Detailed information of XP_068748083.1 in Montipora capricornis

Genomic Location: chr4:8908960...8954656
NR annotation: XP_029191416.2, focal adhesion kinase 1-like isoform X1 [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families


 Gene Structure
More details in JBrowse  Sequence
CDS
Transcript
Protein
 UniProt (Swiss-Prot top hit)
UniProt accessionDescription
Q91738Focal adhesion kinase 1 OS=Xenopus laevis OX=8355 GN=ptk2 PE=2 SV=2
Q00944Focal adhesion kinase 1 OS=Gallus gallus OX=9031 GN=PTK2 PE=1 SV=2
P34152Focal adhesion kinase 1 OS=Mus musculus OX=10090 GN=Ptk2 PE=1 SV=4
 Gene family
Family typeMembership / link
Orthogroup (gene family)OG0003173 (this species only) · gene tree & orthology

 Pfam domain
Pfam accessionPfam nameDescriptionTypeSource
PF07714
all species →
PK_Tyr_Ser-ThrProtein tyrosine and serine/threonine kinaseDomainInterproscan
PF03623
all species →
Focal_ATFocal adhesion targeting regionDomainInterproscan
PF21477
all species →
FERM_C_FAK1FAK1/PYK2, FERM domain C-lobeDomainInterproscan
PF00373
all species →
FERM_MFERM central domainDomainInterproscan
PF18038
all species →
FERM_N_2FERM N-terminal domainDomainInterproscan

 InterPro
InterPro termTypeDescriptionSource
IPR019748
all species →
DomainFERM central domainInterproscan
IPR011009
all species →
Homologous_superfamilyProtein kinase-like domain superfamilyInterproscan
IPR001245
all species →
DomainSerine-threonine/tyrosine-protein kinase, catalytic domainInterproscan
IPR005189
all species →
DomainFocal adhesion kinase, targeting (FAT) domainInterproscan
IPR011993
all species →
Homologous_superfamilyPH-like domain superfamilyInterproscan
IPR049385
all species →
DomainFAK1-like, FERM domain C-lobeInterproscan
IPR014352
all species →
Homologous_superfamilyFERM/acyl-CoA-binding protein superfamilyInterproscan
IPR008266
all species →
Active_siteTyrosine-protein kinase, active siteInterproscan
IPR041784
all species →
DomainFAK1/PYK2, FERM domain C-lobeInterproscan
IPR036137
all species →
Homologous_superfamilyFocal adhesion kinase, targeting (FAT) domain superfamilyInterproscan
IPR000299
all species →
DomainFERM domainInterproscan
IPR035963
all species →
Homologous_superfamilyFERM superfamily, second domainInterproscan
IPR017441
all species →
Binding_siteProtein kinase, ATP binding siteInterproscan
IPR019749
all species →
DomainBand 4.1 domainInterproscan
IPR020635
all species →
DomainTyrosine-protein kinase, catalytic domainInterproscan
IPR029071
all species →
Homologous_superfamilyUbiquitin-like domain superfamilyInterproscan
IPR000719
all species →
DomainProtein kinase domainInterproscan
IPR041390
all species →
DomainFocal adhesion kinase, N-terminalInterproscan

 PANTHER
PANTHER termDescriptionSource
PTHR46221
all species →
FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBERInterproscan

 Gene Ontology
GO termCategoryDescriptionSource
GO:0004672
all species →
Molecular Functionprotein kinase activityInterproscan
GO:0006468
all species →
Biological Processprotein phosphorylationInterproscan
GO:0004713
all species →
Molecular Functionprotein tyrosine kinase activityInterproscan
GO:0005925
all species →
Cellular Componentfocal adhesionInterproscan
GO:0007172
all species →
Biological Processsignal complex assemblyInterproscan
GO:0005856
all species →
Cellular ComponentcytoskeletonInterproscan
GO:0005524
all species →
Molecular FunctionATP bindingInterproscan

Search by domain instead of by gene. Any accession above (InterPro, Pfam, PANTHER, GO, KEGG) can be used as a query on the Functional Domain Search page, which searches all 148 annotated genomes at once.
 KEGG pathway
KOEnzymeEnzyme IDPathwayMap IDSource
K05725PTK2, FAK; focal adhesion kinase 1EC:2.7.10.2
Protein phosphatases and associated proteinsko01009deepkoala

Searching by KO or pathway ID across all species is available on the KEGG Pathway page.

