Detailed information of XP_068735819.1 in Montipora capricornis

Genomic Location: chr14:13689013...13829924
NR annotation: XP_022807971.1, prolyl endopeptidase-like [Stylophora pistillata]
Species Montipora capricornis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
P48147Prolyl endopeptidase OS=Homo sapiens OX=9606 GN=PREP PE=1 SV=2
Q9QUR6Prolyl endopeptidase OS=Mus musculus OX=10090 GN=Prep PE=1 SV=1
P23687Prolyl endopeptidase OS=Sus scrofa OX=9823 GN=PREP PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0002682 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00326
all species →		Peptidase_S9Prolyl oligopeptidase familyDomainInterproscan
PF02897
all species →		Peptidase_S9_NProlyl oligopeptidase, N-terminal beta-propeller domainRepeatInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR051167
all species →		FamilyProlyl oligopeptidase and macrocyclaseInterproscan
IPR001375
all species →		DomainPeptidase S9, prolyl oligopeptidase, catalytic domainInterproscan
IPR002471
all species →		Active_sitePeptidase S9, serine active siteInterproscan
IPR029058
all species →		Homologous_superfamilyAlpha/Beta hydrolase foldInterproscan
IPR002470
all species →		FamilyPeptidase S9A, prolyl oligopeptidaseInterproscan
IPR023302
all species →		DomainPeptidase S9A, N-terminal domainInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR42881
all species →		PROLYL ENDOPEPTIDASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0005829
all species →		Cellular ComponentcytosolInterproscan
GO:0070012
all species →		Molecular Functionoligopeptidase activityInterproscan
GO:0006508
all species →		Biological ProcessproteolysisInterproscan
GO:0008236
all species →		Molecular Functionserine-type peptidase activityInterproscan
GO:0004252
all species →		Molecular Functionserine-type endopeptidase activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K01322PREP; prolyl oligopeptidaseEC:3.4.21.26
Peptidases and inhibitorsko01002deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068735819.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples
28TPM > 0
1Conditions
84.9Max TPM
22.8Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Polyps 36 28 22.83 84.91

Per sample · hover a bar for the full sample record

Show the sample table (36 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR12959229 Polyps Polyps E3 day3 not recorded SRP199550 84.91
SRR12959182 Polyps Polyps E3 day0 not recorded SRP199550 52.48
SRR12959183 Polyps Polyps E3 day0 not recorded SRP199550 46.44
SRR12959184 Polyps Polyps E3 day0 not recorded SRP199550 43.89
SRR12959201 Polyps Polyps E3 day15 not recorded SRP199550 41.28
SRR12959203 Polyps Polyps E3 day15 not recorded SRP199550 40.13
SRR12959202 Polyps Polyps E3 day15 not recorded SRP199550 39.45
SRR12959215 Polyps Polyps E3 day9 not recorded SRP199550 39.30
SRR12959214 Polyps Polyps E3 day9 not recorded SRP199550 34.24
SRR12959216 Polyps Polyps E3 day9 not recorded SRP199550 31.88
SRR27940193 Polyps Polyps not recorded not recorded SRP199550 28.69
SRR27940191 Polyps Polyps not recorded not recorded SRP199550 26.44
SRR12904783 Polyps Polyps not recorded not recorded SRP199550 26.43
SRR12959190 Polyps Polyps E3 day21 not recorded SRP199550 26.30
SRR12904781 Polyps Polyps not recorded not recorded SRP199550 25.41
SRR12959189 Polyps Polyps E3 day21 not recorded SRP199550 24.73
SRR12959188 Polyps Polyps E3 day21 not recorded SRP199550 23.77
SRR12904782 Polyps Polyps not recorded not recorded SRP199550 23.25
SRR12786898 Polyps Polyps OA3 day0 not recorded SRP199550 22.56
SRR12959227 Polyps Polyps E3 day3 not recorded SRP199550 21.47
SRR12786897 Polyps Polyps OA3 day0 not recorded SRP199550 21.34
SRR12786896 Polyps Polyps OA3 day0 not recorded SRP199550 18.82
SRR12710858 Polyps Polyps OA3 day9 not recorded SRP199550 18.10
SRR12710857 Polyps Polyps OA3 day9 not recorded SRP199550 16.95
SRR12710855 Polyps Polyps OA3 day9 not recorded SRP199550 13.64
SRR12710848 Polyps Polyps OA3 day3 not recorded SRP199550 11.01
SRR12710847 Polyps Polyps OA3 day3 not recorded SRP199550 9.89
SRR12710846 Polyps Polyps OA3 day3 not recorded SRP199550 9.24
SRR12807381 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12849113 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12927880 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12959230 Polyps Polyps E3 day3 not recorded SRP199550 0.00
SRR12963484 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR27940192 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9129316 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613519 Polyps Polyps not recorded not recorded SRP199550 0.00

Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated35XP_068731287.10.943973925253019
Negatively correlated3XP_068724527.1-0.373558765864695

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.readyopen →
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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