Gene detail

Detailed information of XP_068734432.1 in Montipora capricornis

Genomic Location: chr2:61858106...61919086
NR annotation: XP_015758666.1, PREDICTED: tyrosine-protein kinase CSK-like isoform X1 [Acropora digitifera]
Species Montipora capricornis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_068878331.1

TTTCCTGTGGGAATACAACCCAAGTAAGCTGCGGAAGTCGTGGGTCTACAGTTGCTGGGCGAAAGGTTGAGGGCCTCTATATTTTCCATACAGGCTTCTAAAAACTTTTCACTGTTAAACGCTGTTGCTCCTGGCAAACGAAGGCCTCTAGGGTAGGCAGCAATAAGGGGCAAATGCCTCATCATGTCTGGGAACAACTGTGAACAGCTTAAACCATGGCCACATGGTACTGCAGTTGTCGGAAAGTATGAATTCAAAGGAAGGACACCAGAGGATCTGCCATTCAAGAAGGATGAGCTGTTATATATTGAATGTGTCACTCGGGATCCTCATTGGTACAGGGCAAAAAATACCAAAGGAAAAAAGGGAATGATTCCTTACAACTACGTGAAAGAGTTGGATCAAAAGGGAGCTGTCAAACTTCATGCAATGCCATGGTTTCATGGTAAAATAACAAGAGAAAAGGCAGAAGAACTCCTTAATCCTTATGAGGAGGGTTTGTTTCTTGTAAGAGAGAGCCACAATTACCAGGGAGACTATACTCTTTCAGTTTGCTTTGATTCCAAGGTAGATCATTATAGAGTGCGGTATACACctgacaataaacttacagTTGATGATGAAGTATTTTTTGAAAATCTCACAAAACTTGTACAGTATTACGAGAGAGATGCAGATGGACTTTCAACAAGACTTGCAAAACCTTTAGAGAAAAAAGGGGGCAAATTTGCCTTTTCAGTTGATCCAGAGTCATTTAGGAAAGAGGGATGGACAATAATGCGCAGTGAGCTAAAGCTTGGCACTTCCATTGGCAAGGGAGAGTTTGGAGATGTTCTTCAAGGCATATACAAAGGGCAGAAGGTTGCTGTGAAATCACTTTTGGATGACAGCCATGCAGCGCAATCATTCCTTGCAGAGGCTTCAGTTATGACGAATTTGAGCCATAAGAATCTTGTGAAACTGCTTGGTGTGTCACTGGATGGAAATCCTATTTATATTGTGACAGAATTTTGTGGAAAGGGCAGCTTAGTTGAGTACTTGAGAACAAGAGGAAGAACAGTGATAGGACAGAAAGATCTTATAGGATTTGCCAGGGATGTTGCTGCGGGTATGCAGTACTTAGAATCAAAGCTTTTAGTGCACAGGGACTTGGCTGCAAGGAATGTACTTGTGCATGATGACGGTACAGCGAAGGTGTCAGATTTTGGACTAGCAAGGGGAGCTGATTTTAATTTAGAAGGTGGAAAATTTCCTATCAAATGGACAGCTCCTGAGGCCATCAAACAGGGGCAATTTTCAACCCAATCAGATGTATGGAGTTACGGTGTGTTGTTGTGGGAACTTTTTTCATTTGGGAGAACACCATATCCTCGAGTGCACATCGACAGTGTGATGGAGACGATTGAGAGAGGTTATCGCATGGAATGTCCTGATGGATGCCCACAGAAAATTTACTGTGTCATGCGGAATTGCTGGGAAATAAACCCAAAACAACGACCATCATTTGAGAAAATATATGCAGTATTAGATGATATTTATAGATCATTTGTGCCGGGTAACAAATTTGAATGAGTATTTTGGCTTCTAAGCTGTAAATTGTGTATTAAATAGGAGACTGgtttcaataataattactcTATTATCGTTCCCTTCTTGCAAAATTAATATCAGCAGTCTCAGCTCTTGAATGAATTCAGTGGCTTGCACAGCGACTATATCCTATCGCTTTATTTTATTGGCTTCAGTGTGGTCATCTCCTTTTGTTCGTTTAAATCAGTCGTGGTAAATGGAAAtcatatatattaaaaattGTAACCAGTTAAGAAAGAAACTCGTACAGCTGTAGGTGTAGTAATGTTGTTTCTAATTCCTAAGTAGAATAAGGAGGCAATCAACTTTTATATTTATGTGATGAGTTTGTtactatttttgttttaaatatttgaGGACTGTAGCCCAATATATTTCCTTTCATGGTATCTTTGCATAGGTTACAAGACCGTTTTAGAGTAAAGCAGGcctgattttgtaatttttaattGAAAATAGTGCTGTGTTTGAAGCAACGGCTAACTTCATTCAAATTATGTTCAGGTGCAAGTTACAACACATGTACATATTAGCGTAAAGAACTCGGGTTAACGCCTCCGTGTCCTTCCCAGCACTTCGAATGTGAGTGTAAAACACGAGATTTAATGAGGCCATGCTAATGTAGGTTTCTGAAGTCAACACACGATGCATACCTGGATCACTTTAGTAGTGTTATGTTACAGGTAAAGCAAATTATGGAAGGGCTGCTTTGCAGATTCCTTGTTCTTGATGGTAGTCTCGACGTAGCAGGTAATTGTAATTTATAGCAAATCAAAACACACTTGGTAAGACTGAAAGGAATCCTCGCTTTCTCATCGAAGACAATTAGTGACACACAAAAGGTCATTAGACTGTTCATCGCACGGAAGTGTTACATTGTAccggggacagctattcttagagttattttcatagagttatgtcgtagagttagagttaagtttccaaaatcctgaattcacgattttggactgccaaaatcctgaattcacgattttggaattcaagattttggactaccaaaatcttgaattccaaaatcgtgaattcaggattttggcagtccaaaatcttgaattcaggattttcgcagtcgttaactctaactctaagtcataactactgaaataactctattgatagttaacctctaTTGTACCTTTACAAAGCAGTTTAATTAATAACTCGTTGCTTGGAATTTTTTCAGTTCAACCAAAGCGACCGCTTTTCtatgttttcacatgacgtcacgaccgccatgttggtgccctaaacaaagaaaaggcggcctccgggaatttaactctattattatgcaaacgcttccttttgttttctttgaaaaacatggctgttgatcacgtgagtgaaaaccagcaatatttTTGTTGTGGCATGTTGTTGAACAATAGGCTTTTTACAGTAACAATGAGTGTTCAATACAACacacataattatttttttagttgTTATGTCCGGTTTGGGTTAACCTGAAAAAATCATAGTTTTGAAATGGAAAA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
P41240	Tyrosine-protein kinase CSK OS=Homo sapiens OX=9606 GN=CSK PE=1 SV=1
Q0VBZ0	Tyrosine-protein kinase CSK OS=Bos taurus OX=9913 GN=CSK PE=2 SV=1
P32577	Tyrosine-protein kinase CSK OS=Rattus norvegicus OX=10116 GN=Csk PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000425 (this species only) · gene tree & orthology
Ubiquitin family	UBD\|Other\|SH3 · all ubiquitin genes in this species