Expression pattern (RNA-seq)

Transcript abundance of XP_068748083.1 across 36 RNA-seq samples of Montipora capricornis. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.

36Samples
0TPM > 0
1Conditions
0.0Max TPM
0.0Mean TPM

By condition

ConditionSamplesTPM > 0 Mean TPMMax TPMMean, relative to max
Polyps 36 0 0.00 0.00

Per sample · hover a bar for the full sample record

Show the sample table (36 samples)
SRA runConditionTissueDevelopmental stage TreatmentStudyTPM
SRR12710846 Polyps Polyps OA3 day3 not recorded SRP199550 0.00
SRR12710847 Polyps Polyps OA3 day3 not recorded SRP199550 0.00
SRR12710848 Polyps Polyps OA3 day3 not recorded SRP199550 0.00
SRR12710855 Polyps Polyps OA3 day9 not recorded SRP199550 0.00
SRR12710857 Polyps Polyps OA3 day9 not recorded SRP199550 0.00
SRR12710858 Polyps Polyps OA3 day9 not recorded SRP199550 0.00
SRR12786896 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12786897 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12786898 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12807381 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12849113 Polyps Polyps OA3 day0 not recorded SRP199550 0.00
SRR12904781 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR12904782 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR12904783 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR12927880 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12959182 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12959183 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12959184 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR12959188 Polyps Polyps E3 day21 not recorded SRP199550 0.00
SRR12959189 Polyps Polyps E3 day21 not recorded SRP199550 0.00
SRR12959190 Polyps Polyps E3 day21 not recorded SRP199550 0.00
SRR12959201 Polyps Polyps E3 day15 not recorded SRP199550 0.00
SRR12959202 Polyps Polyps E3 day15 not recorded SRP199550 0.00
SRR12959203 Polyps Polyps E3 day15 not recorded SRP199550 0.00
SRR12959214 Polyps Polyps E3 day9 not recorded SRP199550 0.00
SRR12959215 Polyps Polyps E3 day9 not recorded SRP199550 0.00
SRR12959216 Polyps Polyps E3 day9 not recorded SRP199550 0.00
SRR12959227 Polyps Polyps E3 day3 not recorded SRP199550 0.00
SRR12959229 Polyps Polyps E3 day3 not recorded SRP199550 0.00
SRR12959230 Polyps Polyps E3 day3 not recorded SRP199550 0.00
SRR12963484 Polyps Polyps E3 day0 not recorded SRP199550 0.00
SRR27940191 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR27940192 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR27940193 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9129316 Polyps Polyps not recorded not recorded SRP199550 0.00
SRR9613519 Polyps Polyps not recorded not recorded SRP199550 0.00

Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM, StringTie quantification over 36 runs), joined to SRA sample metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped by the descriptor carried in the expression matrix itself.

Co-expression network

Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.

DirectionPartnersMost correlated partnerPCC
Positively correlated0not in this network-
Negatively correlated0not in this network-

This gene has no edge at all in the Montipora capricornis network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.

Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.

Single-cell expression

Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.

No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.

Epigenetic marks

Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.

No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.

What you can do with this gene

Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.

AnalysisWhat it doesStatus
Primer designDesign PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed.template foundopen →
BLASTSearch this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start.template foundopen →
Expression heatmapDraw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it.no expression matrix
Gene family / orthogroupLook this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue.open →
Gene set analysisStart a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it.open →
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