Genomic Location: chr4:8908960...8954656
NR annotation: XP_029191416.2, focal adhesion kinase 1-like isoform X1 [Acropora millepora]
Species Montipora capricornis · all data for this species · gene families
| CDS |
| LOC138045468 |
| Transcript |
| rna-XM_068891982.1 |
| Protein |
| XP_068748083.1 |
| UniProt accession | Description |
|---|---|
| Q91738 | Focal adhesion kinase 1 OS=Xenopus laevis OX=8355 GN=ptk2 PE=2 SV=2 |
| Q00944 | Focal adhesion kinase 1 OS=Gallus gallus OX=9031 GN=PTK2 PE=1 SV=2 |
| P34152 | Focal adhesion kinase 1 OS=Mus musculus OX=10090 GN=Ptk2 PE=1 SV=4 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003173 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF07714 all species → | PK_Tyr_Ser-Thr | Protein tyrosine and serine/threonine kinase | Domain | Interproscan |
| PF03623 all species → | Focal_AT | Focal adhesion targeting region | Domain | Interproscan |
| PF21477 all species → | FERM_C_FAK1 | FAK1/PYK2, FERM domain C-lobe | Domain | Interproscan |
| PF00373 all species → | FERM_M | FERM central domain | Domain | Interproscan |
| PF18038 all species → | FERM_N_2 | FERM N-terminal domain | Domain | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR019748 all species → | Domain | FERM central domain | Interproscan |
| IPR011009 all species → | Homologous_superfamily | Protein kinase-like domain superfamily | Interproscan |
| IPR001245 all species → | Domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR005189 all species → | Domain | Focal adhesion kinase, targeting (FAT) domain | Interproscan |
| IPR011993 all species → | Homologous_superfamily | PH-like domain superfamily | Interproscan |
| IPR049385 all species → | Domain | FAK1-like, FERM domain C-lobe | Interproscan |
| IPR014352 all species → | Homologous_superfamily | FERM/acyl-CoA-binding protein superfamily | Interproscan |
| IPR008266 all species → | Active_site | Tyrosine-protein kinase, active site | Interproscan |
| IPR041784 all species → | Domain | FAK1/PYK2, FERM domain C-lobe | Interproscan |
| IPR036137 all species → | Homologous_superfamily | Focal adhesion kinase, targeting (FAT) domain superfamily | Interproscan |
| IPR000299 all species → | Domain | FERM domain | Interproscan |
| IPR035963 all species → | Homologous_superfamily | FERM superfamily, second domain | Interproscan |
| IPR017441 all species → | Binding_site | Protein kinase, ATP binding site | Interproscan |
| IPR019749 all species → | Domain | Band 4.1 domain | Interproscan |
| IPR020635 all species → | Domain | Tyrosine-protein kinase, catalytic domain | Interproscan |
| IPR029071 all species → | Homologous_superfamily | Ubiquitin-like domain superfamily | Interproscan |
| IPR000719 all species → | Domain | Protein kinase domain | Interproscan |
| IPR041390 all species → | Domain | Focal adhesion kinase, N-terminal | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46221 all species → | FERM AND PDZ DOMAIN-CONTAINING PROTEIN FAMILY MEMBER | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0004672 all species → | Molecular Function | protein kinase activity | Interproscan |
| GO:0006468 all species → | Biological Process | protein phosphorylation | Interproscan |
| GO:0004713 all species → | Molecular Function | protein tyrosine kinase activity | Interproscan |
| GO:0005925 all species → | Cellular Component | focal adhesion | Interproscan |
| GO:0007172 all species → | Biological Process | signal complex assembly | Interproscan |
| GO:0005856 all species → | Cellular Component | cytoskeleton | Interproscan |
| GO:0005524 all species → | Molecular Function | ATP binding | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K05725 | PTK2, FAK; focal adhesion kinase 1 | EC:2.7.10.2 | Protein phosphatases and associated proteins | ko01009 | deepkoala |
Transcript abundance of XP_068748083.1 across 36 RNA-seq samples of Montipora capricornis. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 36 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR12710846 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710847 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710848 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710855 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12710857 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12710858 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12786896 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12786897 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12786898 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12807381 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12849113 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12904781 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12904782 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12904783 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12927880 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959182 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959183 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959184 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959188 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959189 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959190 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959201 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959202 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959203 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959214 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959215 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959216 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959227 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959229 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959230 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12963484 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR27940191 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940192 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940193 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9129316 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613519 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM,
StringTie quantification over 36 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Montipora capricornis network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |