Gene detail

Detailed information of XP_068744566.1 in Montipora capricornis

Genomic Location: chr3:21320691...21389478
NR annotation: XP_044172914.1, LOW QUALITY PROTEIN: Werner syndrome ATP-dependent helicase-like [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

LOC138042538

ATGGATATAAGTAAAGAACACAACATGGACGTGAGTTACATTTGTGATGAGACGAAAGACCTGATTGATTTAAGTGACGAGGAACTTGATGGAGCAATGGCTGAGGTTGATATAGAGGAACTCTGCAACCAAAGCCAGGTGGAACCAGAGACTTCTGAAGATAGTCACAAGGATGCTCAGGACAAATTAGCACCAACTCATGAGACTACTGAAATTAAACCCGATATTGAGTATATTGAGGTCCTGAAGAAATTCTTTGGACATAGCAAGTTCAGGCCTATGCAGTGGAAGATAATCAATGAAGTGCTCAATCACAAACGAGATGTCTGTGTTGTTATGGCAACAGGATATGGCAAAAGTTTGTGCTACCAGTTTCCATCTTTGTACACTGGAGGAACAACTGCTGTCATATCACCCTTGATTTCACTCATGGAGGATCAAGTAGCCAAACTAAAGCTTTATAAAATTCCTGCTTGTTATCTTGGTTCTGCTCAAAGCAACAATGCCGAAGCAAAAGCAGGGGTTTTGAGAGGTGAATATCGAGTGGTGTACTTGACTCCTGAATATGCTTCCCTAGACACAGAATTTTTAGCACGGGTGCAGACATCTGTAGGTCTAACCCTAGTTGCAATAGATGAAGCTCATTGCGTCTCTCAGTGGGGACATGACTTCAGATCCTCTTATCGTTTACTTGGATGTATTCGGGATAAGCTTCCTGAGGTACCTATTGTGGCCCTGACAGCTACTGCCACTCCTGTTGTTAGAAAAGATATTTGTCAGTCTCTGAAGCTAAAGAATGCTAGTTATGTTTGTACAGGGTTTGACAGACCTAATTTATACTTTGAGGTATCAAGAAAGTCTAGCAGCATAAAGGATGACTTTAAACCTCTTTTGATGAGAACTGGAGATAGAACAAAGATTGAATATTCATTTGATGGTCCTACAATAGTTTACTGCCCAACAAGGAAAGCAACTGAAACTGTAGCAAGAGAACTTCATGGTCTTGGGGTTAACTGTGAATATTACCATGCTGGTCTAAGCAACAATGAACGTAAACGGGTGCATCACTTGTTTATCAGGGATGAAATTCAGTGCATTGTAGCTACAGTAGCATTTGGAATGGGAATCGATAAACCGGACGTCAGAAAAATTATACACCATGGAGCTCCTAGGGATATAGAATCATATTACCAAGAGATAGGAAGAGCTGGCCGAGATGGCCTTCCCAGCACTTGTCATGTTTTCTACAGTACTGCAGACTTTGTTCTAAACCGGCGTTTATTAAATGAATTGTCTGCACAGTCTTTTAAAGAACACAAGCTGAAGATGCTGAACAAACTTGAGCAGTACCTAACTACAACAGACTGTAGAAGAAGAACAATTCTAGCTTACTTTGAGGATAAGGATGATACAAGCTATGGTGGAAAGGATGACTGCTGTGATAACTGTCGAAACAGAGCCCTTAACCCATGTATAAAGGAAGAAAAGGAAGATTTTACCAAGGAAGCGAAATTACTCCTTAGTGCTGTAATGTGTACTGGAAATGGCAGGTTTGGTATATCAGTTCCTGTCTTGCTGTTGAAAGGTTCAAACAGCAGTAAAGCCCCACATTGGTTGACCACAAAGAAAGAATTTGGAGCTGGCAATTTTCACTCTGACAAGTGGTGGAAGAGTTTTGGCCGTCAACTCATGAACTTGGGGTTTCTTCAAGAAAAAACTAATCCAGGTGGTTTTGGCTCTCTTACAGCTCTTTCAGCCAAAGGAGAAAAATGGCTGACAGAAGCTTCAAGGAACGAAGCTGTCAAAATGATGTTCACCCCGAACCAGGATCTTTTGTCATCGGAAAAGCAGGCACTCAAAATTATAATTCCTGTGAAAAATGTTGTGGCTTCTACAACATGGCAACAGGCTCAAGGAACCCAGCTGGTCAATTCCTCGGTAAAACCAGTTATTGATGAAAAGGAATTGGAACTTCAGGGATCTTTGTATACCACCCTTTTGAAGCTAAGAACAGAATTGTCACACACTCTAGATTGCCCGCCTTACATGATCGCTACAAACAAAATCCTCCTGGATATTGCCAAACACAGACCGTCCAGCATCGATTCACTTCTGAGAGTAGATGGAGTTTCTGAGAGACAATGTGAACGGTTTGGTCAACAGCTTGTTAACTGTGTAGCGACTTTCTGCAAGGAAAATAAACTCGAGGCTGACAACATTGATGACCACACGGATTCAACTAACTTGGCAGAGCCGGGAGGAACTTTCCGACGTGAACTCAGTCAAACTGTGATAATGACGTATAATCTGTTTCACGAGAACCAGATGAGTATTAAAGAAGTGGCTAAATCCAGGAACATGGTTGAGGGAACAATTTTTGGTCATCTGGCTGATGCTCTTAAGGCTGGTTATCCTGTGGATTACAAGAGAGCCGGGCTGACTGATGAAGTGCGAGAGTTAGTGACCAAAACTATCCGGTCGCCACCAATTAATTCAGACATTAGCAAGTTATCGGTGATAAAAGACCGCTTGCCTGATCACGTCAATTATGGCCAAATTAAGTTGGTAATCGCTATTTTAGAGATGTCTTGTCAGACGGCCTCATGCAGCACCCCAGTCGAGCCCCAGAAAAAGAGCTCCTTCACCTCTGGTACCGCCCTAGGGAATGCGCCAAGTAATCGCCGACCCTCTTCACAAGACACGGCGAGAAAACTTCCAGTATGGTTGTCTGGGAAACCGGGCGGAAAGAGAAAGAATCCATTTTGA

