Gene detail

Detailed information of XP_068726595.1 in Montipora capricornis

Genomic Location: chr2:44532438...44550612
NR annotation: XP_022808249.1, folliculin-like [Stylophora pistillata]
Species Montipora capricornis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_068870494.1

GCGAACGTTGCTTCTCATATGACTGTCATGACTTCACTTCGGGGTGCTCGGGATTTTTAAAGAATCGTTCTCAAGGGAAAGTACTTAGCTGGGCTCCCAAGGAAAGAAGCACCatgaaaacattgaaattgcTTCGTCAAGATGACgagacaaaattaatttggtTGCCCTAAGCTACAAGGGGTGGTATGTTTTGGTCTGATCTGAGCGTTCGAGACCGTCTGATCGTCCTAAAATGAATGCTATAATAGCGTTGTGCCACTTTTGTGAATTCCACGgacccagtgttttgttttgtacacagGCCTTTCACTGTGAGGCTCATGATCCCCTAAAGGAGGCTTGTACATCAGCATCCGAGTGTGGTGCATGTATAAAAAGAAATTCCACCCATTTTGCTTCAGATACCCAAGAATCCAGTTCATCGTGTGATTCCTGGGCATCATCAAGACCAACACAATGTGAGGCCTGTAAGTCACTGGACCATACCCATGCAGGATACATCAGTATTGACCGTGAGGCCCACATCAGTTACTATAGTAACAGGTCTCCTGAGCAACCAGAATTGTACAGTGTGGTAAGACAGGCCTGTGTGAGAAGTCTGAGCTGTGAGGTGTGCCCTGGCAGAGAGGGGCCAATGTTCTTTGGTGAAGAAACATCTGGTTATGTATTCACTCACACATTCTTCTTAAAGGATGCTCAATCCAGAGGATTCCAGAGATGGTACAGCATAATAGCTGTGATGAAAGACCGTATTTACCTGGTGAATTCCTGGCCATTCTTAGTAAGCCATTTTAGAGAACTGATCGATGATCTACAAGCTAAGGCAACTGCTGTGTATGATGCTGAGCATGCTGTGAGCGTCCAGAAAGGTCAACACATTCAGCCCAGTACAAATGGATACCTGTTTGCTCCTGGAATGGCACCTGATATTTTCAGAAGACAGCGAGGAGGAAACAAAACATACAGAGGGATTGCAGACTTGCTTGGAGACAAGGATCTGTTTGCTAGCCTTCATCAAAGGTTTTCTTGGATGTTGAAAGCATGTGGTAACCGAGTCACAGAAAAACTTCTTGAGGGACCACCAAAGGAAGAACTCTTCACAGATCTGGAAATGCAGAGAGAAGACCACCTCCAAGATACCAATACTAACAGCCAAGAAGGTGAAGTGAGCGGACCAATTTTCACATCCCTTCGACACATTTTAAAGGTCCTTGGGAGTCACAAGTTTCACTTGCTAGCATTTCATGTCATTCAGGGGAATCAAGTAATTGTACGAGGCAAAAACCAAAAGACTGTGGAGTCAATCCTCGATTGTCTCAAgGTTCTTATACCAAGTGGTTGCTGTTCTTGTGTCCCATACAGTACCGAGTACAAGGATTCCTGGCAGTGCAACTTTCTTGGTTTGGTTCCTTCAGTGGAAATTCCTCCGCATGTGTTGTCCTCTGacctttttgttcttcttgatGTCATTTCTCCACCGGAGCATGCTTCTGAGTATTCTATTGGTGAACAGCTGAGTGAACCAGACGACTTTCAAGGTTACGGTTTCGTTGTTTGTGGAAAAGAGAACACTACAGATCCCTCCATTCTGCAGAAAATTGAGGAAGGTCTTGAGAATGCCAATCTCTCTGATGCAGTGTTTGATCAGTTGCTAGTATGTCTTAAGGAGGAGTGGATGGACAAGGTCAAGGTGATTTTTAAATTTGCCCGCTCAGGCCCCAGCACAAGTGAAGATAAAGAAAAGCTGCTTCGAATTTTAGGCGCCAAGCCTGAAGATGAGATTGTTCTCAAGTTTTGGATGACGGGACTCAACAAACAGTATCGATCTCATCTTCTGACCTGTAGTAGCACGGGCTCATCCTCTTGACGAAGAGAGCGTCATTCGTTTCGGCGTTTCTCTGCAACGTTTCACCTTGGGTTCTGTTTGGAATTAAGTAGAAAGTTTCGGGTATTTGAACTCGCTGCTCAAAGTTGAAAtgaattgttttattacagTACTTTGATTACAGTGTCCAAAATGGGTCATGATTGCGATGATTGCTGTCGAGGTCTTTCAAAACAAGTGCAAAGGTCGACGTCAGCTCCGCTTGTGTCATTGCTTTACCTAATGCTTTGCAAGATCAATGGGTCAGTGTCGATTCAAGAGCATCCCGGCTCCGAAATCCCTCAAAAATTTTGATGACAGCGATTTCTGGAGAgttagcccttttcacggttagtttttctcatttgcattacaatgtaatctaacgtggatgtgaggcaatttcgggttaaaactacaaaatagcccgaaattgcctcacatacatgctagattacattgtaatgcaaatgagaaaaactaaccgtgaaaagggatATTAGGCAGGTTACGTGGTATGGCATACCGCGTATGGCATTCTATGTTCATGTTTTGCGTTGTGCCGACTCAAATCTCCATCATTTATTTATGCAGTGCTTTCACACAGTTCAAGTTATGGCCATTTCAACAagggttttaaaaaaaacacctgtAATTGTCGGCGGTTTAATCAGCGATTGTGCCGGGCAAGCCCCAAACGCCGTTTGTTTTCGCAAAAGCCAACATTCATGAGACACAAACGGTTCTTTTTTTGGCTATCCGGCAAGCACCGGTTTAATTACATCGCTCAAAAAGACAGCAGACAACGTAAGACTTGTTAAACCGACCCACCATCATCAAGAAGTTTCTTTTACTGGATAGAAAGCAAAGATTTCTCCTCATAGAACAGAAATGGTGTTTCTGAGCTCAACATTGTGTGTATGTGTGATGCTCCGCTGAGAAAGGTTATCAGTGAGTTTCTTTGAGTTCTTCAGATGAGTACCTGCAATAAATGCCTGGCGGTTATGACCGATGGATTCACTTACCAAGATGATTTGTTTCGATTCGACTCTCGCTCTTTTCATTGAATCTCGAAGCGTAAAGGAGATCTTGCGCGGCGATGGAAACTAGATAAGAGCTTACTGCTTAAAACATGATACAATGTAAATTCTTGCCCCATAAGCAGTTCACGTGTTTAATAAACAGACGACAAGGTA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8NFG4	Folliculin OS=Homo sapiens OX=9606 GN=FLCN PE=1 SV=1
Q3B7L5	Folliculin OS=Bos taurus OX=9913 GN=FLCN PE=2 SV=1
Q5M7Q1	Folliculin OS=Xenopus tropicalis OX=8364 GN=flcn PE=2 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0005183 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF11704 all species →	Folliculin	Vesicle coat protein involved in Golgi to plasma membrane transport	Family	Interproscan
PF16692 all species →	Folliculin_C	Folliculin C-terminal domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR044886 all species →	Homologous_superfamily	Folliculin, DENN domain, C-terminal superfamily	Interproscan
IPR037520 all species →	Domain	Folliculin/SMCR8, longin domain	Interproscan
IPR037521 all species →	Domain	Folliculin/SMCR8, tripartite DENN domain	Interproscan
IPR032035 all species →	Domain	Folliculin, DENN domain	Interproscan
IPR021713 all species →	Family	Folliculin	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR31441 all species →	FOLLICULIN FAMILY MEMBER	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005096 all species →	Molecular Function	GTPase activator activity	Interproscan
GO:0000122 all species →	Biological Process	negative regulation of transcription by RNA polymerase II	Interproscan
GO:0005829 all species →	Cellular Component	cytosol	Interproscan
GO:0030511 all species →	Biological Process	positive regulation of transforming growth factor beta receptor signaling pathway	Interproscan
GO:1904263 all species →	Biological Process	positive regulation of TORC1 signaling	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K09594	FLCN, BHD; folliculin	-	Renal cell carcinoma	ko05211	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.