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF07714 all species →	PK_Tyr_Ser-Thr	Protein tyrosine and serine/threonine kinase	Domain	Interproscan
PF00018 all species →	SH3_1	SH3 domain	Domain	Interproscan
PF00017 all species →	SH2	SH2 domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR036860 all species →	Homologous_superfamily	SH2 domain superfamily	Interproscan
IPR035027 all species →	Domain	CSK-like, SH2 domain	Interproscan
IPR001452 all species →	Domain	SH3 domain	Interproscan
IPR020635 all species →	Domain	Tyrosine-protein kinase, catalytic domain	Interproscan
IPR017441 all species →	Binding_site	Protein kinase, ATP binding site	Interproscan
IPR008266 all species →	Active_site	Tyrosine-protein kinase, active site	Interproscan
IPR050198 all species →	Family	Non-receptor tyrosine kinases involved in cell signaling	Interproscan
IPR001245 all species →	Domain	Serine-threonine/tyrosine-protein kinase, catalytic domain	Interproscan
IPR000980 all species →	Domain	SH2 domain	Interproscan
IPR036028 all species →	Homologous_superfamily	SH3-like domain superfamily	Interproscan
IPR011009 all species →	Homologous_superfamily	Protein kinase-like domain superfamily	Interproscan
IPR000719 all species →	Domain	Protein kinase domain	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR24418 all species →	TYROSINE-PROTEIN KINASE	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0005515 all species →	Molecular Function	protein binding	Interproscan
GO:0004713 all species →	Molecular Function	protein tyrosine kinase activity	Interproscan
GO:0006468 all species →	Biological Process	protein phosphorylation	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0004672 all species →	Molecular Function	protein kinase activity	Interproscan
GO:0004715 all species →	Molecular Function	non-membrane spanning protein tyrosine kinase activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K05728	CSK; c-src tyrosine kinase	EC:2.7.10.2	Exosome	ko04147	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068734432.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples

30TPM > 0

1Conditions

93.4Max TPM

48.9Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
Polyps	36	30	48.87	93.43

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR27940191	Polyps	Polyps	not recorded	not recorded	SRP199550	93.43
SRR12786898	Polyps	Polyps	OA3 day0	not recorded	SRP199550	93.32
SRR12904783	Polyps	Polyps	not recorded	not recorded	SRP199550	92.92
SRR12959227	Polyps	Polyps	E3 day3	not recorded	SRP199550	91.67
SRR12786896	Polyps	Polyps	OA3 day0	not recorded	SRP199550	88.00
SRR12786897	Polyps	Polyps	OA3 day0	not recorded	SRP199550	86.74
SRR12959229	Polyps	Polyps	E3 day3	not recorded	SRP199550	69.10
SRR27940193	Polyps	Polyps	not recorded	not recorded	SRP199550	68.98
SRR12904782	Polyps	Polyps	not recorded	not recorded	SRP199550	67.30
SRR12904781	Polyps	Polyps	not recorded	not recorded	SRP199550	64.61
SRR12710848	Polyps	Polyps	OA3 day3	not recorded	SRP199550	57.34
SRR12710847	Polyps	Polyps	OA3 day3	not recorded	SRP199550	56.59
SRR12710846	Polyps	Polyps	OA3 day3	not recorded	SRP199550	54.57
SRR12959184	Polyps	Polyps	E3 day0	not recorded	SRP199550	50.98
SRR12959214	Polyps	Polyps	E3 day9	not recorded	SRP199550	50.97
SRR12959182	Polyps	Polyps	E3 day0	not recorded	SRP199550	50.88
SRR12959215	Polyps	Polyps	E3 day9	not recorded	SRP199550	50.16
SRR12959190	Polyps	Polyps	E3 day21	not recorded	SRP199550	49.50
SRR12959202	Polyps	Polyps	E3 day15	not recorded	SRP199550	48.97
SRR12959183	Polyps	Polyps	E3 day0	not recorded	SRP199550	48.58
SRR12959188	Polyps	Polyps	E3 day21	not recorded	SRP199550	48.42
SRR12959201	Polyps	Polyps	E3 day15	not recorded	SRP199550	47.59
SRR12959216	Polyps	Polyps	E3 day9	not recorded	SRP199550	47.15
SRR12959189	Polyps	Polyps	E3 day21	not recorded	SRP199550	46.85
SRR12959203	Polyps	Polyps	E3 day15	not recorded	SRP199550	45.35
SRR12959230	Polyps	Polyps	E3 day3	not recorded	SRP199550	44.95
SRR12710858	Polyps	Polyps	OA3 day9	not recorded	SRP199550	38.59
SRR12710855	Polyps	Polyps	OA3 day9	not recorded	SRP199550	37.41
SRR12710857	Polyps	Polyps	OA3 day9	not recorded	SRP199550	36.84
SRR27940192	Polyps	Polyps	not recorded	not recorded	SRP199550	31.54
SRR12807381	Polyps	Polyps	OA3 day0	not recorded	SRP199550	0.00
SRR12849113	Polyps	Polyps	OA3 day0	not recorded	SRP199550	0.00
SRR12927880	Polyps	Polyps	E3 day0	not recorded	SRP199550	0.00
SRR12963484	Polyps	Polyps	E3 day0	not recorded	SRP199550	0.00
SRR9129316	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00
SRR9613519	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00

Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.