Genomic Location: chr14:5339236...5352293
NR annotation: XP_015758070.1, PREDICTED: DNA polymerase eta-like [Acropora digitifera]
Species Montipora foliosa · all data for this species · gene families
| CDS |
| LOC137985064 |
| Transcript |
| rna-XM_068832512.1 |
| Protein |
| XP_068688613.1 |
| UniProt accession | Description |
|---|---|
| Q9JJN0 | DNA polymerase eta OS=Mus musculus OX=10090 GN=Polh PE=1 SV=1 |
| Q9Y253 | DNA polymerase eta OS=Homo sapiens OX=9606 GN=POLH PE=1 SV=1 |
| Q8H2D5 | DNA polymerase eta OS=Arabidopsis thaliana OX=3702 GN=POLH PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005757 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF21704 all species → | POLH-Rev1_HhH | DNApol eta/Rev1, HhH motif | Motif | Interproscan |
| PF11799 all species → | IMS_C | impB/mucB/samB family C-terminal domain | Domain | Interproscan |
| PF18439 all species → | zf_UBZ | Ubiquitin-Binding Zinc Finger | Domain | Interproscan |
| PF00817 all species → | IMS | impB/mucB/samB family | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR036775 all species → | Homologous_superfamily | DNA polymerase, Y-family, little finger domain superfamily | Interproscan |
| IPR001126 all species → | Domain | UmuC domain | Interproscan |
| IPR041298 all species → | Domain | DNA polymerase eta, ubiquitin-binding zinc finger | Interproscan |
| IPR043128 all species → | Homologous_superfamily | Reverse transcriptase/Diguanylate cyclase domain | Interproscan |
| IPR017961 all species → | Domain | DNA polymerase, Y-family, little finger domain | Interproscan |
| IPR043502 all species → | Homologous_superfamily | DNA/RNA polymerase superfamily | Interproscan |
| IPR052230 all species → | Family | DNA polymerase eta | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR45873 all species → | DNA POLYMERASE ETA | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0003684 all species → | Molecular Function | damaged DNA binding | Interproscan |
| GO:0006281 all species → | Biological Process | DNA repair | Interproscan |
| GO:0003887 all species → | Molecular Function | DNA-directed DNA polymerase activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005657 all species → | Cellular Component | replication fork | Interproscan |
| GO:0009314 all species → | Biological Process | response to radiation | Interproscan |
| GO:0035861 all species → | Cellular Component | site of double-strand break | Interproscan |
| GO:0042276 all species → | Biological Process | error-prone translesion synthesis | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K03509 | POLH; DNA polymerase eta | EC:2.7.7.7 | DNA repair and recombination proteins | ko03400 | deepkoala |
Transcript abundance of XP_068688613.1 across 36 RNA-seq samples of Montipora foliosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 36 | 26 | 1.53 | 6.71 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR12786903 | Polyps | Polyps | OA4 day0 | not recorded | SRP199550 | 6.71 |
| SRR12786904 | Polyps | Polyps | OA4 day0 | not recorded | SRP199550 | 4.42 |
| SRR12786895 | Polyps | Polyps | OA4 day0 | not recorded | SRP199550 | 3.46 |
| SRR12904780 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 2.31 |
| SRR27940180 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 2.28 |
| SRR12959226 | Polyps | Polyps | E4 day3 | not recorded | SRP199550 | 2.18 |
| SRR12959224 | Polyps | Polyps | E4 day3 | not recorded | SRP199550 | 2.17 |
| SRR12710865 | Polyps | Polyps | OA4 day3 | not recorded | SRP199550 | 2.17 |
| SRR12904791 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 2.17 |
| SRR27940177 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 2.16 |
| SRR12959181 | Polyps | Polyps | E4 day0 | not recorded | SRP199550 | 2.07 |
| SRR12959225 | Polyps | Polyps | E4 day3 | not recorded | SRP199550 | 2.06 |
| SRR12710852 | Polyps | Polyps | OA4 day9 | not recorded | SRP199550 | 1.98 |
| SRR12959198 | Polyps | Polyps | E4 day15 | not recorded | SRP199550 | 1.91 |
| SRR12959238 | Polyps | Polyps | E4 day0 | not recorded | SRP199550 | 1.90 |
| SRR12959199 | Polyps | Polyps | E4 day15 | not recorded | SRP199550 | 1.85 |
| SRR12959237 | Polyps | Polyps | E4 day0 | not recorded | SRP199550 | 1.61 |
| SRR12959200 | Polyps | Polyps | E4 day15 | not recorded | SRP199550 | 1.60 |
| SRR12959213 | Polyps | Polyps | E4 day9 | not recorded | SRP199550 | 1.52 |
| SRR12710866 | Polyps | Polyps | OA4 day3 | not recorded | SRP199550 | 1.50 |
| SRR12710853 | Polyps | Polyps | OA4 day9 | not recorded | SRP199550 | 1.45 |
| SRR12959212 | Polyps | Polyps | E4 day9 | not recorded | SRP199550 | 1.40 |
| SRR12904792 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 1.33 |
| SRR27940179 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 1.31 |
| SRR12959186 | Polyps | Polyps | E4 day21 | not recorded | SRP199550 | 1.05 |
| SRR12959187 | Polyps | Polyps | E4 day21 | not recorded | SRP199550 | 0.59 |
| SRR12710845 | Polyps | Polyps | OA4 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710854 | Polyps | Polyps | OA4 day9 | not recorded | SRP199550 | 0.00 |
| SRR12807380 | Polyps | Polyps | OA4 day0 | not recorded | SRP199550 | 0.00 |
| SRR12849112 | Polyps | Polyps | OA4 day0 | not recorded | SRP199550 | 0.00 |
| SRR12927879 | Polyps | Polyps | E4 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959185 | Polyps | Polyps | E4 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959211 | Polyps | Polyps | E4 day9 | not recorded | SRP199550 | 0.00 |
| SRR12963483 | Polyps | Polyps | E4 day0 | not recorded | SRP199550 | 0.00 |
| SRR9129315 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613518 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (MFOLI_TPM,
StringTie quantification over 36 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora foliosa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 27 | XP_068673274.1 | 0.965650646911944 |
| Negatively correlated | 3 | XP_068681185.1 | -0.311654610311115 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora foliosa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |