Gene detail

Detailed information of XP_068746743.1 in Montipora capricornis

Genomic Location: chr3:74369171...74398679
NR annotation: XP_029211985.2, cathepsin L-like [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families

Gene Structure

More details in JBrowse

Sequence

CDS

Transcript

rna-XM_068890642.1

tcatGTGACCCTATTGCTGTTATTGCAAACAGAAACATGGAGCTGTACTTTGTTGTTTTACTGTCTATCCTTGCTCCATCTTCCCTTCGATCTGAGAAAATCGTAGGAGGAATAGAGGATAGAAAGCACGATGACCCAGATGTACTTAATGCGCTCGATTTTGCCATGAACGAATTTAACGCCATGCAAAACAACATGTATCGTATGATGGCAACGAAAGTTGAGGATGCAACTTTTcagCTAGTTGCAGGTCAGAAGTTCTGTGTTGTCGCAGAGGTTGGAGTCTCACGGAGCTGTCGTAATGATGATGCTCACAAGTCAGCTTCATTGGATATCTGTCCTGTAGATACTCTGGAGATGCATTGCAAGTTTGTGGTTATTAATGTTCCATGGGAGAAGCGAAAAGAGCTGGTTACCCATGAATGCATAGGACTGAAAGAGAGGATGCTGTCGTGTGAGAGAAGCCAACCAGTAGATACTCCTGAAATAAATGAGAATGTCGTTAAGGAAATGTTTGACAAGACTACTGCACAAACAGATGATGACGTGGAAGAGACATTTAGAAAATTTATCGTGCAACACAAGAAGCCATACTTAAATGATAAAGATGAGTATGCAAAGCGCTTTGCAATTTTCCAAGAGAATTTGGTCAAAGCTCGTAAGATGCAGGATATGGACAGGGGGTCTGCAAAATATGGAGTGACTGTGTTCAGTGATCTTACAGAGGAGGAATTCAAGAAATATTACAGGATGCCAGGATGGGGAAAACCTCTGTATGAGATGAAGGAAGCTGAGATACCAAAAGGCGATATTCCAACAGCATTTGATTGGAGGGATAAAGGTGCAGTGACTGCTGTTAAGAACCAGGGAATGTGTGGGTCATGCTGGGCCTTTTCGACTACCGGAAATATTGAGGGACAGTGGAAAATCAAGAAAGGGCAACTTGTCTCTCTCAGTGAGCAAGAACTTGTTGATTGCGATAAAGTTGACCAAGGCTGTGAAGGTGGACTTCCTGCCAATGCTTACAAGCAAATCATCAAACTTGgtGGACTTGAGGCGGAGAAAGAGTATCCTTATGAAGGAGCTGATGAGAGCTGCAAGTTTAAGAAATCGGAAGCTGTTGTGTACATCAACTCCTCTGTTTCAATATCCAGCGATGAAAGCAAAATGGCAGCATGGCTAGTTGCTAATGGGCCAATTTCTATTGGTATCAATGCTAATATGATGCAGTTTTACTTGGGAGGAATTGCTCATCCGTGGAAAATGTTCTGTGATCCCTCAGAGCTTGATCATGGTGTGCTAATTGTCGGTTATGGAGTCAAGAAAGGCTGGTTTGACGATACACCATACTGGATTATCAAGAACAgTTGGGGAGAAAGCTGGGGAGAAGAGGGATACTACTTGATCTACCGCGGTGATGGATGCTGTGGTTTGAACACCATGTGTACCTCGGCTGTTGTCGACTAAGATGCAAGCTGACCAACTGGCTTTATTAAGGTCGACGTCAATGTTCAATTTATACTCCATTTTTTTACatcaattttagctttttagaTTTAATGCTAGTGTTTTAAAATACTCTTATTTTCTGTAATACAAATACGAATAATTGTTACTCTACGTTgtcaaatttgaaagctgatACCCGGTTAGGAAGACCAAGTAGGTAACTACACTCCTTAACTAAAGATGACTTTTAAGAGTTCTTTCAAAGTTATTTCTAGAGAATGAAATTTGGCATTCTCTTTGACCCTATTGAGAGTGACGCTTATAGGttctactctgtctaacgctggACGATTTTTCTTGTCAGTGGAGGCCGCGTTAGGCCtgggggtgaatgggttaacaagaTCTTgttccactcaaaaactatgtacCCTTTAAAGTACACACAGCTgaaagaaaagtaataaattttAGAGTCCTTTGGCTGAAACGAGAATGTCTTATGTAAGAGCTATCGAATCCTTGAGTCATGtcgaaaaataattgttttcaacaagatCTTTAACTTCTAGTTCATAGCACAACTATATGGGCAAAATGTTGAAGCTATCGAATATGTCTAGTAATTAGTTTTTCGATTGTATTTCAGTCTGTTATCTTACtcttaactttaaatttaactaACTGCATTtagttatatacatgtatgagcGGGTGAGTTTGTCGCCGAAAAGATTTAATTACTTTTGCTGCTTTtagtattttacatttttttaataaacagGGAAATAAAAGGGTATTTTCCAATTA

