Genomic Location: chr9:5932768...6011451
NR annotation: XP_029204738.2, LOW QUALITY PROTEIN: ubiquitin-like modifier-activating enzyme 1 [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families
| CDS |
| LOC138015187 |
| Transcript |
| rna-XM_068862140.1 |
| Protein |
| XP_068718241.1 |
| UniProt accession | Description |
|---|---|
| Q29504 | Ubiquitin-like modifier-activating enzyme 1 OS=Oryctolagus cuniculus OX=9986 GN=UBA1 PE=1 SV=1 |
| A3KMV5 | Ubiquitin-like modifier-activating enzyme 1 OS=Bos taurus OX=9913 GN=UBA1 PE=2 SV=1 |
| Q5U300 | Ubiquitin-like modifier-activating enzyme 1 OS=Rattus norvegicus OX=10116 GN=Uba1 PE=1 SV=1 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0001418 (this species only) · gene tree & orthology |
| Ubiquitin family | E1|ThiF|ThiF · all ubiquitin genes in this species |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00899 all species → | ThiF | ThiF family | Domain | Interproscan |
| PF16190 all species → | E1_FCCH | Ubiquitin-activating enzyme E1 FCCH domain | Domain | Interproscan |
| PF09358 all species → | E1_UFD | Ubiquitin fold domain | Domain | Interproscan |
| PF16191 all species → | E1_4HB | Ubiquitin-activating enzyme E1 four-helix bundle | Domain | Interproscan |
| PF10585 all species → | UBA_E1_SCCH | Ubiquitin-activating enzyme, SCCH domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR033127 all species → | Active_site | Ubiquitin-activating enzyme E1, Cys active site | Interproscan |
| IPR018965 all species → | Domain | Ubiquitin-activating enzyme E1, C-terminal | Interproscan |
| IPR000594 all species → | Domain | THIF-type NAD/FAD binding fold | Interproscan |
| IPR000011 all species → | Family | Ubiquitin/SUMO-activating enzyme E1-like | Interproscan |
| IPR032418 all species → | Domain | Ubiquitin-activating enzyme E1, FCCH domain | Interproscan |
| IPR042449 all species → | Homologous_superfamily | Ubiquitin-activating enzyme E1, inactive adenylation domain, subdomain 1 | Interproscan |
| IPR035985 all species → | Homologous_superfamily | Ubiquitin-activating enzyme | Interproscan |
| IPR032420 all species → | Domain | Ubiquitin-activating enzyme E1, four-helix bundle | Interproscan |
| IPR038252 all species → | Homologous_superfamily | Ubiquitin-activating enzyme E1, C-terminal domain superfamily | Interproscan |
| IPR045886 all species → | Family | ThiF/MoeB/HesA family | Interproscan |
| IPR018075 all species → | Family | Ubiquitin-activating enzyme E1 | Interproscan |
| IPR042063 all species → | Homologous_superfamily | Ubiquitin-activating enzyme E1, SCCH domain | Interproscan |
| IPR042302 all species → | Homologous_superfamily | Ubiquitin-activating enzyme E1, FCCH domain superfamily | Interproscan |
| IPR018074 all species → | Conserved_site | Ubiquitin-activating enzyme E1, conserved site | Interproscan |
| IPR019572 all species → | Domain | Ubiquitin-activating enzyme, SCCH domain | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR10953 all species → | UBIQUITIN-ACTIVATING ENZYME E1 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0008641 all species → | Molecular Function | ubiquitin-like modifier activating enzyme activity | Interproscan |
| GO:0036211 all species → | Biological Process | protein modification process | Interproscan |
| GO:0004839 all species → | Molecular Function | ubiquitin activating enzyme activity | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0005737 all species → | Cellular Component | cytoplasm | Interproscan |
| GO:0006511 all species → | Biological Process | ubiquitin-dependent protein catabolic process | Interproscan |
| GO:0006974 all species → | Biological Process | DNA damage response | Interproscan |
| GO:0016567 all species → | Biological Process | protein ubiquitination | Interproscan |
| GO:0032446 all species → | Biological Process | protein modification by small protein conjugation | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K03178 | UBE1, UBA1; ubiquitin-activating enzyme E1 | EC:6.2.1.45 | Exosome | ko04147 | deepkoala |
Transcript abundance of XP_068718241.1 across 36 RNA-seq samples of Montipora capricornis. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 36 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR12710846 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710847 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710848 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710855 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12710857 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12710858 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12786896 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12786897 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12786898 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12807381 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12849113 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12904781 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12904782 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12904783 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12927880 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959182 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959183 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959184 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959188 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959189 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959190 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959201 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959202 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959203 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959214 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959215 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959216 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959227 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959229 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959230 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12963484 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR27940191 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940192 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940193 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9129316 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613519 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM,
StringTie quantification over 36 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Montipora capricornis network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