Transcript

rna-XM_068888465.1

aattttcattttacagacggtctgaacagtctgcgtttttcagtgtccctgccaaaccagccttcttcagGATTCAATGGATATAAGTAAAGAACACAACATGGACGTGAGTTACATTTGTGATGAGACGAAAGACCTGATTGATTTAAGTGACGAGGAACTTGATGGAGCAATGGCTGAGGTTGATATAGAGGAACTCTGCAACCAAAGCCAGGTGGAACCAGAGACTTCTGAAGATAGTCACAAGGATGCTCAGGACAAATTAGCACCAACTCATGAGACTACTGAAATTAAACCCGATATTGAGTATATTGAGGTCCTGAAGAAATTCTTTGGACATAGCAAGTTCAGGCCTATGCAGTGGAAGATAATCAATGAAGTGCTCAATCACAAACGAGATGTCTGTGTTGTTATGGCAACAGGATATGGCAAAAGTTTGTGCTACCAGTTTCCATCTTTGTACACTGGAGGAACAACTGCTGTCATATCACCCTTGATTTCACTCATGGAGGATCAAGTAGCCAAACTAAAGCTTTATAAAATTCCTGCTTGTTATCTTGGTTCTGCTCAAAGCAACAATGCCGAAGCAAAAGCAGGGGTTTTGAGAGGTGAATATCGAGTGGTGTACTTGACTCCTGAATATGCTTCCCTAGACACAGAATTTTTAGCACGGGTGCAGACATCTGTAGGTCTAACCCTAGTTGCAATAGATGAAGCTCATTGCGTCTCTCAGTGGGGACATGACTTCAGATCCTCTTATCGTTTACTTGGATGTATTCGGGATAAGCTTCCTGAGGTACCTATTGTGGCCCTGACAGCTACTGCCACTCCTGTTGTTAGAAAAGATATTTGTCAGTCTCTGAAGCTAAAGAATGCTAGTTATGTTTGTACAGGGTTTGACAGACCTAATTTATACTTTGAGGTATCAAGAAAGTCTAGCAGCATAAAGGATGACTTTAAACCTCTTTTGATGAGAACTGGAGATAGAACAAAGATTGAATATTCATTTGATGGTCCTACAATAGTTTACTGCCCAACAAGGAAAGCAACTGAAACTGTAGCAAGAGAACTTCATGGTCTTGGGGTTAACTGTGAATATTACCATGCTGGTCTAAGCAACAATGAACGTAAACGGGTGCATCACTTGTTTATCAGGGATGAAATTCAGTGCATTGTAGCTACAGTAGCATTTGGAATGGGAATCGATAAACCGGACGTCAGAAAAATTATACACCATGGAGCTCCTAGGGATATAGAATCATATTACCAAGAGATAGGAAGAGCTGGCCGAGATGGCCTTCCCAGCACTTGTCATGTTTTCTACAGTACTGCAGACTTTGTTCTAAACCGGCGTTTATTAAATGAATTGTCTGCACAGTCTTTTAAAGAACACAAGCTGAAGATGCTGAACAAACTTGAGCAGTACCTAACTACAACAGACTGTAGAAGAAGAACAATTCTAGCTTACTTTGAGGATAAGGATGATACAAGCTATGGTGGAAAGGATGACTGCTGTGATAACTGTCGAAACAGAGCCCTTAACCCATGTATaaaggaagaaaaggaagaTTTTACCAAGGAAGCGAAATTACTCCTTAGTGCTGTAATGTGTACTGGAAATGGCAGGTTTGGTATATCAGTTCCTGTCTTGCTGTTGAAAGGTTCAaacAGCAGTAAAGCCCCACATTGGTTGACCACAAAGAAAGAATTTGGAGCTGGCAATTTTCACTCTGACAAGTGGTGGAAGAGTTTTGGCCGTCAACTCATGAACTTGGGGTTTCTTCAAGAAAAAACTAATCCAGGTGGTTTTGGCTCTCTTACAGCTCTTTCAGCCAAAGGAGAAAAATGGCTGACAGAAGCTTCAAGGAACGAAGCTGTCAAAATGATGTTCACCCCGAACCAGGATCTTTTGTCATCGGAAAAGCAGGCACTCAAaattatAATTCCTGTGAAAAATGTTGTGGCTTCTACAACATGGCAACAGGCTCAAGGAACCCAGCTGGTCAATTCCTCGGTAAAACCAGTTATTGATGAAAAGGAATTGGAACTTCAGggaTCTTTGTATACCACCCTTTTGAAGCTAAGAACAGAATTGTCACACACTCTAGATTGCCCGCCTTACATGATCGCTACAAACAAAATCCTCCTGGATATTGCCAAACACAGACCGTCCAGCATCGATTCACTTCTGAGAGTAGATGGAGTTTCTGAGAGACAATGTGAACGGTTTGGTCAACAGCTTGTTAACTGTGTAGCGACTTTCTGCAAGGAAAATAAACTCGAGGCTGACAACATTGATGACCACACGGATTCAACTAACTTGGCAGAGCCGGGAGGAACTTTCCGACGTGAACTCAGTCAAACTGTGATAATGACGTATAATCTGTTTCACGAGAACCAGATGAGTATTAAAGAAGTGGCTAAATCCAGGAACATGGTTGAGGGAACAATTTTTGGTCATCTGGCTGATGCTCTTAAGGCTGGTTATCCTGTGGATTACAAGAGAGCCGGGCTGACTGATGAAGTGCGAGAGTTAGTGACCAAAACTATCCGGTCGCCACCAATTAATTCAGacATTAGCAAGTTATCGGTGATAAAAGACCGCTTGCCTGATCACGTCAATTATGGCCAAATTAAGTTGGTAATCGCTATTTTAGAGATGTCTTGTCAGACGGCCTCATGCAGCACCCCAGTCGAGCCCCAGAAAAAGAGCTCCTTCACCTCTGGTACCGCCCTAGGGAATGCGCCAAGTAATCGCCGACCCTCTTCACAAGACACGGCGAGAAAACTTCCAGTATGGTTGTCTGGGAAACCGGGCGGAAAGAGAAAGAATCCATTTTGAATTTAATATAGACTCGtgcacatgttaatttttgtAGACTTGTGCGTGAAGTTAGGAACTTTTTTTCCATCAGATTTTGCGGACACGTTATTCAACTAGCTTTGGCTCTACTTTGTTGATGTCGATAAACTGtgataaatttaaaattattgtaaataaggGAGTTAACCAAGGGTTAACAGTGTGTAGTCTCGAAAGCGAAAATGGACTTTGACGAACAACATTCTATCCAAGAGGAATACGCCAACCCTAACGATGCATCTATATGAAGGACGTTTGAGATTACTATGAAAATTGCCCAGATCAAGAAGACAATCAGGACAAGAAAGCCGATGGAGTTGTGTTTGCTACTACAGGACCGTCTTCATTCTCATTCTATTTTTCCTCTCTTGTTAAGGTGGTATTTGCCTTTGTTATGAAATGGGACGGACATTACCACTCACGCCACTCACGAGACAAGGCAATTCGCGTATCAAGTGCAGGGAAATGCGTGCCAGGTGGTCCAGACGAAGATACACCGCATCTGTTTAAACTGCGATAAACGTAAATGAGTCTCGACAATTCCATTATCACCACAAGTTCAGTATAGTCCTCGATCTCACCATGCCAATCATTGGTTTACGCCGAAGCGGGACTCTACTGAAAAAGGGTCGAGTCACAAAGAGTTTTTAGGTTTTCTTTATATATCGAAGTGGGACTGGTCTTTTTTGGAAGCTAAAGAAggttaaacaagaaaaatactgtttattttAGTTACAATTTGTTGATActttatttgtttactttccCTGGAAGGAGTGGTTTATTGTGGCAAGGTTTCAGCGAAATGTATCCTCACTGTCACGGGCGAGATTCGCATTACGGAGTAGATAGAGGTGCGAGACTAACAGCTGTGTCTTACGGCACACCCTTGTAGGGGGCGTaacggggttttttttttctcagtgcgttagcgggcggaattcaacaaatcctgcaatctgattggtttcgggagcgggtggaattttctcatccggcccgCTCACGGcgggcggaatcctagccttAGTTGCGTGAGCTTttgtgatgaccttaaatttcctttttttcgacatcgaatccgtttacatacagaaggtactttttattagacaagaggtttggaaattggattcaaataaaaatatttctctttgaaa

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q14191	Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN OS=Homo sapiens OX=9606 GN=WRN PE=1 SV=2
O09053	Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN OS=Mus musculus OX=10090 GN=Wrn PE=1 SV=3
O93530	Bifunctional 3'-5' exonuclease/ATP-dependent helicase WRN OS=Xenopus laevis OX=8355 GN=wrn PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0000285 (this species only)

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF00271 all species →	Helicase_C	Helicase conserved C-terminal domain	Domain	Interproscan
PF09382 all species →	RQC	RQC domain	Domain	Interproscan
PF16124 all species →	RecQ_Zn_bind	RecQ zinc-binding	Domain	Interproscan
PF00570 all species →	HRDC	HRDC domain	Domain	Interproscan
PF14493 all species →	HTH_40	Helix-turn-helix domain	Domain	Interproscan
PF00270 all species →	DEAD	DEAD/DEAH box helicase	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR002121 all species →	Domain	HRDC domain	Interproscan
IPR001650 all species →	Domain	Helicase, C-terminal domain-like	Interproscan
IPR018982 all species →	Domain	RQC domain	Interproscan
IPR044876 all species →	Homologous_superfamily	HRDC domain superfamily	Interproscan
IPR032284 all species →	Domain	ATP-dependent DNA helicase RecQ, zinc-binding domain	Interproscan
IPR036388 all species →	Homologous_superfamily	Winged helix-like DNA-binding domain superfamily	Interproscan
IPR027417 all species →	Homologous_superfamily	P-loop containing nucleoside triphosphate hydrolase	Interproscan
IPR014001 all species →	Domain	Helicase superfamily 1/2, ATP-binding domain	Interproscan
IPR029491 all species →	Domain	Helicase Helix-turn-helix domain	Interproscan
IPR004589 all species →	Family	DNA helicase, ATP-dependent, RecQ type	Interproscan
IPR011545 all species →	Domain	DEAD/DEAH box helicase domain	Interproscan
IPR036390 all species →	Homologous_superfamily	Winged helix DNA-binding domain superfamily	Interproscan
IPR010997 all species →	Homologous_superfamily	HRDC-like superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR13710 all species →	DNA HELICASE RECQ FAMILY MEMBER	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0003676 all species →	Molecular Function	nucleic acid binding	Interproscan
GO:0006260 all species →	Biological Process	DNA replication	Interproscan
GO:0006281 all species →	Biological Process	DNA repair	Interproscan
GO:0043138 all species →	Molecular Function	3'-5' DNA helicase activity	Interproscan
GO:0004386 all species →	Molecular Function	helicase activity	Interproscan
GO:0006310 all species →	Biological Process	DNA recombination	Interproscan
GO:0005524 all species →	Molecular Function	ATP binding	Interproscan
GO:0000166 all species →	Molecular Function	nucleotide binding	Interproscan
GO:0044237 all species →	Biological Process	obsolete cellular metabolic process	Interproscan
GO:0000723 all species →	Biological Process	telomere maintenance	Interproscan
GO:0000724 all species →	Biological Process	double-strand break repair via homologous recombination	Interproscan
GO:0005634 all species →	Cellular Component	nucleus	Interproscan
GO:0005654 all species →	Cellular Component	nucleoplasm	Interproscan
GO:0005694 all species →	Cellular Component	chromosome	Interproscan
GO:0005737 all species →	Cellular Component	cytoplasm	Interproscan
GO:0006268 all species →	Biological Process	DNA unwinding involved in DNA replication	Interproscan
GO:0009378 all species →	Molecular Function	four-way junction helicase activity	Interproscan
GO:0032508 all species →	Biological Process	DNA duplex unwinding	Interproscan
GO:0044806 all species →	Biological Process	G-quadruplex DNA unwinding	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K10900	WRN, RECQL2; werner syndrome ATP-dependent helicase	EC:5.6.2.4	DNA repair and recombination proteins	ko03400	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.