Protein

UniProt (Swiss-Prot top hit)

UniProt accession	Description
Q26534	Cathepsin L OS=Schistosoma mansoni OX=6183 GN=CL1 PE=2 SV=1
Q9UBX1	Cathepsin F OS=Homo sapiens OX=9606 GN=CTSF PE=1 SV=1
Q9R013	Cathepsin F OS=Mus musculus OX=10090 GN=Ctsf PE=1 SV=1

Gene family

Family type	Membership / link
Orthogroup (gene family)	OG0008892 (this species only) · gene tree & orthology

Pfam domain

Pfam accession	Pfam name	Description	Type	Source
PF08246 all species →	Inhibitor_I29	Cathepsin propeptide inhibitor domain (I29)	Domain	Interproscan
PF00112 all species →	Peptidase_C1	Papain family cysteine protease	Domain	Interproscan
PF00031 all species →	Cystatin	Cystatin domain	Domain	Interproscan

InterPro

InterPro term	Type	Description	Source
IPR013201 all species →	Domain	Cathepsin propeptide inhibitor domain (I29)	Interproscan
IPR046350 all species →	Homologous_superfamily	Cystatin superfamily	Interproscan
IPR000668 all species →	Domain	Peptidase C1A, papain C-terminal	Interproscan
IPR013128 all species →	Family	Peptidase C1A	Interproscan
IPR000010 all species →	Domain	Cystatin domain	Interproscan
IPR039417 all species →	Domain	Papain-like cysteine endopeptidase	Interproscan
IPR025660 all species →	Active_site	Cysteine peptidase, histidine active site	Interproscan
IPR025661 all species →	Active_site	Cysteine peptidase, asparagine active site	Interproscan
IPR000169 all species →	Active_site	Cysteine peptidase, cysteine active site	Interproscan
IPR038765 all species →	Homologous_superfamily	Papain-like cysteine peptidase superfamily	Interproscan

PANTHER

PANTHER term	Description	Source
PTHR12411 all species →	CYSTEINE PROTEASE FAMILY C1-RELATED	Interproscan

Gene Ontology

GO term	Category	Description	Source
GO:0006508 all species →	Biological Process	proteolysis	Interproscan
GO:0008234 all species →	Molecular Function	cysteine-type peptidase activity	Interproscan
GO:0004197 all species →	Molecular Function	cysteine-type endopeptidase activity	Interproscan
GO:0005615 all species →	Cellular Component	extracellular space	Interproscan
GO:0005764 all species →	Cellular Component	lysosome	Interproscan
GO:0051603 all species →	Biological Process	proteolysis involved in protein catabolic process	Interproscan
GO:0004869 all species →	Molecular Function	cysteine-type endopeptidase inhibitor activity	Interproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.

