Genomic Location: chr5:10973313...11004979
NR annotation: CAH3177887.1, unnamed protein product [Porites evermanni]
Species Montipora capricornis · all data for this species · gene families
| CDS |
| LOC138049441 |
| Transcript |
| rna-XM_068895714.1 |
| Protein |
| XP_068751815.1 |
| UniProt accession | Description |
|---|---|
| E9Q5F9 | Histone-lysine N-methyltransferase SETD2 OS=Mus musculus OX=10090 GN=Setd2 PE=1 SV=1 |
| Q9BYW2 | Histone-lysine N-methyltransferase SETD2 OS=Homo sapiens OX=9606 GN=SETD2 PE=1 SV=3 |
| Q9VYD1 | Histone-lysine N-methyltransferase Set2 OS=Drosophila melanogaster OX=7227 GN=Set2 PE=1 SV=2 |
| Family type | Membership / link |
|---|---|
| Orthogroup (gene family) | OG0003818 (this species only) · gene tree & orthology |
| Pfam accession | Pfam name | Description | Type | Source |
|---|---|---|---|---|
| PF08236 all species → | SRI | SRI (Set2 Rpb1 interacting) domain | Domain | Interproscan |
| PF17907 all species → | AWS | AWS domain | Domain | Interproscan |
| PF00397 all species → | WW | WW domain | Domain | Interproscan |
| PF00856 all species → | SET | SET domain | Family | Interproscan |
| InterPro term | Type | Description | Source |
|---|---|---|---|
| IPR038190 all species → | Homologous_superfamily | Set2 Rpb1 interacting domain superfamily | Interproscan |
| IPR001202 all species → | Domain | WW domain | Interproscan |
| IPR001214 all species → | Domain | SET domain | Interproscan |
| IPR013257 all species → | Domain | Set2 Rpb1 interacting domain | Interproscan |
| IPR042294 all species → | Family | Histone-lysine N-methyltransferase SETD2, animal | Interproscan |
| IPR006560 all species → | Domain | AWS domain | Interproscan |
| IPR046341 all species → | Homologous_superfamily | SET domain superfamily | Interproscan |
| IPR044437 all species → | Domain | SETD2/Set2, SET domain | Interproscan |
| IPR003616 all species → | Domain | Post-SET domain | Interproscan |
| IPR036020 all species → | Homologous_superfamily | WW domain superfamily | Interproscan |
| PANTHER term | Description | Source |
|---|---|---|
| PTHR46711 all species → | HISTONE-LYSINE N-METHYLTRANSFERASE SETD2 | Interproscan |
| GO term | Category | Description | Source |
|---|---|---|---|
| GO:0005515 all species → | Molecular Function | protein binding | Interproscan |
| GO:0005694 all species → | Cellular Component | chromosome | Interproscan |
| GO:0006355 all species → | Biological Process | regulation of DNA-templated transcription | Interproscan |
| GO:0005634 all species → | Cellular Component | nucleus | Interproscan |
| GO:0010468 all species → | Biological Process | regulation of gene expression | Interproscan |
| GO:0016279 all species → | Molecular Function | protein-lysine N-methyltransferase activity | Interproscan |
| GO:0046975 all species → | Molecular Function | histone H3K36 methyltransferase activity | Interproscan |
| GO:0097198 all species → | Biological Process | obsolete histone H3-K36 trimethylation | Interproscan |
| GO:0042054 all species → | Molecular Function | histone methyltransferase activity | Interproscan |
| KO | Enzyme | Enzyme ID | Pathway | Map ID | Source |
|---|---|---|---|---|---|
| K11423 | SETD2; [histone H3]-lysine36 N-trimethyltransferase | EC:2.1.1.359 | Chromosome and associated proteins | ko03036 | deepkoala |
Transcript abundance of XP_068751815.1 across 36 RNA-seq samples of Montipora capricornis. This gene has no row in the species' RNA-seq expression matrix, so every value below is shown as zero — the matrix simply does not cover this transcript. Values are TPM (transcripts per million) from the StringTie quantification; one bar is one sample, grouped and coloured by condition, sorted by expression within each group.
| Condition | Samples | TPM > 0 | Mean TPM | Max TPM | Mean, relative to max |
|---|---|---|---|---|---|
| Polyps | 36 | 0 | 0.00 | 0.00 |
| SRA run | Condition | Tissue | Developmental stage | Treatment | Study | TPM |
|---|---|---|---|---|---|---|
| SRR12710846 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710847 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710848 | Polyps | Polyps | OA3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12710855 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12710857 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12710858 | Polyps | Polyps | OA3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12786896 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12786897 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12786898 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12807381 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12849113 | Polyps | Polyps | OA3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12904781 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12904782 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12904783 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR12927880 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959182 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959183 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959184 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR12959188 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959189 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959190 | Polyps | Polyps | E3 day21 | not recorded | SRP199550 | 0.00 |
| SRR12959201 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959202 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959203 | Polyps | Polyps | E3 day15 | not recorded | SRP199550 | 0.00 |
| SRR12959214 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959215 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959216 | Polyps | Polyps | E3 day9 | not recorded | SRP199550 | 0.00 |
| SRR12959227 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959229 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12959230 | Polyps | Polyps | E3 day3 | not recorded | SRP199550 | 0.00 |
| SRR12963484 | Polyps | Polyps | E3 day0 | not recorded | SRP199550 | 0.00 |
| SRR27940191 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940192 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR27940193 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9129316 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
| SRR9613519 | Polyps | Polyps | not recorded | not recorded | SRP199550 | 0.00 |
Source: CnidoSite RNA-seq expression matrices (MCAPR_TPM,
StringTie quantification over 36 runs), joined to SRA sample
metadata. Samples whose tissue/treatment is not recorded in the source metadata are grouped
by the descriptor carried in the expression matrix itself.
Genes whose expression across the transcriptome samples of Montipora capricornis tracks this one. Counts are over the whole network; the network view itself draws at most 100 partners per query gene (CNIDO_NET_TOP_K), so a hub gene can show fewer edges than the number below.
| Direction | Partners | Most correlated partner | PCC |
|---|---|---|---|
| Positively correlated | 0 | not in this network | - |
| Negatively correlated | 0 | not in this network | - |
This gene has no edge at all in the Montipora capricornis network, in either direction — it is not one of the genes the network was built from (the network covers genes with enough expression variation across the transcriptome samples). The counts above are a property of the network, not a failed lookup.
Open this gene in Network Analysis → The network opens with the gene already entered and both directions selected. There you can add up to 9 more genes, switch between the positive and negative network, and export the edge list.
Whether this gene can be visualised in the single-cell atlases of Montipora capricornis, and in which cell types it is a marker. Expression is stored per cell, so the violin plot and the cell-type means are computed in the viewer — open a dataset to see them.
No single-cell dataset has been published for this species. The atlases that do exist are listed in the Cell Atlas.
Chromatin and DNA-methylation data covering this gene. Peak calls are listed per sample with the genomic region the peak falls in; DNA methylation is listed as sample availability only, because those tables are queried by the DNA Methylation page itself.
No epigenomic data has been deposited for this species. The assays that exist across the site are described in the Epigenomic Data module.
Every tool below opens with this gene already entered, so you land on the analysis rather than on an empty form. Links open in a new tab.
| Analysis | What it does | Status | |
|---|---|---|---|
| Primer design | Design PCR / qPCR primers on this gene’s sequence with the published primer3 settings. Opens with the primers already computed. | template found | open → |
| BLAST | Search this gene’s sequence against the CnidoSite BLAST databases. The query is filled in and the species’ database is preselected — press Run to start. | template found | open → |
| Expression heatmap | Draw this gene’s expression as a heatmap across all RNA-seq samples, and compare it with the genes you add next to it. | no expression matrix | – |
| Gene family / orthogroup | Look this gene up in the single-copy orthogroups built from the high-quality cnidarian genomes, and see which other species carry an orthologue. | open → | |
| Gene set analysis | Start a gene-set enrichment analysis with this gene as the seed list. Add more genes on that page before running it. | open → |
