Gene detail

Detailed information of XP_068736487.1 in Montipora capricornis

Genomic Location: chr14:24762114...24777324
NR annotation: XP_029207195.2, dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial-like isoform X1 [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_068880386.1

GAATAAGAATGTGAGAGGGCTCCTTTGGAATGATACAAGGATCAATACCCGGGGAAAAACATGCTCTCAGCTAGACGTGTGATTCATTATTTGGGACGGAAGGAGAGTTCTGTAGCTCTCAGAACAGTTGTTTGCAAGGGTCGAACGCTGGTTCAGAGACGAACAGTTGCGATTTGGCGTGCGAGGGATTCAACTGGTTTTCGTCAAGTGTTTTGTTCAGGTTCACCAAGACATGGTTTTCGACTTTTCAGCTCCAAGGACCTCCCTTCTCACACAAAAGTCACGTTACCAGCATTGTCTCCAACAATGGAGATGGGAACAATTGTCAGTTGGGAGAAACGAGAGGGTGATGCGCTGAACGAGGGAGATCTCCTGGCACAGATTGAGACTGACAAAGCTACAATGGAATTTGAAACTCCAGAAGAGGGATTCTTGGCAAAGATTATTCTTCCAGCTGGAAGCAAGGATGTACCCATTGGCAAACTGCTTTGTATCATAGTGGAAAATAAAGAAGACATTGATTCTTTTAAGGACTTTGTGGCTGGAGAAGAGGCAAGCCCGGCTGTTGAGAAGCCTGCTGAAGCTGCTGTCCCACAACCTCCCCCACCTCAAGGCCCATCACCCCCGACCCCACCACCACCATCAGTAACTCGTGCTTCTTCACCACCCTCTCCACCCTCAGTAGCACCAGGTGGTAGAGTGTTTGCCAGTCCATTGGCAAAGAAGATGGCTCAAGAGAAAGGCATTGATTTAGCTTCTTTACAAGGCAGTGGTCCTGGAGGCCGAGTGGTTGCACAGGATGTGTCTGTGACAATGCCAGCTGCCACTGCTGCACCCACTCCAGTTTTTGTGCCAGGAGCAGAATTCACTGACTTTCCTCTTACAAATGTTAGAAAGGTTATTGCTAAAAGACTCTTGGAATCCAAACAAACAATTCCTCATTATTATCTGTCAGTGGACATTCGAATGGATGATTTATTAGACGTTCGAAAGCAGTTAAACTCGGATTTAGATGGAGCACATAAACTGTCTGTGAATGACTTTGTGCTGAAAGCTTGTGCATTGGCTTGTAAAAGAGTTCCTGAAGCTAACTCCTCCTGGATGTCAGATTTTATAAGACAacatcATAATGTTGATATTAGCGTGGCAGTCAGTGCAGAATCTGGTTTAATCACACCTATTGTCTTCAATGCAGATAAAAAGGGTCTAAAAGATATAAGCTCAGACATAACTGCTTTAGCTGAGAAAGCAAGAGAGAACAAGTTACAACCACATGAGTTCCAGGGTGGCACCATCACAGTTTCAAATCTAGGAATGTTTGGTGTGAAGAATTTTTCGGCAATTATTAACCCGCCCCAAGCTTGTATATTAGCGGTTGGAAAAGCCGAGAAACAAGTTATAGTGGATGAAAATAGCGAAAAGGGGTACACAACTGGGACAGTAATGTCCGTGACCCTTAGCTGTGATCATCGTGTTGTTGATGGTGCTGTTGGAGCGCAGTGGCTGGCGGCATTTAAAGGCTATTTAGAGAAACCACTGACTATGTTACTATGATCCGAAACAAGAGATTAATTTTCTTGTCCGAAATTAATAACAAATTCCATGATTACAGCTTAAAAAGTCAAGGGATGGGTAACAAGGGGCTATAAATGCGGCGTTggagagggaaggggggggggggggggcaattaGAACTCGGAAAGCGATGAGTACTGAGGTGAGAACGGAAGGTCAGCGGAAGAGAATATAATTCAGTGCTAGAAAAGATAGAATTTGCGTGAGGAAGGAACGAAAACGGGACGTAATATAGAGATGGAGGAGTCTTAAGTTCATATCGTTCTTTccgtttttttccttcttttcgtCCTACACTTATTTTTCCCCTTCCCTTTCCGCTTATAGCTCCACCCGCAAATCTAGCTCAAAATATTCAAACTTTTGAATTCTCATTGTCTTTCTATTTGGGATGGACGATGAAGTGAGGTTCGCTTACTATTTGAACGGAGCTTTAGGTGAAATTGTTTTGAAGTGTGTTCGTGGTGTCCCTTTTGAACGTAAGGGAACAGAACAAGGCTGCTGAAAGGAAAGGATTCTAAATGCAAATCAAGATGACCTCAATGACATGTGACCAGGGACTAAATCTCAAGATCATGAGCACCGGGCTGTAATTGGCCAATGGCAAAAACAGTTTGGATAGTTAATTTTATCGTTCTTGGTTTAGCTCCGCGTGACAAAAGATTAATTCTCCCTATGAAGCTCAATAAAGTAGAAAAAAATTCGCTTGTTCCGGTAAATtcctagaaaaaaaattcctcggaagattttctttttttctcgtgAGTAATCATTTCCAGAAGATATATGGCAAGGGCCTCAACTTTTAAAGCCCCTATAAAACCATTGATTGACAAATTCTCCACACTCTTTCCCGTATATTTTGAACGGTCTTTGTTGGGAGAATTTGTCTAAATCGAACTGTTGGCAAGTTGTATTCgtgtaattattattagtatttttttaattggtgaaattgaaaagaaaaacacgaaTGGCCCGTTTTTATGGGATTTCACGGGCTGATATGAGGATAATTTCCATTAGTCCAGCCAGAGTACAGATTCATTTCCGGCCGAAAAAACAACGGACCTGTGAATTAGCCTACAACCACAGCAACATATttagaatttgtttttttaagatCATTAATCATTGAAAACTACGAGACTTGGATTTTCGTTTTTGTGACTACGTACAATGGTTGCAAatgagaaattattattataa

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q8BMF4	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Mus musculus OX=10090 GN=Dlat PE=1 SV=2
P11180	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex OS=Bos taurus OX=9913 GN=DLAT PE=1 SV=2
Q19749	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex, mitochondrial OS=Caenorhabditis elegans OX=6239 GN=dlat-1 PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0001901 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00198 all species →	2-oxoacid_dh	2-oxoacid dehydrogenases acyltransferase (catalytic domain)	Domain	Interproscan
PF02817 all species →	E3_binding	e3 binding domain	Family	Interproscan
PF00364 all species →	Biotin_lipoyl	Biotin-requiring enzyme	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR000089 all species →	Domain	Biotin/lipoyl attachment	Interproscan
IPR003016 all species →	Binding_site	2-oxo acid dehydrogenase, lipoyl-binding site	Interproscan
IPR023213 all species →	Homologous_superfamily	Chloramphenicol acetyltransferase-like domain superfamily	Interproscan
IPR011053 all species →	Homologous_superfamily	Single hybrid motif	Interproscan
IPR045257 all species →	Family	Dihydrolipoamide acetyltransferase/Pyruvate dehydrogenase protein X component	Interproscan
IPR001078 all species →	Domain	2-oxoacid dehydrogenase acyltransferase, catalytic domain	Interproscan
IPR036625 all species →	Homologous_superfamily	E3-binding domain superfamily	Interproscan
IPR004167 all species →	Domain	Peripheral subunit-binding domain	Interproscan
IPR006257 all species →	Family	Dihydrolipoyllysine-residue acetyltransferase component of pyruvate dehydrogenase complex	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR23151 all species →	DIHYDROLIPOAMIDE ACETYL/SUCCINYL-TRANSFERASE-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0004742 all species →	Molecular Function	dihydrolipoyllysine-residue acetyltransferase activity	Interproscan
GO:0005967 all species →	Cellular Component	obsolete mitochondrial pyruvate dehydrogenase complex	Interproscan
GO:0006086 all species →	Biological Process	acetyl-CoA biosynthetic process from pyruvate	Interproscan
GO:0045254 all species →	Cellular Component	pyruvate dehydrogenase complex	Interproscan
GO:0016746 all species →	Molecular Function	acyltransferase activity	Interproscan
GO:0006090 all species →	Biological Process	pyruvate metabolic process	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K00627	DLAT, aceF, pdhC; pyruvate dehydrogenase E2 component (dihydrolipoyllysine-residue acetyltransferase)	EC:2.3.1.12	Lipoic acid metabolism	ko00785	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068736487.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples

30TPM > 0

1Conditions

62.8Max TPM

19.1Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
Polyps	36	30	19.12	62.82

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR12959230	Polyps	Polyps	E3 day3	not recorded	SRP199550	62.82
SRR27940191	Polyps	Polyps	not recorded	not recorded	SRP199550	42.81
SRR12904783	Polyps	Polyps	not recorded	not recorded	SRP199550	41.97
SRR27940192	Polyps	Polyps	not recorded	not recorded	SRP199550	31.20
SRR12786897	Polyps	Polyps	OA3 day0	not recorded	SRP199550	29.62
SRR12786898	Polyps	Polyps	OA3 day0	not recorded	SRP199550	28.79
SRR12786896	Polyps	Polyps	OA3 day0	not recorded	SRP199550	27.92
SRR27940193	Polyps	Polyps	not recorded	not recorded	SRP199550	27.80
SRR12904781	Polyps	Polyps	not recorded	not recorded	SRP199550	27.43
SRR12904782	Polyps	Polyps	not recorded	not recorded	SRP199550	26.62
SRR12959216	Polyps	Polyps	E3 day9	not recorded	SRP199550	23.78
SRR12959215	Polyps	Polyps	E3 day9	not recorded	SRP199550	21.77
SRR12959227	Polyps	Polyps	E3 day3	not recorded	SRP199550	21.03
SRR12959214	Polyps	Polyps	E3 day9	not recorded	SRP199550	20.66
SRR12959202	Polyps	Polyps	E3 day15	not recorded	SRP199550	20.64
SRR12959184	Polyps	Polyps	E3 day0	not recorded	SRP199550	19.78
SRR12959182	Polyps	Polyps	E3 day0	not recorded	SRP199550	19.28
SRR12959229	Polyps	Polyps	E3 day3	not recorded	SRP199550	19.24
SRR12959201	Polyps	Polyps	E3 day15	not recorded	SRP199550	18.93
SRR12959183	Polyps	Polyps	E3 day0	not recorded	SRP199550	18.70
SRR12710857	Polyps	Polyps	OA3 day9	not recorded	SRP199550	18.42
SRR12959203	Polyps	Polyps	E3 day15	not recorded	SRP199550	17.98
SRR12710855	Polyps	Polyps	OA3 day9	not recorded	SRP199550	15.13
SRR12710858	Polyps	Polyps	OA3 day9	not recorded	SRP199550	15.06
SRR12959189	Polyps	Polyps	E3 day21	not recorded	SRP199550	14.37
SRR12959188	Polyps	Polyps	E3 day21	not recorded	SRP199550	12.59
SRR12959190	Polyps	Polyps	E3 day21	not recorded	SRP199550	12.03
SRR12710847	Polyps	Polyps	OA3 day3	not recorded	SRP199550	11.31
SRR12710846	Polyps	Polyps	OA3 day3	not recorded	SRP199550	11.22
SRR12710848	Polyps	Polyps	OA3 day3	not recorded	SRP199550	9.50
SRR12807381	Polyps	Polyps	OA3 day0	not recorded	SRP199550	0.00
SRR12849113	Polyps	Polyps	OA3 day0	not recorded	SRP199550	0.00
SRR12927880	Polyps	Polyps	E3 day0	not recorded	SRP199550	0.00
SRR12963484	Polyps	Polyps	E3 day0	not recorded	SRP199550	0.00
SRR9129316	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00
SRR9613519	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00

Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.