KEGG pathway

KO	Enzyme	Enzyme ID	Pathway	Map ID	Source
K01373	CTSF; cathepsin F	EC:3.4.22.41	Peptidases and inhibitors	ko01002	deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068746743.1 across 36 RNA-seq samples of Montipora capricornis. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples

30TPM > 0

1Conditions

658.8Max TPM

292.3Mean TPM

By condition

Condition	Samples	TPM > 0	Mean TPM	Max TPM	Mean, relative to max
Polyps	36	30	292.31	658.76

Per sample · hover a bar for the full sample record · show / hide the sample table

SRA run	Condition	Tissue	Developmental stage	Treatment	Study	TPM
SRR12786897	Polyps	Polyps	OA3 day0	not recorded	SRP199550	658.76
SRR12786898	Polyps	Polyps	OA3 day0	not recorded	SRP199550	656.78
SRR12786896	Polyps	Polyps	OA3 day0	not recorded	SRP199550	655.18
SRR12959230	Polyps	Polyps	E3 day3	not recorded	SRP199550	431.48
SRR12710857	Polyps	Polyps	OA3 day9	not recorded	SRP199550	356.14
SRR12710855	Polyps	Polyps	OA3 day9	not recorded	SRP199550	355.60
SRR12959227	Polyps	Polyps	E3 day3	not recorded	SRP199550	353.62
SRR12710858	Polyps	Polyps	OA3 day9	not recorded	SRP199550	350.34
SRR12959184	Polyps	Polyps	E3 day0	not recorded	SRP199550	347.51
SRR12959183	Polyps	Polyps	E3 day0	not recorded	SRP199550	347.18
SRR12959182	Polyps	Polyps	E3 day0	not recorded	SRP199550	336.83
SRR12710848	Polyps	Polyps	OA3 day3	not recorded	SRP199550	325.21
SRR12710847	Polyps	Polyps	OA3 day3	not recorded	SRP199550	323.66
SRR27940191	Polyps	Polyps	not recorded	not recorded	SRP199550	319.40
SRR12904783	Polyps	Polyps	not recorded	not recorded	SRP199550	317.18
SRR12710846	Polyps	Polyps	OA3 day3	not recorded	SRP199550	316.83
SRR12959229	Polyps	Polyps	E3 day3	not recorded	SRP199550	314.16
SRR12959189	Polyps	Polyps	E3 day21	not recorded	SRP199550	309.07
SRR12959216	Polyps	Polyps	E3 day9	not recorded	SRP199550	306.65
SRR12959214	Polyps	Polyps	E3 day9	not recorded	SRP199550	301.79
SRR12959202	Polyps	Polyps	E3 day15	not recorded	SRP199550	300.17
SRR12959201	Polyps	Polyps	E3 day15	not recorded	SRP199550	299.48
SRR12959203	Polyps	Polyps	E3 day15	not recorded	SRP199550	298.46
SRR12959188	Polyps	Polyps	E3 day21	not recorded	SRP199550	297.83
SRR12959190	Polyps	Polyps	E3 day21	not recorded	SRP199550	296.46
SRR12959215	Polyps	Polyps	E3 day9	not recorded	SRP199550	291.03
SRR27940193	Polyps	Polyps	not recorded	not recorded	SRP199550	266.97
SRR12904781	Polyps	Polyps	not recorded	not recorded	SRP199550	265.22
SRR27940192	Polyps	Polyps	not recorded	not recorded	SRP199550	264.22
SRR12904782	Polyps	Polyps	not recorded	not recorded	SRP199550	260.03
SRR12807381	Polyps	Polyps	OA3 day0	not recorded	SRP199550	0.00
SRR12849113	Polyps	Polyps	OA3 day0	not recorded	SRP199550	0.00
SRR12927880	Polyps	Polyps	E3 day0	not recorded	SRP199550	0.00
SRR12963484	Polyps	Polyps	E3 day0	not recorded	SRP199550	0.00
SRR9129316	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00
SRR9613519	Polyps	Polyps	not recorded	not recorded	SRP199550	0.00

Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.