Detailed information of XP_068688613.1 in Montipora foliosa

Genomic Location: chr14:5339236...5352293
NR annotation: XP_015758070.1, PREDICTED: DNA polymerase eta-like [Acropora digitifera]
Species Montipora foliosa · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q9JJN0DNA polymerase eta OS=Mus musculus OX=10090 GN=Polh PE=1 SV=1
Q9Y253DNA polymerase eta OS=Homo sapiens OX=9606 GN=POLH PE=1 SV=1
Q8H2D5DNA polymerase eta OS=Arabidopsis thaliana OX=3702 GN=POLH PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0005757 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF21704
all species →
POLH-Rev1_HhHDNApol eta/Rev1, HhH motifMotifInterproscan
PF11799
all species →
IMS_CimpB/mucB/samB family C-terminal domainDomainInterproscan
PF18439
all species →
zf_UBZUbiquitin-Binding Zinc FingerDomainInterproscan
PF00817
all species →
IMSimpB/mucB/samB familyFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR036775
all species →
Homologous_superfamilyDNA polymerase, Y-family, little finger domain superfamilyInterproscan
IPR001126
all species →
DomainUmuC domainInterproscan
IPR041298
all species →
DomainDNA polymerase eta, ubiquitin-binding zinc fingerInterproscan
IPR043128
all species →
Homologous_superfamilyReverse transcriptase/Diguanylate cyclase domainInterproscan
IPR017961
all species →
DomainDNA polymerase, Y-family, little finger domainInterproscan
IPR043502
all species →
Homologous_superfamilyDNA/RNA polymerase superfamilyInterproscan
IPR052230
all species →
FamilyDNA polymerase etaInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR45873
all species →
DNA POLYMERASE ETAInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0003684
all species →
Molecular Functiondamaged DNA bindingInterproscan
GO:0006281
all species →
Biological ProcessDNA repairInterproscan
GO:0003887
all species →
Molecular FunctionDNA-directed DNA polymerase activityInterproscan
GO:0005634
all species →
Cellular ComponentnucleusInterproscan
GO:0005657
all species →
Cellular Componentreplication forkInterproscan
GO:0009314
all species →
Biological Processresponse to radiationInterproscan
GO:0035861
all species →
Cellular Componentsite of double-strand breakInterproscan
GO:0042276
all species →
Biological Processerror-prone translesion synthesisInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K03509POLH; DNA polymerase etaEC:2.7.7.7
DNA repair and recombination proteinsko03400deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068688613.1 across 36 RNA-seq samples of Montipora foliosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples
26TPM > 0
1Conditions
6.7Max TPM
1.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Polyps 36 26 1.53 6.71

Per sample · hover a bar for the full sample record

Show the sample table (36 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR12786903 Polyps Polyps OA4 day0 not recorded SRP199550 6.71
SRR12786904 Polyps Polyps OA4 day0 not recorded SRP199550 4.42
SRR12786895 Polyps Polyps OA4 day0 not recorded SRP199550 3.46
SRR12904780 Polyps Polyps not recorded not recorded SRP199550 2.31
SRR27940180 Polyps Polyps not recorded not recorded SRP199550 2.28
SRR12959226 Polyps Polyps E4 day3 not recorded SRP199550 2.18
SRR12959224 Polyps Polyps E4 day3 not recorded SRP199550 2.17
SRR12710865 Polyps Polyps OA4 day3 not recorded SRP199550 2.17
SRR12904791 Polyps Polyps not recorded not recorded SRP199550 2.17
SRR27940177 Polyps Polyps not recorded not recorded SRP199550 2.16
SRR12959181 Polyps Polyps E4 day0 not recorded SRP199550 2.07
SRR12959225 Polyps Polyps E4 day3 not recorded SRP199550 2.06
SRR12710852 Polyps Polyps OA4 day9 not recorded SRP199550 1.98
SRR12959198 Polyps Polyps E4 day15 not recorded SRP199550 1.91
SRR12959238 Polyps Polyps E4 day0 not recorded SRP199550 1.90
SRR12959199 Polyps Polyps E4 day15 not recorded SRP199550 1.85
SRR12959237 Polyps Polyps E4 day0 not recorded SRP199550 1.61
SRR12959200 Polyps Polyps E4 day15 not recorded SRP199550 1.60
SRR12959213 Polyps Polyps E4 day9 not recorded SRP199550 1.52
SRR12710866 Polyps Polyps OA4 day3 not recorded SRP199550 1.50
SRR12710853 Polyps Polyps OA4 day9 not recorded SRP199550 1.45
SRR12959212 Polyps Polyps E4 day9 not recorded SRP199550 1.40
SRR12904792 Polyps Polyps not recorded not recorded SRP199550 1.33
SRR27940179 Polyps Polyps not recorded not recorded SRP199550 1.31
SRR12959186 Polyps Polyps E4 day21 not recorded SRP199550 1.05
SRR12959187 Polyps Polyps E4 day21 not recorded SRP199550 0.59
SRR12710845 Polyps Polyps OA4 day3 not recorded SRP199550 0.00
SRR12710854 Polyps Polyps OA4 day9 not recorded SRP199550 0.00
SRR12807380 Polyps Polyps OA4 day0 not recorded SRP199550 0.00
SRR12849112 Polyps Polyps OA4 day0 not recorded SRP199550 0.00
SRR12927879 Polyps Polyps E4 day0 not recorded SRP199550 0.00
SRR12959185 Polyps Polyps E4 day21 not recorded SRP199550 0.00
SRR12959211 Polyps Polyps E4 day9 not recorded SRP199550 0.00
SRR12963483 Polyps Polyps E4 day0 not recorded SRP199550 0.00
SRR9129315 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613518 Polyps Polyps not recorded not recorded SRP199550 0.00

Source: CnidoSite RNA-seq expression matrices (MFOLI_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora foliosa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated27XP_068673274.10.965650646911944
Negatively correlated3XP_068681185.1-0.311654610311115

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora foliosa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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