Detailed information of XP_068736412.1 in Montipora capricornis

Genomic Location: chr14:39565430...39600415
NR annotation: XP_020614421.1, nitric oxide synthase, brain-like [Orbicella faveolata]
Species Montipora capricornis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
O19132Nitric oxide synthase 1 OS=Oryctolagus cuniculus OX=9986 GN=NOS1 PE=2 SV=1
P29475Nitric oxide synthase 1 OS=Homo sapiens OX=9606 GN=NOS1 PE=1 SV=2
P29476Nitric oxide synthase 1 OS=Rattus norvegicus OX=10116 GN=Nos1 PE=1 SV=1
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0001036 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF00258
all species →
Flavodoxin_1FlavodoxinDomainInterproscan
PF00667
all species →
FAD_binding_1FAD binding domainDomainInterproscan
PF02898
all species →
NO_synthaseNitric oxide synthase, oxygenase domainDomainInterproscan
PF00175
all species →
NAD_binding_1Oxidoreductase NAD-binding domain DomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR001094
all species →
DomainFlavodoxin-likeInterproscan
IPR012144
all species →
FamilyNitric-oxide synthase, eukaryoteInterproscan
IPR017938
all species →
Homologous_superfamilyRiboflavin synthase-like beta-barrelInterproscan
IPR008254
all species →
DomainFlavodoxin/nitric oxide synthaseInterproscan
IPR039261
all species →
Homologous_superfamilyFerredoxin-NADP reductase (FNR), nucleotide-binding domainInterproscan
IPR029039
all species →
Homologous_superfamilyFlavoprotein-like superfamilyInterproscan
IPR017927
all species →
DomainFAD-binding domain, ferredoxin reductase-typeInterproscan
IPR044944
all species →
Homologous_superfamilyNitric oxide synthase, domain 3 superfamilyInterproscan
IPR044943
all species →
Homologous_superfamilyNitric oxide synthase, domain 1 superfamilyInterproscan
IPR003097
all species →
DomainSulfite reductase [NADPH] flavoprotein alpha-component-like, FAD-bindingInterproscan
IPR050607
all species →
FamilyNitric Oxide Synthase (NOS)Interproscan
IPR044940
all species →
Homologous_superfamilyNitric oxide synthase, domain 2 superfamilyInterproscan
IPR036119
all species →
Homologous_superfamilyNitric oxide synthase, N-terminal domain superfamilyInterproscan
IPR004030
all species →
DomainNitric oxide synthase, N-terminalInterproscan
IPR023173
all species →
Homologous_superfamilyNADPH-cytochrome p450 reductase, FAD-binding, alpha-helical domain superfamilyInterproscan
IPR001433
all species →
DomainOxidoreductase FAD/NAD(P)-bindingInterproscan
IPR001709
all species →
DomainFlavoprotein pyridine nucleotide cytochrome reductaseInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR43410
all species →
NITRIC OXIDE SYNTHASE OXYGENASEInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0010181
all species →
Molecular FunctionFMN bindingInterproscan
GO:0004517
all species →
Molecular Functionnitric-oxide synthase activityInterproscan
GO:0005516
all species →
Molecular Functioncalmodulin bindingInterproscan
GO:0006809
all species →
Biological Processnitric oxide biosynthetic processInterproscan
GO:0020037
all species →
Molecular Functionheme bindingInterproscan
GO:0050660
all species →
Molecular Functionflavin adenine dinucleotide bindingInterproscan
GO:0050661
all species →
Molecular FunctionNADP bindingInterproscan
GO:0016491
all species →
Molecular Functionoxidoreductase activityInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K13241NOS2; nitric-oxide synthase, inducibleEC:1.14.13.39
Pathways of neurodegeneration - multiple diseasesko05022deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068736412.1 across 36 RNA-seq samples of Montipora capricornis. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples
0TPM > 0
1Conditions
0.0Max TPM
0.0Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Polyps 36 0 0.00 0.00

Per sample · hover a bar for the full sample record

Show the sample table (36 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR12710846 Polyps Polyps OA3 day3 not recorded SRP199550 0.00
SRR12710847 Polyps Polyps OA3 day3 not recorded SRP199550 0.00
SRR12710848 Polyps Polyps OA3 day3 not recorded SRP199550 0.00
SRR12710855 Polyps Polyps OA3 day9 not recorded SRP199550 0.00
SRR12710857 Polyps Polyps OA3 day9 not recorded SRP199550 0.00
SRR12710858 Polyps Polyps OA3 day9 not recorded SRP199550 0.00
SRR12786896 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12786897 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12786898 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12807381 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12849113 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12904781 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR12904782 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR12904783 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR12927880 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12959182 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12959183 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12959184 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12959188 Polyps Polyps E3 day21 not recorded SRP199550 0.00
SRR12959189 Polyps Polyps E3 day21 not recorded SRP199550 0.00
SRR12959190 Polyps Polyps E3 day21 not recorded SRP199550 0.00
SRR12959201 Polyps Polyps E3 day15 not recorded SRP199550 0.00
SRR12959202 Polyps Polyps E3 day15 not recorded SRP199550 0.00
SRR12959203 Polyps Polyps E3 day15 not recorded SRP199550 0.00
SRR12959214 Polyps Polyps E3 day9 not recorded SRP199550 0.00
SRR12959215 Polyps Polyps E3 day9 not recorded SRP199550 0.00
SRR12959216 Polyps Polyps E3 day9 not recorded SRP199550 0.00
SRR12959227 Polyps Polyps E3 day3 not recorded SRP199550 0.00
SRR12959229 Polyps Polyps E3 day3 not recorded SRP199550 0.00
SRR12959230 Polyps Polyps E3 day3 not recorded SRP199550 0.00
SRR12963484 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR27940191 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR27940192 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR27940193 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9129316 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613519 Polyps Polyps not recorded not recorded SRP199550 0.00

Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated0not in this network-
Negatively correlated0not in this network-

This gene has no edge at all in the Montipora capricornis network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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