Genomic Location: chr2:62316728...62344918
NR annotation: XP_015758657.1, PREDICTED: GTPase-activating protein and VPS9 domain-containing protein 1-like [Acropora digitifera]
Species Montipora capricornis · all data for this species · gene families
| CDS |
| LOC138030468 |
| Transcript |
| rna-XM_068878378.1 |
| Protein |
| XP_068734479.1 |
| UniProt accession | Description |
|---|---|
| A5D794 | GTPase-activating protein and VPS9 domain-containing protein 1 OS=Bos taurus OX=9913 GN=GAPVD1 PE=2 SV=1 |
| A2RV61 | GTPase-activating protein and VPS9 domain-containing protein 1 OS=Xenopus laevis OX=8355 GN=gapvd1 PE=2 SV=1 |
| Q14C86 | GTPase-activating protein and VPS9 domain-containing protein 1 OS=Homo sapiens OX=9606 GN=GAPVD1 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0005854 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF00616 all species → | RasGAP | GTPase-activator protein for Ras-like GTPase | Family | Interproscan |
| PF18151 all species → | DUF5601 | Domain of unknown function (DUF5601) | Domain | Interproscan |
| PF02204 all species → | VPS9 | Vacuolar sorting protein 9 (VPS9) domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR003123 all species → | Domain | VPS9 domain | Interproscan |
| IPR045046 all species → | Family | Vacuolar protein sorting-associated protein 9-like | Interproscan |
| IPR001936 all species → | Domain | Ras GTPase-activating domain | Interproscan |
| IPR008936 all species → | Homologous_superfamily | Rho GTPase activation protein | Interproscan |
| IPR041545 all species → | Domain | RABX5, catalytic core helical domain | Interproscan |
| IPR037191 all species → | Homologous_superfamily | VPS9 domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR23101 all species → | RAB GDP/GTP EXCHANGE FACTOR | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005085 all species → | Molecular Function | guanyl-nucleotide exchange factor activity | Interproscan |
| GO:0005829 all species → | Cellular Component | cytosol | Interproscan |
| GO:0016192 all species → | Biological Process | vesicle-mediated transport | Interproscan |
| GO:0030139 all species → | Cellular Component | endocytic vesicle | Interproscan |
| GO:0031267 all species → | Molecular Function | small GTPase binding | Interproscan |
| GO:0043087 all species → | Biological Process | regulation of GTPase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K27566 | GAPVD1; GTPase-activating protein and VPS9 domain-containing protein 1 | - | Membrane trafficking | ko04131 | deepkoala |
Transcript abundance of XP_068734479.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 36 | 30 | 14.30 | 44.01 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR27940191 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 44.01 |
| SRR12904783 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 43.90 |
| SRR12786897 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 27.88 |
| SRR12786896 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 26.72 |
| SRR12904781 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 25.65 |
| SRR27940193 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 25.59 |
| SRR12786898 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 25.20 |
| SRR12904782 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 25.06 |
| SRR27940192 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 23.95 |
| SRR12959202 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 21.18 |
| SRR12959203 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 20.77 |
| SRR12959201 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 20.26 |
| SRR12959229 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 16.00 |
| SRR12959183 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 15.08 |
| SRR12959216 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 13.30 |
| SRR12959184 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 13.02 |
| SRR12959182 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 12.91 |
| SRR12959215 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 12.60 |
| SRR12959214 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 11.55 |
| SRR12710848 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 10.51 |
| SRR12710847 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 10.00 |
| SRR12959190 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 9.21 |
| SRR12710846 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 9.13 |
| SRR12959188 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 9.10 |
| SRR12959189 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 8.50 |
| SRR12959227 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 7.69 |
| SRR12710855 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 7.49 |
| SRR12710858 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 7.44 |
| SRR12710857 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 6.53 |
| SRR12959230 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 4.70 |
| SRR12807381 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12849113 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12927880 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12963484 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR9129316 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613519 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM,
StringTie quantification over 36 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 37 | XP_068720017.1 | 0.97888557748341 |
| Negatively correlated | 3 | XP_068724527.1 | -0.38096007018997 |
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | ready | open → |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |