Detailed information of XP_068721632.1 in Montipora capricornis

Genomic Location: chr10:51037781...51087216
NR annotation: KAJ7376475.1, acyl-CoA synthetase medium-chain member 4 [Desmophyllum pertusum]
Species Montipora capricornis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P0C7M7Acyl-coenzyme A synthetase ACSM4, mitochondrial OS=Homo sapiens OX=9606 GN=ACSM4 PE=1 SV=1
Q3UNX5Acyl-coenzyme A synthetase ACSM3, mitochondrial OS=Mus musculus OX=10090 GN=Acsm3 PE=1 SV=2
Q6SKG1Acyl-coenzyme A synthetase ACSM3, mitochondrial OS=Rattus norvegicus OX=10116 GN=Acsm3 PE=2 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001421 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF13193
all species →		AMP-binding_CAMP-binding enzyme C-terminal domainDomainInterproscan
PF00501
all species →		AMP-bindingAMP-binding enzymeFamilyInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR025110
all species →		DomainAMP-binding enzyme, C-terminal domainInterproscan
IPR000873
all species →		DomainAMP-dependent synthetase/ligase domainInterproscan
IPR020845
all species →		Conserved_siteAMP-binding, conserved siteInterproscan
IPR042099
all species →		Homologous_superfamilyANL, N-terminal domainInterproscan
IPR045851
all species →		Homologous_superfamilyAMP-binding enzyme, C-terminal domain superfamilyInterproscan
IPR051087
all species →		FamilyMitochondrial Acyl-CoA Synthetase Medium-ChainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR43605
all species →		ACYL-COENZYME A SYNTHETASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004321
all species →		Molecular Functionfatty-acyl-CoA synthase activityInterproscan
GO:0005759
all species →		Cellular Componentmitochondrial matrixInterproscan
GO:0006633
all species →		Biological Processfatty acid biosynthetic processInterproscan
GO:0006637
all species →		Biological Processacyl-CoA metabolic processInterproscan
GO:0015645
all species →		Molecular Functionfatty acid ligase activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01896ACSM; medium-chain acyl-CoA synthetaseEC:6.2.1.2
Lipid biosynthesis proteinsko01004deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068721632.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples
30TPM > 0
1Conditions
61.6Max TPM
21.5Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Polyps 36 30 21.46 61.57

Per sample · hover a bar for the full sample record

Show the sample table (36 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR27940191 Polyps Polyps not recorded not recorded SRP199550 61.57
SRR12904783 Polyps Polyps not recorded not recorded SRP199550 61.56
SRR12904781 Polyps Polyps not recorded not recorded SRP199550 45.18
SRR27940193 Polyps Polyps not recorded not recorded SRP199550 40.55
SRR12904782 Polyps Polyps not recorded not recorded SRP199550 38.06
SRR27940192 Polyps Polyps not recorded not recorded SRP199550 37.80
SRR12786896 Polyps Polyps OA3 day0 not recorded SRP199550 37.51
SRR12786897 Polyps Polyps OA3 day0 not recorded SRP199550 36.99
SRR12786898 Polyps Polyps OA3 day0 not recorded SRP199550 35.50
SRR12959229 Polyps Polyps E3 day3 not recorded SRP199550 31.78
SRR12959216 Polyps Polyps E3 day9 not recorded SRP199550 26.62
SRR12959215 Polyps Polyps E3 day9 not recorded SRP199550 26.55
SRR12959214 Polyps Polyps E3 day9 not recorded SRP199550 24.48
SRR12959227 Polyps Polyps E3 day3 not recorded SRP199550 23.15
SRR12710846 Polyps Polyps OA3 day3 not recorded SRP199550 21.23
SRR12710848 Polyps Polyps OA3 day3 not recorded SRP199550 20.64
SRR12959182 Polyps Polyps E3 day0 not recorded SRP199550 20.37
SRR12959183 Polyps Polyps E3 day0 not recorded SRP199550 19.96
SRR12959184 Polyps Polyps E3 day0 not recorded SRP199550 19.74
SRR12710847 Polyps Polyps OA3 day3 not recorded SRP199550 19.66
SRR12959202 Polyps Polyps E3 day15 not recorded SRP199550 15.54
SRR12959203 Polyps Polyps E3 day15 not recorded SRP199550 14.36
SRR12959201 Polyps Polyps E3 day15 not recorded SRP199550 13.96
SRR12959188 Polyps Polyps E3 day21 not recorded SRP199550 12.67
SRR12959230 Polyps Polyps E3 day3 not recorded SRP199550 12.63
SRR12959189 Polyps Polyps E3 day21 not recorded SRP199550 12.32
SRR12959190 Polyps Polyps E3 day21 not recorded SRP199550 11.38
SRR12710857 Polyps Polyps OA3 day9 not recorded SRP199550 11.05
SRR12710858 Polyps Polyps OA3 day9 not recorded SRP199550 10.23
SRR12710855 Polyps Polyps OA3 day9 not recorded SRP199550 9.51
SRR12807381 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12849113 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12927880 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12963484 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR9129316 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613519 Polyps Polyps not recorded not recorded SRP199550 0.00

Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated25XP_068721576.10.967861359200611
Negatively correlated3XP_068724527.1-0.400506281357706

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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