Gene detail

Detailed information of XP_068700545.1 in Montipora foliosa

Genomic Location: chr3:66905241...66917340
NR annotation: XP_015754209.1, PREDICTED: F-actin-capping protein subunit beta-like [Acropora digitifera]
Species Montipora foliosa · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P47756	F-actin-capping protein subunit beta OS=Homo sapiens OX=9606 GN=CAPZB PE=1 SV=5
A0PFK7	F-actin-capping protein subunit beta OS=Sus scrofa OX=9823 GN=CAPZB PE=1 SV=2
Q5R507	F-actin-capping protein subunit beta OS=Pongo abelii OX=9601 GN=CAPZB PE=2 SV=2

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0007378 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF01115 all species →	F_actin_cap_B	F-actin capping protein, beta subunit	Family	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR037282 all species →	Homologous_superfamily	F-actin-capping protein subunit alpha/beta	Interproscan
IPR001698 all species →	Family	F-actin-capping protein subunit beta	Interproscan
IPR019771 all species →	Conserved_site	F-actin capping protein, beta subunit, conserved site	Interproscan
IPR043175 all species →	Homologous_superfamily	F-actin-capping protein subunit beta, N-terminal domain	Interproscan
IPR042276 all species →	Homologous_superfamily	F-actin-capping protein subunit alpha/beta, domain 2	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR10619 all species →	F-ACTIN-CAPPING PROTEIN SUBUNIT BETA	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0008290 all species →	Cellular Component	F-actin capping protein complex	Interproscan
GO:0051016 all species →	Biological Process	barbed-end actin filament capping	Interproscan
GO:0003779 all species →	Molecular Function	actin binding	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0030036 all species →	Biological Process	actin cytoskeleton organization	Interproscan
GO:0000902 all species →	Biological Process	cell morphogenesis	Interproscan
GO:0010591 all species →	Biological Process	regulation of lamellipodium assembly	Interproscan
GO:0051015 all species →	Molecular Function	actin filament binding	Interproscan
GO:0051490 all species →	Biological Process	negative regulation of filopodium assembly	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10365	CAPZB; F-actin-capping protein subunit beta	-	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068700545.1 across 36 RNA-seq samples of Montipora foliosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples

30TPM > 0

1Conditions

713.6Max TPM

383.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
Polyps	36	30	383.13	713.63

Per sample · hover a bar for the full sample record

Show the sample table (36 samples)

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR27940180	Polyps	Polyps	not recorded	not recorded	SRP199550	713.63
SRR12904780	Polyps	Polyps	not recorded	not recorded	SRP199550	711.27
SRR12904792	Polyps	Polyps	not recorded	not recorded	SRP199550	562.99
SRR27940179	Polyps	Polyps	not recorded	not recorded	SRP199550	562.71
SRR27940177	Polyps	Polyps	not recorded	not recorded	SRP199550	558.21
SRR12904791	Polyps	Polyps	not recorded	not recorded	SRP199550	557.99
SRR12710854	Polyps	Polyps	OA4 day9	not recorded	SRP199550	524.18
SRR12959211	Polyps	Polyps	E4 day9	not recorded	SRP199550	518.22
SRR12959212	Polyps	Polyps	E4 day9	not recorded	SRP199550	504.67
SRR12959226	Polyps	Polyps	E4 day3	not recorded	SRP199550	504.12
SRR12786903	Polyps	Polyps	OA4 day0	not recorded	SRP199550	492.57
SRR12959181	Polyps	Polyps	E4 day0	not recorded	SRP199550	474.95
SRR12959199	Polyps	Polyps	E4 day15	not recorded	SRP199550	471.28
SRR12959238	Polyps	Polyps	E4 day0	not recorded	SRP199550	470.26
SRR12959213	Polyps	Polyps	E4 day9	not recorded	SRP199550	463.96
SRR12959198	Polyps	Polyps	E4 day15	not recorded	SRP199550	463.72
SRR12959237	Polyps	Polyps	E4 day0	not recorded	SRP199550	442.82
SRR12959224	Polyps	Polyps	E4 day3	not recorded	SRP199550	440.92
SRR12959225	Polyps	Polyps	E4 day3	not recorded	SRP199550	438.22
SRR12959200	Polyps	Polyps	E4 day15	not recorded	SRP199550	437.53
SRR12710865	Polyps	Polyps	OA4 day3	not recorded	SRP199550	424.58
SRR12710866	Polyps	Polyps	OA4 day3	not recorded	SRP199550	422.45
SRR12710845	Polyps	Polyps	OA4 day3	not recorded	SRP199550	417.83
SRR12710852	Polyps	Polyps	OA4 day9	not recorded	SRP199550	409.85
SRR12710853	Polyps	Polyps	OA4 day9	not recorded	SRP199550	404.32
SRR12786895	Polyps	Polyps	OA4 day0	not recorded	SRP199550	399.41
SRR12786904	Polyps	Polyps	OA4 day0	not recorded	SRP199550	390.20
SRR12959187	Polyps	Polyps	E4 day21	not recorded	SRP199550	232.09
SRR12959185	Polyps	Polyps	E4 day21	not recorded	SRP199550	197.33
SRR12959186	Polyps	Polyps	E4 day21	not recorded	SRP199550	180.46
SRR12807380	Polyps	Polyps	OA4 day0	not recorded	SRP199550	0.00
SRR12849112	Polyps	Polyps	OA4 day0	not recorded	SRP199550	0.00
SRR12927879	Polyps	Polyps	E4 day0	not recorded	SRP199550	0.00
SRR12963483	Polyps	Polyps	E4 day0	not recorded	SRP199550	0.00
SRR9129315	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00
SRR9613518	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00

Source: CnidoSite RNA-seq expression matrices (MFOLI_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora foliosa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

Direction	Partners	Most correlated partner	PCC
Positively correlated	31	XP_068692262.1	0.96774068298288
Negatively correlated	4	XP_068681185.1	-0.532447518963862

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora foliosa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

Analysis	What it does	Status
Primer design	Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.	template found	open →
BLAST	Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.	template found	open →
Expression heatmap	Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.	ready	open →
Gene family / orthogroup	Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.		open →
Gene set analysis	Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.		open →