recorded | ERP110164 | 0.00 |
| ERR2816236 | Planula 72hpf | not recorded | Planula 72hpf | not recorded | ERP110164 | 0.00 |
| ERR2816237 | Planula 72hpf | not recorded | Planula 72hpf | not recorded | ERP110164 | 0.00 |
| ERR2816238 | Primary polyp | not recorded | Primary polyp | not recorded | ERP110164 | 0.00 |
| ERR2816239 | Primary polyp | not recorded | Primary polyp | not recorded | ERP110164 | 0.00 |
| ERR2816240 | Gastrozooid | not recorded | Gastrozooid | not recorded | ERP110164 | 0.00 |
| ERR2816241 | Gastrozooid | not recorded | Gastrozooid | not recorded | ERP110164 | 0.00 |
| ERR2816242 | Gonozooid | not recorded | Gonozooid | not recorded | ERP110164 | 0.00 |
| ERR2816243 | Gonozooid | not recorded | Gonozooid | not recorded | ERP110164 | 0.00 |
| ERR2816244 | Stolon | not recorded | Stolon | not recorded | ERP110164 | 0.00 |
| ERR2816245 | Stolon | not recorded | Stolon | not recorded | ERP110164 | 0.00 |
| ERR2816246 | Baby medusa | not recorded | Baby medusa | not recorded | ERP110164 | 0.00 |
| ERR2816247 | Baby medusa | not recorded | Baby medusa | not recorded | ERP110164 | 0.00 |
| ERR3299471 | medusa · Experiment Condition B1 | not recorded | medusa | Experiment Condition B1 | ERP115020 | 0.00 |
| ERR3299472 | medusa · Experiment Condition B1 | not recorded | medusa | Experiment Condition B1 | ERP115020 | 0.00 |
| ERR3299473 | medusa · Experiment Condition B2 | not recorded | medusa | Experiment Condition B2 | ERP115020 | 0.00 |
| ERR3299474 | medusa · Experiment Condition B2 | not recorded | medusa | Experiment Condition B2 | ERP115020 | 0.00 |
| ERR2862244 | Mixed | not recorded | Mixed | not recorded | ERP110164 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (CHEMI_TPM,
StringTie quantification over 40 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Clytia hemisphaerica tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Clytia hemisphaerica network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Clytia hemisphaerica, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
