Genomic Location: chr6:23754990...23841191
NR annotation: XP_029203867.2, fibrocystin-L-like isoform X1 [Acropora millepora]
Species Montipora foliosa · all data for this species · gene families
| CDS |
| LOC138007013 |
| Transcript |
| rna-XM_068853679.1 |
| Protein |
| XP_068709780.1 |
| UniProt accession | Description |
|---|---|
| Q86WI1 | Fibrocystin-L OS=Homo sapiens OX=9606 GN=PKHD1L1 PE=1 SV=2 |
| Q80ZA4 | Fibrocystin-L OS=Mus musculus OX=10090 GN=Pkhd1l1 PE=1 SV=1 |
| E2RK30 | Fibrocystin OS=Canis lupus familiaris OX=9615 GN=PKHD1 PE=3 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001210 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF01833 all species → | TIG | IPT/TIG domain | Domain | Interproscan |
| PF01753 all species → | zf-MYND | MYND finger | Domain | Interproscan |
| PF07691 all species → | PA14 | PA14 domain | Domain | Interproscan |
| PF10162 all species → | G8 | G8 domain | Domain | Interproscan |
| PF00028 all species → | Cadherin | Cadherin domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR002126 all species → | Domain | Cadherin-like | Interproscan |
| IPR019316 all species → | Domain | G8 domain | Interproscan |
| IPR013783 all species → | Homologous_superfamily | Immunoglobulin-like fold | Interproscan |
| IPR015919 all species → | Homologous_superfamily | Cadherin-like superfamily | Interproscan |
| IPR014756 all species → | Homologous_superfamily | Immunoglobulin E-set | Interproscan |
| IPR037524 all species → | Domain | PA14/GLEYA domain | Interproscan |
| IPR002909 all species → | Domain | IPT domain | Interproscan |
| IPR002893 all species → | Domain | Zinc finger, MYND-type | Interproscan |
| IPR008972 all species → | Homologous_superfamily | Cupredoxin | Interproscan |
| IPR006626 all species → | Repeat | Parallel beta-helix repeat | Interproscan |
| IPR020894 all species → | Conserved_site | Cadherin conserved site | Interproscan |
| IPR011050 all species → | Homologous_superfamily | Pectin lyase fold/virulence factor | Interproscan |
| IPR011658 all species → | Domain | PA14 domain | Interproscan |
| IPR012334 all species → | Homologous_superfamily | Pectin lyase fold | Interproscan |
| IPR052387 all species → | Family | Fibrocystin-related protein | Interproscan |
| IPR036439 all species → | Homologous_superfamily | Dockerin domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46769 all species → | POLYCYSTIC KIDNEY AND HEPATIC DISEASE 1 (AUTOSOMAL RECESSIVE)-LIKE 1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005509 all species → | Molecular Function | calcium ion binding | Interproscan |
| GO:0007156 all species → | Biological Process | homophilic cell adhesion via plasma membrane adhesion molecules | Interproscan |
| GO:0016020 all species → | Cellular Component | membrane | Interproscan |
| GO:0005886 all species → | Cellular Component | plasma membrane | Interproscan |
| GO:0007155 all species → | Biological Process | cell adhesion | Interproscan |
| GO:0000272 all species → | Biological Process | polysaccharide catabolic process | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K27624 | PKHD1L1; fibrocystin-L | - | Cilium and associated proteins | ko03037 | deepkoala |
Transcript abundance of XP_068709780.1 across 36 RNA-seq samples of Montipora foliosa. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 36 | 29 | 3.30 | 14.82 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR12710853 | Polyps | Polyps | OA4 day9 | not recorded | SRP199550 | 14.82 |
| SRR12710852 | Polyps | Polyps | OA4 day9 | not recorded | SRP199550 | 13.86 |
| SRR12710854 | Polyps | Polyps | OA4 day9 | not recorded | SRP199550 | 10.88 |
| SRR12959198 | Polyps | Polyps | E4 day15 | not recorded | SRP199550 | 10.45 |
| SRR12959199 | Polyps | Polyps | E4 day15 | not recorded | SRP199550 | 8.96 |
| SRR12959200 | Polyps | Polyps | E4 day15 | not recorded | SRP199550 | 8.91 |
| SRR12959211 | Polyps | Polyps | E4 day9 | not recorded | SRP199550 | 6.07 |
| SRR12959213 | Polyps | Polyps | E4 day9 | not recorded | SRP199550 | 3.98 |
| SRR12959212 | Polyps | Polyps | E4 day9 | not recorded | SRP199550 | 3.78 |
| SRR12959238 | Polyps | Polyps | E4 day0 | not recorded | SRP199550 | 3.38 |
| SRR12959226 | Polyps | Polyps | E4 day3 | not recorded | SRP199550 | 3.21 |
| SRR12959237 | Polyps | Polyps | E4 day0 | not recorded | SRP199550 | 2.94 |
| SRR12959181 | Polyps | Polyps | E4 day0 | not recorded | SRP199550 | 2.92 |
| SRR12959225 | Polyps | Polyps | E4 day3 | not recorded | SRP199550 | 2.86 |
| SRR12959224 | Polyps | Polyps | E4 day3 | not recorded | SRP199550 | 2.84 |
| SRR12710866 | Polyps | Polyps | OA4 day3 | not recorded | SRP199550 | 2.20 |
| SRR12710865 | Polyps | Polyps | OA4 day3 | not recorded | SRP199550 | 1.67 |
| SRR12904780 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 1.63 |
| SRR27940180 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 1.63 |
| SRR12959187 | Polyps | Polyps | E4 day21 | not recorded | SRP199550 | 1.60 |
| SRR12959186 | Polyps | Polyps | E4 day21 | not recorded | SRP199550 | 1.40 |
| SRR12710845 | Polyps | Polyps | OA4 day3 | not recorded | SRP199550 | 1.39 |
| SRR12959185 | Polyps | Polyps | E4 day21 | not recorded | SRP199550 | 1.35 |
| SRR12786904 | Polyps | Polyps | OA4 day0 | not recorded | SRP199550 | 1.29 |
| SRR12786895 | Polyps | Polyps | OA4 day0 | not recorded | SRP199550 | 1.02 |
| SRR12904791 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 1.00 |
| SRR27940177 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 1.00 |
| SRR12904792 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.94 |
| SRR27940179 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.93 |
| SRR12786903 | Polyps | Polyps | OA4 day0 | not recorded | SRP199550 | 0.00 |
| SRR12807380 | Polyps | Polyps | OA4 day0 | not recorded | SRP199550 | 0.00 |
| SRR12849112 | Polyps | Polyps | OA4 day0 | not recorded | SRP199550 | 0.00 |
| SRR12927879 | Polyps | Polyps | E4 day0 | not recorded | SRP199550 | 0.00 |
| SRR12963483 | Polyps | Polyps | E4 day0 | not recorded | SRP199550 | 0.00 |
| SRR9129315 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613518 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (MFOLI_TPM,
StringTie quantification over 36 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora foliosa tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 26 | XP_068702920.1 | 0.982282066657932 |
| Negatively correlated | 5 | XP_068700459.1 | -0.402511817212341 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora foliosa, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |